Low Estrogen Symptoms

Signs and Symptoms of Low Estrogen
- Hot flashes or night sweats: A decline in estrogen confuses the part of your brain that controls body temperature. You might feel sudden warmth, redness, and sweating, especially on your face and neck. About 75 percent of perimenopausal women experience hot flashes.
- Dry skin: Your skin may appear dull and more wrinkled.
- Weak bones: With less estrogen, you may lose bone density, which can increase your risk of fractures.
- Change in mood: You may feel irritable, sad, anxious, or frustrated.
- Vaginal atrophy: The tissues of your vagina and urethra become dry and thin. This can lead to urinary tract infections (UTIs).
- Irregular periods or no periods: Your periods might come at different times or not at all.
- Trouble concentrating: You may feel like you have brain fog and frequently lose your train of thought.
- Weight gain: The added weight usually accumulates in your belly.
- Headaches: They often happen before or during your period.
- Painful sex: When estrogen levels are low, your vagina is less lubricated, which can result in discomfort during intercourse.
- Fatigue: You may feel extremely tired and lack energy when estrogen levels are low.
- Insomnia: It’s common to have trouble falling asleep and staying asleep if you have low estrogen.
- Changes in hair growth: Some women notice more facial hair or thinning hair on their head.
Symptoms of Low Estrogen in Males
Types of Estrogen
- Estrone (E1) This is the main hormone that you produce during menopause and after.
- Estradiol (E2) Your body makes mostly estradiol during your reproductive years. This is the most potent form of estrogen.
- Estriol (E3) This is the hormone that your body produces during pregnancy.
Menopause is typically confirmed with a blood test showing elevated follicle-stimulating hormone (FSH) and low estradiol in a woman who has stopped menstruating for at least several months.
Potential Complications of Low Estrogen
Some possible complications include:
- Heart disease or stroke: Estrogen protects your heart by keeping blood vessels relaxed and open. With less estrogen, cholesterol can start to build up on your artery walls. This increases the risk of heart disease and stroke.
- Osteoporosis: A loss of estrogen can lead to osteoporosis (a condition that weakens bones). People with osteoporosis are more likely to develop bone fractures.
- Mental health conditions: Mood disorders, like depression, are linked to lower levels of estrogen.
- UTIs: Low estrogen may affect your urinary health, making you more vulnerable to infections.
When to See a Doctor
- Have not had your period for a year and start bleeding again if you are menopausal.
- Are 16 or older and have not started your period.
- Have regularly missed one or more periods.
The Takeaway
- Low estrogen is a common problem for women during perimenopause and menopause.
- Symptoms of low estrogen include hot flashes, painful intercourse, weight gain, mood changes, and more.
- Your doctor can help you figure out if your estrogen levels are within the normal range.
Resources We Trust
- Cleveland Clinic: Low Estrogen
- Mayo Clinic: Menopause
- Office on Women’s Health: Menopause Symptoms and Relief
- National Institute on Aging: What Is Menopause?
- Johns Hopkins Medicine: Introduction to Menopause
- Estrogen’s Effect on the Female Body. Johns Hopkins Medicine.
- Low Estrogen Levels in Menopause. University of Rochester Medical Center.
- Low Estrogen. Cleveland Clinic. February 8, 2022.
- Introduction to Menopause. Johns Hopkins Medicine.
- Estrogen: What It Does and 5 Benefits. Cleveland Clinic. January 5, 2022.
- Rochira V et al. Estrogens, Male Reproduction and Beyond. Endotext. March 21, 2023.
- Vandenput L et al. Estrogens as regulators of bone health in men. Nature Reviews Endocrinology. June 16, 2009.
- Menopause and Cardiovascular Risk. American Heart Association. September 12, 2024.
- Albert KM et al. Estrogen, Stress, and Depression: Cognitive and Biological Interactions. Annual Review of Clinical Psychology. February 20, 2019.
- Menopause symptoms and relief. Office on Women’s Health. January 10, 2025.

Elise M. Brett, MD
Medical Reviewer
Dr. Brett practices general endocrinology and diabetes and has additional certification in neck ultrasound and fine-needle aspiration biopsy, which she performs regularly in the office. She is voluntary faculty and associate clinical professor at the Icahn School of Medicine at Mount Sinai. She is a former member of the board of directors of the American Association of Clinical Endocrinology. She has lectured nationally and published book chapters and peer reviewed articles on various topics, including thyroid cancer, neck ultrasound, parathyroid disease, obesity, diabetes, and nutrition support.

Julie Lynn Marks
Author
Julie Marks is a freelance writer with more than 20 years of experience covering health, lifestyle, and science topics. In addition to writing for Everyday Health, her work has been featured in WebMD, SELF, Healthline, A&E, Psych Central, Verywell Health, and more. Her goal is to compose helpful articles that readers can easily understand and use to improve their well-being. She is passionate about healthy living and delivering important medical information through her writing.
Prior to her freelance career, Marks was a supervising producer of medical programming for Ivanhoe Broadcast News. She is a Telly award winner and Freddie award finalist. When she’s not writing, she enjoys spending time with her husband and four children, traveling, and cheering on the UCF Knights.