What Causes Stroke in Women?

Strokes are caused by a disruption in the blood supply to the brain, either because of a blocked artery in the brain, or because of bleeding from a blood vessel in the brain.
But women have risk factors for stroke that men don’t, including the onset of menopause and, for some women, pregnancy complications and the use of oral contraceptives.
Women are also more likely than men to have autoimmune conditions, some of which raise the risk of stroke.
Here’s what to know about risk factors in women, how to reduce your chances of having a stroke, and the signs and symptoms of stroke that warrant immediate medical attention.
Types of Stroke
There are two types of strokes.
- Ischemic stroke: This type of stroke occurs when a blood clot or a fatty deposit blocks an artery leading to the brain, reducing or completely stopping the blood flow. It is the most common type of stroke; approximately 85 percent of all strokes are classified as ischemic.
- Hemorrhagic stroke: A hemorrhagic stroke occurs when a blood vessel in the brain bursts, leading to bleeding in or around the brain.
Stroke Causes and Specific Risk Factors in Women
Many stroke risk factors are common to both men and women, but certain risks are unique to or at least more common in women.
- Have been diagnosed with endometriosis
- Experienced menopause before age 45
- Experienced hypertension during their pregnancies
- Lost ovarian function before age 40
The association recommends that healthcare providers screen for these conditions as part of their evaluation of a woman’s risk for stroke.
Estrogen
In postmenopausal women, the normal drop in estrogen levels is associated with a rise in cardiovascular risk, including risk for stroke.
Pregnancy
Autoimmune Conditions
Autoimmune diseases disproportionately affect women, and some of those diseases can increase stroke risk, due to the fact that they cause inflammation, which in turn causes plaque buildup in the arteries, narrowing blood vessels and blocking blood flow. Some conditions may also increase the risk of blood clots.
Autoimmune conditions that can raise the risk of stroke include:
- Systemic lupus erythematosus (lupus)
- Rheumatoid arthritis
- Antiphospholipid syndrome
- Scleroderma
Migraine With Aura
Race
Race may raise stroke risk for some women.

Are Strokes More Common in Women Than Men?
Age at Stroke
“Strokes still occur more often in older folks,” says Jennifer Wong, MD, a cardiologist and the medical director of noninvasive cardiology at MemorialCare Heart and Vascular Institute at Orange Coast Medical Center in Fountain Valley, California, “but we are seeing strokes occur at younger ages more often than previous years.”
Post-Stroke Outcomes
“Unfortunately, research has shown us that women tend to have a higher mortality rate and worse post-stroke outcomes than men,” says Hera A. Kamdar, MBBS, an assistant professor in the department of neurology at Wexner Medical Center in Columbus, Ohio.
“Some reasons for this are that women may have atypical stroke symptoms, which can lead to delayed recognition and treatment; and women, particularly younger women, are more likely to be misdiagnosed given atypical clinical presentations,” Dr. Kamdar says.
Warning Signs of Stroke in Women
- Balance Do you feel wobbly or unsteady on your feet?
- Eyes Are you seeing double or experiencing blurry vision?
- Face Does one side of your face droop? Or is your smile lopsided?
- Arms Do your arms or legs feel weak or numb?
- Speech Are you having difficulty speaking or understanding those around you?
- Time Call 911 or emergency services if any of these symptoms occur.
These aren’t the only signs of stroke, however. Women in particular may experience some different signs and symptoms.
“Women tend to have more vague symptoms such as generalized weakness or confusion,” Dr. Wong says. “Women also have reported other unusual symptoms such as facial pain, hiccups, and nausea.”
- Sudden severe headache
- Confusion or disorientation
- General weakness (as opposed to only on one side)
- Nausea or vomiting
These less typical symptoms may often be attributed to other conditions, such as stress, viral illnesses, or exhaustion. But any sudden symptom or loss of function should raise concerns and prompt an individual to seek immediate medical help.
The Takeaway
- Women have many of the same risk factors for stroke as men but also have some additional risk factors.
- Pregnancy complications, autoimmune diseases, and migraine with aura can increase a woman's stroke risk.
- Women are more likely than men to have atypical signs and symptoms of stroke, and those may be overlooked in the ER.
- A stroke can be life-changing. Talk to your doctor about your personal risk factors and what you can do to lower your risk.
Resources We Trust
- Cleveland Clinic: Signs of a Stroke
- Mayo Clinic: Women and Stroke: What You Need to Know
- Stroke Journal: Women Ages 35 and Younger Are 44% More Likely to Have an Ischemic Stroke Than Male Peers
- Centers for Disease Control and Prevention: About Women and Stroke
- American Heart Association: Is It Fatigue — or a Stroke? Women Shouldn’t Ignore These Warning Signs
- Stroke: Causes and Risk Factors. National Heart, Lung, and Blood Institute.
- Brown RD. What Is a Stroke? A Mayo Clinic Expert Explains. Mayo Clinic. 2022.
- What Is Hemorrhagic Stroke? American Stroke Association.
- Bushnell C et al. 2024 Guideline for the Primary Prevention of Stroke: A Guideline From the American Heart Association/American Stroke Association. Stroke. October 21, 2024.
- How Estrogen Supports Heart Health. Cleveland Clinic. February 6, 2024.
- Abou-Ismail MY et al. Estrogen and Thrombosis: a Bench to Bedside Review. Thrombosis Research. August 1, 2021.
- Women and Risk of Stroke Infographic. American Heart Association.
- About Pregnancy and Stroke. Centers for Disease Control and Prevention.
- Øie LR et al. Migraine and risk of stroke. Journal of Neurology, Neurosurgery & Psychiatry. March 26, 2020.
- Migraine and Stroke Risk. American Migraine Foundation. November 1, 2024.
- Aparicio HJ et al. Abstract 101: Early Onset Hypertension Increases Risk of Midlife Stroke Among Black Women. American Heart Association. February 1, 2024.
- Rexrode KM et al. The Impact of Sex and Gender on Stroke. Circulation Research. February 17, 2022.
- Women ages 35 and younger are 44% more likely to have an ischemic stroke than male peers. American Heart Association. January 24, 2022.
- Carcel C et al. Sex differences in treatment and outcome after stroke: Pooled analysis including 19,000 participants. Neurology. December 10, 2019.
- Signs of a Stroke: Act Quickly with ‘BEFAST’. Cleveland Clinic. January 15, 2025.
- Is it fatigue — or a stroke? Women shouldn’t ignore these warning signs. American Heart Association. May 31, 2019.

David Weisman, MD
Medical Reviewer
David Weisman, MD, is the director of the Clinical Trial Center at Abington Neurological Associates in Pennsylvania, where he has conducted numerous clinical trials into mild cognitive impairment and Alzheimer’s disease to develop disease-modifying drugs.
Dr. Weisman has dedicated his research career toward advancing new therapies for Alzheimer’s disease, focusing on clinical trials for the prevention and treatment of Alzheimer’s disease, mild cognitive impairment, and other dementias, and he devotes his clinical practice to memory and cognitive problems.
He received a bachelor's degree in philosophy from Franklin and Marshall College, then an MD from Penn State College of Medicine. After an internship at St. Mary’s Hospital in San Francisco, he completed his neurology residency at Yale, where he served as chief resident. He then went to the University California in San Diego for fellowship training in Alzheimer’s disease and other dementias.
Weisman has published papers and studies in journals such as Neurology, JAMA Neurology, Stroke, and The New England Journal of Medicine, among others.

Alexandra Frost
Author
Alex Frost is a Cincinnati-based journalist who specializes in health, wellness, parenting, and lifestyle writing. Her work has been published by the Washington Post, The Atlantic, Healthline, Health, the Huffington Post, Glamour, and Popular Science, among others.
Alex is also the founder of an editorial marketing agency that offers brand strategy and content collaboration across platforms and projects, and she works as an educator and writing coach to journalists and freelancers at all stages of their careers.
She received a bachelor's degree in mass communications and journalism and a master's degree in teaching. In her free time, she enjoys spending time with her five kids in their various activities, and camping.