What Is Premenstrual Syndrome (PMS)?

Signs and Symptoms of Premenstrual Syndrome (PMS)
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- Depression
- Irritability and anger
- Crying
- Anxiety
- Trouble concentrating
- Loss of interest in sex
- Sleeping too much or too little
- Food cravings or appetite changes
Causes and Risk Factors of Premenstrual Syndrome (PMS)
How Is Premenstrual Syndrome (PMS) Diagnosed?
- Start within five days before a period and happen at least three months in a row
- Stop within four days after the period starts
- Affect at least some daily activities
Treatment and Medication Options for Premenstrual Syndrome (PMS)
Medication Options
PMS treatments include a combination of over-the-counter and prescription medicines that relieve both physical and emotional symptoms.
- Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin) and naproxen (Aleve) help with symptoms like headaches, cramps, and breast soreness. You can take an NSAID at the start of or right before your period to reduce these symptoms. Avoid using these medicines long-term, because they can cause side effects like stomach bleeding and ulcers (sores).
- Hormonal birth control methods like the pill stop ovulation, which may lessen PMS symptoms. You may need to try a few types of birth control to find one that helps.
- Antidepressants improve depression and other mood changes related to PMS, but they don't work for everyone. Selective serotonin reuptake inhibitors (SSRIs) like fluoxetine (Prozac), paroxetine (Paxil, Pexeva), and sertraline (Zoloft) are the antidepressants most often used for PMS. To prevent PMS-related mood changes, many women only use them in the two weeks before a period, whereas others take them daily.
- Diuretics, also called water pills, remove extra fluid from the body. They can help with symptoms like bloating and breast soreness. Diuretics should not be combined with NSAIDs, as they may cause kidney problems when taken together.
Complementary and Integrative Therapies
These vitamins and minerals have more evidence to support their use for PMS:
- Calcium may help with symptoms like tiredness, food cravings, and depression.The recommended dose is 1,200 milligrams (mg) a day, which can come from foods like dairy (milk, cheese, yogurt) and fortified products (juice, cereals), or from a supplement.
- Vitamin B6 might be helpful for mood changes, anxiety, irritability, and bloating. This vitamin is found in foods like fish, chicken, potatoes, and fortified cereals, or you can get it from a supplement. The recommended dose for PMS is 50 to 100 mg daily.
- Magnesium is thought to reduce bloating, breast soreness, mood symptoms, and menstrual migraines. This mineral is found in foods like leafy green vegetables (spinach), whole grains, nuts, and fortified cereals.
- Omega-3 fatty acids from fish, flaxseeds, and leafy green vegetables may be helpful for reducing cramps.
Some people find these complementary practices helpful for relieving PMS symptoms:
- Yoga Not only does this series of poses strengthen the body, it also improves PMS symptoms like bloating, sore breasts, and cramps.
- Meditation Focusing and calming the mind with meditation reduces stress, which may be helpful for PMS symptoms.
- Massage Therapy This treatment is used to reduce stress, release muscle tightness, and help you relax.
- Biofeedback In this treatment, you're connected to a device that helps you learn how to control body functions such as heart rate, breathing, and muscle activity. Biofeedback helps to promote a state of relaxation.
- Self-hypnosis With this technique, you put your mind into a deep state of relaxation and then use the power of suggestion to change behaviors and improve symptoms.
Lifestyle Changes for Premenstrual Syndrome (PMS)
Eat a Well-Balanced Diet
Stay Active
Practice Good Sleep Hygiene
- Keep your bedroom dark, quiet, comfortable, and cool.
- Try to go to bed and wake up at the same time each day.
- Exercise for 30 minutes early in the day, preferably outside where you're exposed to sunlight.
- Avoid known sleep disrupters like alcohol and caffeine before bedtime.
- Do something calming before bed, like taking a warm bath, reading a book, or meditating.
Stop Smoking
Premenstrual Syndrome (PMS) Prognosis
How Many People Have Premenstrual Syndrome (PMS)?
Related Conditions to Premenstrual Syndrome (PMS)
These mental health conditions often occur together with PMS:
- Major depressive disorder is persistent sadness and loss of interest in daily activities.
- Dysthymic disorder is a milder, long-term form of depression.
The Takeaway
- Premenstrual syndrome (PMS) is a group of physical and emotional symptoms that occur a week or two before a menstrual period.
- About 75 percent of women experience PMS at some point during their reproductive years.
- Treatments like NSAIDs, birth control pills, and antidepressants help to relieve PMS symptoms.
- Some women find that lifestyle changes like exercise, a well-balanced diet, and relaxation techniques improve their symptoms.
Common Questions & Answers
Resources We Trust
- Mayo Clinic: Premenstrual Syndrome (PMS)
- Office on Women's Health: Premenstrual Syndrome (PMS)
- The American College of Obstetricians and Gynecologists: Premenstrual Syndrome (PMS)
- Mind: Premenstrual Dysphoric Disorder (PMDD)
- International Association for Premenstrual Disorders (IAPD): Support
- Premenstrual Syndrome (PMS). Office on Women's Health. February 3, 2025.
- Premenstrual Syndrome. MedlinePlus. January 11, 2024.
- Premenstrual Syndrome (PMS). The American College of Obstetricians and Gynecologists. May 2021.
- Menstrual Cycle. Cleveland Clinic. December 9, 2022.
- Gudipally PR et al. Premenstrual Syndrome. StatPearls. July 17, 2023.
- Premenstrual Syndrome. Cleveland Clinic. January 20, 2025.
- Premenstrual Syndrome (PMS). Mayo Clinic. February 25, 2022.
- Premenstrual Syndrome: Learn More — Treatment for PMS. InformedHealth.org. May 18, 2022.
- Tsai S. Effect of Yoga Exercise on Premenstrual Symptoms among Female Employees in Taiwan. International Journal of Environmental Research and Public Health. July 16, 2016.
- Çetin NS et al. The Effect of a Mindfulness-Based Stress Reduction Program on Premenstrual Symptoms: A Randomized Controlled Trial. Journal of Midwifery & Women's Health. September-October 2023.
- What is Self-Hypnosis and How Do I Do It? Cleveland Clinic. February 17, 2023.
- Premenstrual Syndrome (PMS). Johns Hopkins Medicine.
- Premenstrual Syndrome — Self Care. MedlinePlus. June 1, 2025.
- American Heart Association Recommendations for Physical Activity in Adults and Kids. American Heart Association. January 19, 2024.
- Summer JV. Period Insomnia. Sleep Foundation. March 22, 2024.
- Choi SH et al. Association Between Smoking and Premenstrual Syndrome: A Meta-Analysis. Frontiers in Psychiatry. November 26, 2020.
- Premenstrual Syndrome. MedlinePlus. April 16, 2024.
- Alwafa RA et al. Prevalence of Premenstrual Syndrome and Its Association with Psychosocial and Lifestyle Variables: A Cross-Sectional Study from Palestine. BMC Women's Health. June 5, 2021.
- Menstrually Related Mood Disorders. UNC School of Medicine.
- Eccles H et al. The Association Between Premenstrual Dysphoric Disorder and Depression: A Systematic Review. Journal of Affective Disorders Reports. February 21, 2023.
- Sadr SS et al. Premenstrual Syndrome and Comorbid Depression Among Medical Students in the Internship Stage: A Descriptive Study. Iranian Journal of Psychiatry and Behavioral Sciences. Winter 2014.

Kara Smythe, MD
Medical Reviewer
Kara Smythe, MD, has been working in sexual and reproductive health for over 10 years. Dr. Smythe is a board-certified fellow of the American College of Obstetricians and Gynecologists, and her interests include improving maternal health, ensuring access to contraception, and promoting sexual health.
She graduated magna cum laude from Florida International University with a bachelor's degree in biology and earned her medical degree from St. George’s University in Grenada. She completed her residency in obstetrics and gynecology at the SUNY Downstate Medical Center in Brooklyn, New York. She worked in Maine for six years, where she had the privilege of caring for an underserved population.
Smythe is also passionate about the ways that public health policies shape individual health outcomes. She has a master’s degree in population health from University College London and recently completed a social science research methods master's degree at Cardiff University. She is currently working on her PhD in medical sociology. Her research examines people's experiences of accessing, using, and discontinuing long-acting reversible contraception.
When she’s not working, Smythe enjoys dancing, photography, and spending time with her family and her cat, Finnegan.
