What Is Staph Infection? Symptoms, Causes, Diagnosis, Treatment, and Prevention

Staph infections are caused by a type of bacteria called staphylococcus. These germs can live on your skin, in your mouth, and in your nose.
Most of the time, staph doesn’t cause a problem. But if the bacteria spreads deeper into your body, you can develop a serious, or even life-threatening, infection.
Types of Staph Infections
Skin Infections Caused by Staph
Some examples of skin infections that can be caused by staph include:
Invasive Staph Infections
Invasive staph infections happen when bacteria enter the bloodstream. Some types are:
Drug-Resistant Infections: MRSA
Signs and Symptoms of Staph Infection
Your symptoms of a staph infection will depend on what type of infection you have.
- Rapid breathing
- Fever or chills
- Changes in mental state, like confusion or disorientation
- Severe joint pain and swelling
- Vomiting

Causes and Risk Factors of Staph Infection
Anyone can get a staph infection, but certain factors increase your odds.
- Diabetes
- Human immunodeficiency virus or acquired immunodeficiency syndrome
- Cancer
- Kidney failure
- A skin condition, such as eczema
- An open wound, burn, or sore
- A respiratory illness, such as cystic fibrosis or emphysema
- A weakened immune system
People who’ve had a recent surgery or have been hospitalized also have an increased risk of developing staph infection.
- Has a lower cleanliness score (based on observations of odor, clutter, and grime)
- Is rented and crowded
- Houses people who share bedrooms, towels, or hygiene items
- Contains MRSA contamination on surfaces
Hygiene habits that reduce the risk of staph transmission among household members include showering instead of taking baths, brushing teeth twice daily, and practicing frequent handwashing.
How Is Staph Infection Diagnosed?
When to See a Doctor About Staph
- Any suspicious area of red or painful skin
- A high fever or fever accompanying skin symptoms
- Pus-filled blisters
Treatment and Medication Options for Staph Infection
Invasive staph infections usually require hospitalization for IV antibiotic treatment to fight the infection and other supportive treatment to help you heal.
Medication Options
- Cefazolin
- Nafcillin
- Oxacillin
- Vancomycin
- Daptomycin (Cubicin)
- Doxycycline
- Sulfamethoxazole and trimethoprim (Bactrim)
- Clindamycin
- Linezolid (Zyvox)
Complementary and Integrative Therapies
Always talk to your doctor before trying any type of complementary or integrative therapy.
Prevention of Staph Infection
Staph bacteria are everywhere. You can’t avoid contact with them completely, but you can reduce your risk of developing an infection.
Stay clean. Keeping your hands and body clean is the most important way to prevent a staph infection. Wash your hands frequently for at least 20 seconds at a time, and shower daily. If you don’t have soap handy for hand-washing, use a hand sanitizer that contains at least 60 percent alcohol.
Clean any wounds. Clean cuts, scrapes, and other injuries thoroughly with soap and water to rinse out dirt and bacteria.
Cover wounds. Put a bandage on any skin wounds until they heal completely.
Avoid sharing personal items. Don’t share towels, sheets, athletic equipment, or clothing with another person who might have a staph infection.
Change tampons frequently. If you use tampons, change them at least every four to eight hours to avoid developing toxic shock syndrome. Keeping tampons in for extended periods creates an environment that can cause bacteria to grow. It’s also a good idea to use the lowest absorbency tampon necessary to manage your menstrual flow.
Wash clothing and linens in hot water. If you or someone in your household has a staph infection, wash your clothes, towels, and bedding in hot water, using bleach, if possible. Dry the laundry in the dryer, making sure it is completely dry before you remove it.
Be careful about the food you eat. Wash your hands before preparing food or eating finger foods. Make sure that the hot foods you eat stay hot until you serve them, and the cold foods stay cold. The temperature of hot foods should be above 140 degrees F, and the temperature of cold foods should be below 40 degrees F. Don’t consume foods that don’t look or taste normal, or that may not have been stored safely.
Use clean razors to shave. If you get a staph infection in an area you normally shave, avoid shaving until the infection clears. If you must shave, use a clean disposable razor. Don’t ever share razors with other people.
Wash yourself and your clothing after playing sports. Athletes should shower right after a game, competition, or practice. Also, wash your workout clothes and uniforms regularly, and keep your equipment clean.
How Long Does Staph Infection Last?
The healing time for a staph infection depends on your age, your overall health, the type of infection you have, and what treatment you use.
The outlook for staph infections depends on the type of infection and how much it has spread in your body. Any underlying medical conditions may also influence how quickly you heal and recover.
Complications of Staph Infection
One of the most serious complications of a staph infection is when the bacteria invade the bloodstream and lead to sepsis, which is an inflammatory response caused by infections.
Sepsis can turn into septic shock, a life-threatening condition that causes your blood pressure to drop dramatically and additionally causes organ damage.
- Chronic pain and fatigue
- Anxiety
- Memory loss
- Amputations
- Worsened cognitive function
Research and Statistics: Who Has Staph Infection?
Staph bacteria are one of the most common causes of skin infections in the United States.
Disparities and Inequalities in Staph Infections
Anyone can develop a staph infection, but some research suggests that Black Americans in particular may be more susceptible to staph infections than other people.
More studies are needed to determine why MRSA affects different races at different rates.
Related Conditions
- Other types of bacteria, including streptococci
- Fungi that cause yeast infections, athlete’s foot, and toenail infections
- Parasites that can cause head lice, body lice, or scabies
- Viruses that cause shingles, herpes, and warts
Common Questions & Answers
The Takeaway
- Staphylococcus, or staph, infections are caused by bacteria commonly found on the skin.
- While many are minor skin infections, staph infections can become serious if the bacteria enter deeper into your body.
- Get medical help if you experience symptoms like a suspicious area of red or painful skin, pus-filled blisters, high fever, or fever accompanying skin symptoms.
- To protect yourself, keep cuts and wounds clean and covered, and practice good hygiene, especially handwashing.
Resources We Trust
- Mayo Clinic: Staph Infections
- Cleveland Clinic: Staph Infection
- Centers for Disease Control and Prevention: Staphylococcus Aureus Basics
- Johns Hopkins Medicine: Staphylococcal Scalded Skin Syndrome
- MedlinePlus: Staphylococcal Infections
- Staphylococcal Infections. MedlinePlus. November 8, 2023.
- Bush LM. Staphylococcus aureus Infections. Merck Manual. September 2025.
- Staph Infections. Mayo Clinic. May 25, 2022.
- Folliculitis. Mayo Clinic. August 31, 2022.
- Hordeolum (Stye). Johns Hopkins Medicine.
- Boils and Carbuncles. Mayo Clinic. September 18, 2021.
- Cellulitis. Cleveland Clinic. April 18, 2022.
- Impetigo. Mayo Clinic. April 19, 2023.
- Staphylococcal Scalded Skin Syndrome. Johns Hopkins Medicine.
- Staph Infection. Cleveland Clinic. June 7, 2022.
- Pyomyositis. Cleveland Clinic. May 16, 2025.
- Methicillin-resistant Staphylococcus aureus (MRSA). American Academy of Family Physicians. August 17, 2022.
- MRSA Infection. Mayo Clinic. November 8, 2022.
- Preventing Methicillin-resistant Staphylococcus aureus (MRSA). Centers for Disease Control and Prevention. July 8, 2024.
- Mork R et al. Longitudinal, Strain-Specific Staphylococcus Aureus Introduction and Transmission Events in Households of Children With Community-Associated Meticillin-Resistant S aureus Skin and Soft Tissue Infection: A Prospective Cohort Study. The Lancet: Infectious Diseases. February 2020.
- Antibiotic Treatment of Staphylococcal Infections in Adults. Merck Manual.
- Hayes G et al. Manuka Honey and Methylglyoxal Increase the Sensitivity of Staphylococcus Aureus to Linezolid. Letters in Applied Microbiology. June 2018.
- Medication for Staphylococcal Infections. NYU Langone Health.
- van der Vaart T et al. All-Cause and Infection-Related Mortality in Staphylococcus aureus Bacteremia, a Multicenter Prospective Cohort Study. Open Forum Infectious Diseases. November 30, 2022.
- Sepsis. National Institute of General Medicine Sciences. July 2024.
- FAQs. Sepsis Alliance.
- Clinical Overview of Methicillin-resistant Staphylococcus aureus (MRSA) in Healthcare Settings. Centers for Disease Control and Prevention. April 12, 2024.
- Kourtis A et al. Vital Signs: Epidemiology and Recent Trends in Methicillin-Resistant and in Methicillin-Susceptible Staphylococcus aureus Bloodstream Infections — United States. CDC Morbidity and Mortality Weekly Report. March 8, 2019.
- Ruffin F et al. Black and White Patients With Staphylococcus aureus Bacteremia Have Similar Outcomes but Different Risk Factors. Clinical Infectious Diseases. November 14, 2022.
- Rha B et al. Vital Signs: Health Disparities in Hemodialysis-Associated Staphylococcus aureus Bloodstream Infections — United States, 2017–2020. CDC Morbidity and Mortality Weekly Report. February 10, 2023.
- Skin Infections. MedlinePlus. April 24, 2024.

Jane Yoon Scott, MD
Medical Reviewer
Jane Yoon Scott, MD, is an infectious disease physician and an assistant professor of medicine at Emory University in Atlanta. Dr. Scott enjoys connecting with her patients, empowering them to understand and take ownership of their health, and encouraging them to ask questions so that they can make informed and thoughtful decisions.
She graduated with the highest honors from the Georgia Institute of Technology, then received her MD from the Medical College of Georgia. She completed her internal medicine residency training and chief residency at Temple University Hospital, as well as a fellowship in infectious diseases at Emory University. She is board-certified in both internal medicine and infectious diseases.
When she is not seeing patients, Dr. Scott works with neighboring health departments to promote public health, especially to communities that have been historically underserved. She also teaches medical trainees and lectures medical students at the Emory University School of Medicine.
In her free time, Dr. Scott appreciates a good coffee shop, weekend hikes, playing guitar, strolling through cities, sampling restaurants, and traveling to new places.

Julie Lynn Marks
Author
Julie Marks is a freelance writer with more than 20 years of experience covering health, lifestyle, and science topics. In addition to writing for Everyday Health, her work has been featured in WebMD, SELF, Healthline, A&E, Psych Central, Verywell Health, and more. Her goal is to compose helpful articles that readers can easily understand and use to improve their well-being. She is passionate about healthy living and delivering important medical information through her writing.
Prior to her freelance career, Marks was a supervising producer of medical programming for Ivanhoe Broadcast News. She is a Telly award winner and Freddie award finalist. When she’s not writing, she enjoys spending time with her husband and four children, traveling, and cheering on the UCF Knights.