Ulcerative Colitis Symptoms

Learn about the common symptoms of ulcerative colitis, as well as how to identify severe symptoms that require immediate medical attention.
How Do I Spot the Signs and Symptoms of Ulcerative Colitis?
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Symptoms of Ulcerative Colitis
- Diarrhea
- Rectal bleeding, or passing stools that contain blood
- Belly pain and cramps
- Feeling an urgent need to poop
- An ongoing urge to poop even when your bowels are empty — a sensation known as tenesmus
- Severe tiredness
- Fever
- Nausea and vomiting
- Unwanted or unexpected weight loss
- Mild: Under four episodes of rectal bleeding a day
- Moderate: Four or more daily rectal bleeding episodes
- Severe: More than four daily episodes of rectal bleeding, as well as systemic symptoms and low blood levels of a liver protein called albumin

Types of Ulcerative Colitis
- Ulcerative proctitis: This form of the disease tends to be the least severe, usually affecting the rectum (bottom of the colon). Feeling urgency when you need to poop and having problems passing stool, along with rectal bleeding, may be the only symptoms of ulcerative proctitis.
- Left-sided colitis and proctosigmoiditis: This affects the rectum and colon up to an area called the descending colon, sometimes reaching a bend in the colon near the spleen called the splenic flexure. Bloody diarrhea, belly pain and cramps, appetite loss, and tenesmus may suggest left-sided colitis. Proctosigmoiditis is a subtype of left-sided colitis that causes inflammation in the rectum and the area just above the rectum called the sigmoid colon. Symptoms of proctosigmoiditis are similar to those of left-sided colitis.
- Pancolitis or extensive colitis: This affects the entire colon, starting at the rectum and continuing past the splenic flexure. Pancolitis might cause severe episodes of bloody diarrhea, belly pain, and significant weight loss.
Potential Complications of Ulcerative Colitis
- Anemia: Anemia occurs when levels of red blood cells are low, causing fatigue, pale skin, and reduced exercise capacity. Most often, it develops due to low iron levels caused by blood loss in the gut, higher inflammation levels, and a reduced ability to absorb and use iron.
- Ankylosing spondylitis: Around 1.7 percent of people with ulcerative colitis develop ankylosing spondylitis. The main symptoms of ankylosing spondylitis are pain and stiffness in the lower back, hips, or both, which gets worse after rest. Pain can also spread to other parts of the spine and the rest of the body.
- Bone issues: Both ulcerative colitis and the corticosteroid medications used to manage inflammation may lead to low bone mass and osteoporosis.
- Eye problems: Around 10 percent of people with inflammatory bowel disease experience eye problems. This can result in conditions such as uveitis, dry eye disease, keratopathy, and episcleritis, all of which are treatable.
- Primary sclerosing cholangitis: This occurs when ulcerative colitis inflammation causes scarring of the tubes, or bile ducts, that carry digestive juices from your liver to your gut. Over time, the scarring narrows and hardens the bile ducts, causing severe liver damage or infections.
- Joint inflammation: Arthritis is the most common complication of inflammatory bowel disease outside of the digestive system. This can lead to swollen, stiff, and painful joints throughout the body. Peripheral arthritis, or inflammation of the elbows, wrists, knees, and ankles, is more common in people with ulcerative colitis than in the general population, with the level of joint inflammation generally being in line with the level of colon inflammation.
- Skin inflammation: Various skin disorders are the second most common complication of ulcerative colitis outside of the colon, including erythema nodosum and pyoderma gangrenosum. Red bumps or small blisters on the shins or ankles may develop in people who live with ulcerative colitis.
- Blood clots: Ulcerative colitis makes blood clotting in the veins, arteries, and capillaries more likely. Depending on the location of the blood clots, they can be fatal.
- Canker sores: People with ulcerative colitis can develop canker sores, or painful sores on the tongue or the inside of the mouth. These ulcers may be round, small, gray, white, or yellow with a red border.
- Growth and development problems in children: Weight loss and reduced appetite can lead to growth and development problems in young children. These may include short stature, slow growth, slower weight gain than normal, and late puberty.
Severe Complications of Ulcerative Colitis
Ulcerative colitis can lead to serious and sometimes fatal complications, including the following:
- Fulminant colitis: One of the most serious and potentially life-threatening ulcerative colitis complications is fulminant colitis (also known as acute severe ulcerative colitis), a rare complication that leads to more than 10 bloody stools per day, continuous rectal bleeding, and severe anemia. Symptoms of fulminant colitis rapidly get worse and can lead to life-threatening complications.
- Toxic megacolon: Toxic megacolon occurs when a section of the colon becomes dilated and paralyzed, often stemming from fulminant colitis. Common symptoms include pain, a swollen belly (bloating), fever, shock, diarrhea, and a rapid heart rate. Using certain medications, such as antidiarrheal medicines, opioids, or anticholinergic drugs, can worsen the condition. Toxic megacolon can be fatal, as it increases the risk of shock, dehydration, and infection throughout the body. In many cases, toxic megacolon requires surgery to remove all or part of the colon and rectum.
- Perforated colon: Toxic megacolon can lead to a perforated colon, or a hole in the wall of the colon, and spillage of its contents into the abdomen. This can cause severe belly pain and cramps, fever, bloating, nausea, and vomiting. A perforated colon is a medical emergency requiring urgent surgery.
- Peritonitis: This is an infection of the abdominal wall, known as the peritoneum, that can occur due to leaking bowel contents after a perforated colon. You may experience severe belly pain, fever, nausea and vomiting, an inability to pass stools or gas, breathing problems, low blood pressure, and shock. You might also feel soreness, swelling, or fluid in the abdomen.
Ulcerative Colitis and Colorectal Cancer
When to See a Doctor
Ulcerative colitis isn’t usually fatal, but symptoms can be severe and interfere with daily life. It is important to see a gastroenterologist for ongoing checkups and care, even if you are not experiencing any symptoms.
- Abdominal pain
- Bloody stools
- Continuous diarrhea that doesn’t get better even if you take over-the-counter medications or make dietary changes
- Diarrhea that wakes you up from sleep
- A fever with no other explanation that continues for two or more days
- Nausea or vomiting that lasts for more than one day
- Skin lesions that won’t heal
- Joint pain that interferes with daily activities
- A feeling of increased bowel urgency
- An inability to gain an appropriate amount of weight (in children)
- Dehydration
The Takeaway
- Ulcerative colitis causes diarrhea, bloody stools, tenesmus, and abdominal pain and discomfort. The severity of the disease is usually based on how many bloody stools a person passes daily.
- The condition can also cause inflammation outside of the digestive tract, affecting the joints, skin, and eyes, as well as contributing to potential liver conditions.
- Different types of ulcerative colitis cause various other symptoms, depending on how much of the colon is affected.
- Contact 911 or go to an emergency room if you experience abdominal pain, continuous bloody stools, dehydration symptoms, fever, and a rapid heartbeat.
Resources We Trust
- Mayo Clinic: Ulcerative Colitis: Symptoms and Causes
- Crohn’s & Colitis Foundation: Living With Ulcerative Colitis
- UCLA Health: Ulcerative Colitis vs. Crohn’s Disease
- Stanford Medicine Children’s Health: Ulcerative Colitis in Children
- Johns Hopkins: Ulcerative Colitis Treatment
- Ulcerative Colitis. Cleveland Clinic. November 5, 2023.
- Symptoms and Causes of Ulcerative Colitis. National Institute of Diabetes and Digestive and Kidney Diseases. September 2020.
- Ulcerative Colitis. Mayo Clinic. November 22, 2024.
- Definition and Facts of Ulcerative Colitis. National Institute of Diabetes and Digestive and Kidney Diseases. September 2020.
- Lynch WD et al. Ulcerative Colitis. StatPearls. June 5, 2023.
- Feuerstein J et al. AGA Clinical Practice Guidelines on the Management of Moderate to Severe Ulcerative Colitis. Gastroenterology. April 2020.
- Pediatric Ulcerative Colitis. Yale Medicine.
- Types of Ulcerative Colitis. Crohn’s & Colitis Foundation.
- Ulcerative Colitis. NewYork-Presbyterian.
- Ulcerative Colitis: Symptoms and Causes. Mayo Clinic. November 22, 2024.
- Kilicl Y et al. Prevalence of Extraintestinal Manifestations in Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis. Inflammatory Bowel Diseases. February 2024.
- Anemia. Crohn’s & Colitis Canada.
- Lin A et al. Development of Ankylosing Spondylitis in Patients With Ulcerative Colitis: A Systematic Meta-Analysis. PLOS One. August 1, 2023.
- Fact Sheet: Eye Complications. Crohn’s & Colitis Foundation.
- Primary Sclerosing Cholangitis. Mayo Clinic. June 21, 2023.
- Arthritis and Joint Pain. Crohn’s & Colitis Foundation.
- Skin Complications. Crohn’s & Colitis Foundation.
- Canker Sores. Cleveland Clinic. June 9, 2022.
- Pabla BS et al. Assessing Severity of Disease in Patients With Ulcerative Colitis. Gastroenterology Clinics of North America. September 23, 2020.
- Ulcerative Colitis. National Organization for Rare Disorders. November 5, 2012.
- Toxic Megacolon. Johns Hopkins.
- Gastrointestinal Perforation. Cleveland Clinic. July 11, 2022.
- Peritonitis. Johns Hopkins.
- The Risk of Colorectal Cancer in Crohn’s Disease and Ulcerative Colitis Patients. Crohn’s & Colitis Foundation.
- Ulcerative Colitis. Mount Sinai. November 22, 2024.

Yuying Luo, MD
Medical Reviewer
Yuying Luo, MD, is an assistant professor of medicine at Mount Sinai West and Morningside in New York City. She aims to deliver evidence-based, patient-centered, and holistic care for her patients.
Her clinical and research focus includes patients with disorders of gut-brain interaction such as irritable bowel syndrome and functional dyspepsia; patients with lower gastrointestinal motility (constipation) disorders and defecatory and anorectal disorders (such as dyssynergic defecation); and women’s gastrointestinal health.
She graduated from Harvard with a bachelor's degree in molecular and cellular biology and received her MD from the NYU Grossman School of Medicine. She completed her residency in internal medicine at the Icahn School of Medicine at Mount Sinai, where she was also chief resident. She completed her gastroenterology fellowship at Mount Sinai Hospital and was also chief fellow.

Adam Felman
Author
As a hearing aid user and hearing loss advocate, Adam greatly values content that illuminates invisible disabilities. (He's also a music producer and loves the opportunity to explore the junction at which hearing loss and music collide head-on.)
In his spare time, Adam enjoys running along Worthing seafront, hanging out with his rescue dog, Maggie, and performing loop artistry for disgruntled-looking rooms of 10 people or less.