The 9 Best Tick Repellents of 2025, According to Doctors

9 Doctor-Recommended Tick Repellents to Keep You Protected in 2025

Preventing a tick bite is preferable to treating one. While not every tick bite carries disease, cases of tick-borne illnesses have more than doubled since 2000, according to the Centers for Disease Control and Prevention (CDC), including Lyme disease, babesiosis, and Rocky Mountain spotted fever, among others.

Kseniya Kobets, MD, director of cosmetic dermatology at Montefiore Einstein Advanced Care in New York, says that when it comes to choosing a tick repellent, it’s paramount to look for products containing ingredients approved by the Environmental Protection Agency (EPA) and the CDC. “EPA registration attests that repellents are tested for safety and effectiveness and their effect on the environment,” she says. “The CDC only recommends ingredients shown to decrease disease transmission, which is important for preventing tick-borne illnesses like Lyme. Unapproved products may be ineffective or cause irritation.”

We’ve kept our list short and sweet, focusing our recommendations on doctor-recommended and health editor–vetted products that contain CDC- and EPA-approved ingredients. Ahead, discover how to treat skin, clothes, and gear with a variety of tick repellents — including sprays, wipes, and travel-friendly bottles.

Our Top Picks for The Best Tick Repellents

When to Consult a Doctor

Most people can safely remove a tick at home using tick removal products. According to Hannah Kopelman, DO, a New York–based physician and the chief medical officer at DermOnDemand, if a tick is “attached in a hard-to-reach area like the scalp, eyelid, or ear canal — or if part of the tick breaks off during removal — I recommend seeing a doctor. We can help ensure complete removal and evaluate whether a preventative antibiotic is needed based on risk factors.”

Premium Insect Repellent with 20% Picaridin, Lotion, 4-Ounce

Best Spray With Picaridin

Sawyer Picaridin Insect Repellent

Pros

  • 20 percent picaridin provides effective protection
  • Nongreasy, nonsticky, and virtually scentless formula
  • Skin-friendly
  • Material safe

Cons

  • May need reapplication after swimming or heavy sweating

Key Specs

  • Active ingredient: 20 percent picaridin
  • Type: Nonaerosol spray
  • Use: Skin
  • Scent: None
A favorite among Everyday Health editors, myself included, Sawyer Picaridin Insect Repellent provides long-lasting and effective protection (up to 12 hours) without the downsides often associated with DEET, such as skin irritations and potential toxicity, according to the CDC.

I use this product on myself and my 6-year-old, and I trust it enough to apply it directly to her skin.
Picaridin is a synthetic compound modeled after a natural pepper plant extract, and at this concentration (20 percent), it offers excellent repellency against ticks. It works by repelling and deterring hosts, so ticks move away from prey because they find picardin sensorially unpleasant. In other words, it throws off the tick’s senses.

“Picaridin is very effective for ticks,” Dr. Kopelman says. “I tend to prefer it for families or those with sensitive skin. Patients often tell me it feels better on their skin, and I agree.”

This particular formula is nongreasy, nonsticky, and lacks a strong odor, making it highly appealing for direct skin application. Dr. Kobets confirms that the 20 percent is an effective concentration of picaridin to use, which this formula contains. As a bonus, it won’t damage plastics or synthetic fabrics, making it safe for use on clothing, gear, and skin.

Best With DEET

Off! Sportsmen Deep Woods Insect Repellent 3

$12.99 at Amazon

Pros

  • 30 percent DEET offers powerful and long-lasting tick repellency
  • DEET is a well-established and proven active ingredient
  • Formula is sweat-resistant

Cons

  • 30 percent DEET concentration can be more irritating to sensitive skin
  • May damage fabric

Key Specs:

  • Active ingredient: 30 percent DEET
  • Type: Aerosol spray
  • Use: Skin
  • Scent: Chemical and pungent
For a tick repellant with DEET, Everyday Health editors love Off! Sportsmen Deep Woods Insect Repellent 3, primarily due to its balanced 30 percent concentration and sweat-protection formula. This level is highly effective for robust, long-lasting protection against ticks (up to eight hours), making it ideal for more outdoor activities where tick exposure is high.

“At 20 to 30 percent strength, DEET is effective against ticks,” says Kobets. “Try to look for products that last at least six to eight hours.”

Although higher concentrations of DEET exist, 30 percent hits the sweet spot, providing significant repellency without the excessive skin irritation or strong odor that can sometimes accompany products with 50 percent or more DEET. The science behind what makes DEET so effective also has to do with messing with a tick’s senses. In this case, it’s their ability to suss out the heat source of prey and potential hosts.

    Speaking of heat, this formula is sweat-resistant, which means less applications if you’re outdoors hiking or being active in high temperatures. The aerosol spray bottle makes application on skin and clothes easy, but be careful if you wear synthetic fabrics, as DEET may stain or damage them.

    Best With DEET for Extra Protection

    Ben’s Tick & Insect Repellent

    $21.98 at Amazon

    Pros

    • 98.11 percent DEET is the highest available concentration
    • Highly effective against virtually all biting insects
    • Ideal for extreme conditions 

    Cons

    • Higher likelihood of skin irritation
    • Very likely to damage plastics, synthetic fabrics, leather, and painted surfaces

    Key Specs

    • Active ingredient: 98.11 percent DEET
    • Type: Nonaerosol spray
    • Use: Skin
    • Scent: Chemical and pungent

    If you’re planning an outside adventure in an area with a densely populated insect and tick population, you want to give yourself extra protection. Ben’s Tick & Insect Repellent formula contains the highest concentration of DEET on the market, 98.11 percent.

    At this concentration, a single application delivers the longest possible duration of repellency (up to 10 hours) against ticks and other biting insects. It’s specifically formulated for situations where insect pressure is severe, such as deep woods expeditions, areas with high tick populations, and regions where insect-borne diseases are prevalent.

    “I tend to steer patients toward DEET if they’re heading into wooded or grassy areas,” says Kopelman. It’s ideal for those prioritizing maximum protection and coverage longevity above all else.

    Do note that this product does have a pungent chemical smell, as expected, and feels greasy on your skin.

    Best DEET Alternative

    Coleman SkinSmart Insect Repellent

    $7.99 at Amazon
    $9.99Now 20% Off

    Pros

    • 20 percent IR3535 is recognized by the CDC as an effective tick repellent
    • Nongreasy, fast-drying, and unscented
    • Gentle on skin and won’t harm plastics or synthetic fabrics

    Cons

    • Protection duration may be slightly less than high-concentration DEET or picaridin products

    Key Specs

    • Active ingredient: 20 percent IR3535
    • Type: Aerosol spray
    • Use: Skin
    • Scent: None
    Like DEET or picaridin products, IR3535, the star ingredient in this repellent, also works to confuse a tick’s senses — in this case, by binding to its antennae so it has a hard time finding its way to a host.

    IR3535 is chemically engineered to look like a naturally occurring amino acid. Our research finds that Coleman SkinSmart Insect Repellent, which contains 20 percent IR3535, provides reliable, long-lasting protection (up to eight hours) against ticks in low-population areas, making it a strong alternative to DEET. We especially like it when gardening or doing other outdoor activities for short periods of time.

    The product’s key advantage lies in its user-friendly profile: It’s nongreasy, fast-drying, and doesn’t have a strong odor, making it appealing to those who prioritize how products feel on their skin. Furthermore, IR3535 is generally considered safer for sensitive skin and does not damage plastics or synthetic materials, adding to its versatility for family use and on gear. It’s recommended for low-risk outdoor areas and for short durations of time. We trust IR3535 as an ingredient because the CDC has given it its stamp of approval, and as Kopelman notes, “It can work in lower-risk environments. If someone is just gardening or spending time in the backyard, it may be enough.”

    Best Oil of Lemon Eucalyptus Spray

    Repel Plant-Based Lemon Eucalyptus Insect Repellent Spray

    $9.76 at Amazon
    $13.99Now 30% Off

    Pros

    • Appeals to those seeking herbal alternatives to synthetic repellents
    • Offers some tick protection
    • Lemon eucalyptus aroma is refreshing
    • Won’t damage gear or clothing

    Cons

    • Not recommended for children under 3 years old
    • May not be as effective against as broad a range of insects as synthetic repellents
    • More frequent reapplication is needed

    Key Specs

    • Active ingredient: 30 percent OLE/PMD
    • Type: Nonaerosol spray
    • Use: Skin
    • Scent: Eucalyptus
    Repel Plant-Based Lemon Eucalyptus Insect Repellent spray is a great option for those who want a botanical tick repellent. Like the other ingredients in the products on our list, oil of lemon eucalyptus (OLE/PMD) is well researched and shown to be effective against different species of ticks.

    You may want to reapply more frequently than repellents containing DEET or picaridin.
    At a 30 percent concentration, this plant-based compound is CDC-approved and EPA-registered as a repellent against mosquitoes and ticks, but it’s best for people older than 3 years old.

    For the best results, Kopelman suggests “layering it with protective clothing or using it for short exposures only.”

    If you’re looking for an herbal tick repellent for brief outdoor adventures, in places where tick populations are low, this lemon eucalyptus spray delivers protection with a refreshing scent, unlike any other repellent on our list.

    Best for Travel

    Ranger Ready Repellent

    $23.74 at Amazon
    $24.99Now 5% Off

    Pros

    • 20 percent picaridin is effective and safe for travel gear
    • Provides significant protection duration, reducing the need for frequent reapplications
    • Trigger pump dispenser makes it easy to dispense, difficult to spill 

    Cons

    • Can be greasy on the skin

    Key Specs

    • Active ingredient: 20 percent picaridin
    • Type: Nonaerosol spray
    • Use: Skin
    • Scent: None

    Ranger Ready Repellent combines an effective 20 percent picaridin concentration with travel-friendly features. It offers long-lasting protection (up to 12 hours), which is crucial for travelers who need reliable protection without constant reapplications. 

    Importantly, picaridin is nondamaging to clothing, plastics, and gear, making it ideal for packing alongside luggage and electronics. Its no-scent formula is also a significant benefit when in close quarters during travel. Plus, it’s available in compact and Transportation Security Administration–compliant sizes, further cementing its status as a top travel companion, and our Everyday Health editors note that the trigger pump dispenser makes it easy to use, without fear of it spilling.

    Best Wipes

    Repel Insect Repellent Mosquito & Tick Wipes

    $8.99 at Amazon

    Pros

    • Mess-free application (avoids overspray)
    • Ideal for applying to exposed skin without getting it on clothes (unless intended)
    • Long-lasting protection

    Cons

    • Lower concentration of picaridin per wipe

    Key Specs

    • Active ingredient: 12 percent picaridin
    • Type: Wipes
    • Use: Skin
    • Scent: None

    Repel Insect Repellent Mosquito & Tick Wipes offer convenient application and an effective 12 percent picaridin concentration per wipe. The wipe format allows for precise and controlled application, minimizing overspray and making it easy to apply to specific areas of the skin, especially for children (when applied by an adult). 

    The concentration per wipe ensures robust and reliable protection against ticks (up to 10 hours), making it effective for various outdoor activities. For quick, mess-free application on the go, especially when you want to avoid aerosols, these wipes are a standout solution.

    Best for Clothing

    Sawyer Premium Insect Repellent Clothing, Gear & Tents

    $9.88 at Amazon
    $15.49Now 36% Off

    Pros

    • Kills ticks on contact, doesn’t just repel them
    • Remains effective through six washes
    • Complements skin repellents

    Cons

    • Requires drying time
    • Can be flammable when wet

    Key Specs

    • Active ingredient: 0.5 percent permethrin
    • Type: Nonaerosol spray
    • Use: Clothing
    • Scent: None
    This product is a leader among anti-tick clothing treatments because of its proven 0.5 percent permethrin concentration and its unique role as an insecticide for fabric, not a as repellent for skin.

    Permethrin bonds to fabric fibers and kills ticks on contact, providing an extra layer of protection beyond skin-applied repellents. “Permethrin-treated clothing is one of the best lines of defense against ticks,” Kopelman says.

    This concentration is specifically formulated for clothing and gear, offering long-lasting effectiveness through multiple washes (up to six washes or approximately six weeks). Its ability to kill ticks before they can bite, combined with its safety for use on clothing (once the product has dried), makes it an invaluable tool for serious outdoor enthusiasts and those in high-risk insect areas.

    Best for Gear

    Repel Permethrin Clothing & Gear Insect Repellent

    $4.97 at Amazon
    $5.99Now 17% Off

    Pros

    • Creates a tick-free zone around treated tents, tarps, and backpacks
    • Won’t affect the aesthetics or durability of your gear
    • Adds a robust layer of defense for comprehensive protection

    Cons

    • Gear needs to be fully dry before use or packing
    • Needs reapplication after exposure to significant rain or extended use

    Key Specs

    • Active ingredient: 0.5 percent permethrin
    • Type: Aerosol spray
    • Use: Clothing
    • Scent: None
    Repel Permethrin Clothing & Gear Insect Repellent has an effective 0.5 percent permethrin concentration that is specifically designed to be applied to and bond with fabrics.

     Similar to Sawyer’s offering, this product functions as an insecticide, killing ticks and other insects that come into contact with treated items.
    Its winning edge for gear lies in its reliable performance on items like tents, sleeping bags, backpacks, and other outdoor equipment. This provides a crucial perimeter of protection around your campsite or outdoor setup, enhancing overall tick defense. The 0.5 percent concentration is the industry standard for consumer-level permethrin fabric treatments, ensuring efficacy without oversaturation.

    It’s effective for up to two weeks before needing reapplication, unless the gear is exposed to rain.

    Comparison Table

    Superlative
    Hours Effective
    Active Ingredient
    Type
    Use
    Best spray with picaridin
    12
    20 percent picaridin
    Nonaerosol spray
    Skin
    Best with DEET
    8
    30 percent DEET
    Aerosol spray
    Skin
    Best with DEET for extra protection
    10
    98.11 percent DEET
    Nonaerosol spray
    Skin
    Best DEET alternative
    8
    20 percent IR3535
    Aerosol spray
    Skin
    Best oil of lemon eucalyptus spray
    6
    30 percent OLE/PMD
    Nonaerosol spray
    Skin
    Best for travel
    12
    20 percent picaridin
    Nonaerosol spray
    Skin
    Best wipes
    10
    12 percent picaridin per wipe
    Wipes
    Skin
    Best for clothing
    6 weeks, or 6 washes
    0.5 percent permethrin
    Nonaerosol spray
    Clothing
    Best for gear
    2 weeks
    0.5 percent permethrin 
    Aerosol spray
    Gear

    How We Chose the Best Tick Repellents

    We went to expert doctors in medical dermatology to advise us on the best tick repellents for skin, clothing, and gear that contain only effective and safe ingredients with CDC and EPA approval. These medical experts included:

    • Kseniya Kobets, MD, director of cosmetic dermatology at Montefiore Einstein Advanced Care in New York.
    • Hannah Kopelman, DO, a New York–based physician and chief medical officer at DermOnDemand

    What to Look for in a Tick Repellent

    When buying a tick repellent, it’s imperative to look for active ingredients approved by the EPA and CDC. Our experts contend that when it comes to repelling ticks, the following EPA- and CDC-approved ingredients are the gold standard: DEET, picaridin, and permethrin (for clothing).

    “Effective tick repellents contain 20 to 30 percent DEET, or 20 percent picaridin, or use 0.5 percent permethrin for treating clothing,” notes Kobets. IR3535 and OLE/PMD, which are also EPA- and CDC-approved repellents, are effective for short periods in areas that have low tick populations.

    Finally, try to look for products that last at least six to eight hours, according to Kobets.

    Are Natural Repellents Effective for Ticks?

    Experts in treating vector-borne illnesses recommend that people primarily consider a repellent’s efficacy, and that they look for products that have been approved by the CDC and EPA first and foremost. Kopelman notes that these approvals were granted after years of rigorous testing and “exist to help us avoid allergic reactions, irritation, and — most important — vector-borne illnesses like Lyme disease. It’s not just about convenience; it’s about real public health protection.”

    Best Types of Tick Repellent Application

    • Pump sprays: These are user-friendly and versatile, great for full-body use. Because they’re easy to handle and control, they’re also useful for targeted application, like if you’re trying to apply repellent to a particular part of your body. They’re also great for applying to socks.
    • Wipes: Kobets likes these for families. So, with adult help, these are useful for moving targets, like kids.
    • Aerosols: These are useful in covering large areas, like full-body applications. They can also be used effectively on clothes, like gear.

    Tips for Repelling Ticks

    Be aware and savvy about your environment. “Ticks tend to hang out in tall grass or wooded areas and attach lower on the body,” explains Kopelman. In addition to using a tick repellent product, Kopelman advises “wearing long pants and socks when hiking or gardening — physical barriers matter just as much as chemical ones.”

    FAQ

    What is the best way to repel ticks on humans?
    According to our experts, the most effective ingredients against ticks are DEET or picaridin on skin, and permethrin on clothing.
    Ticks are turned off by citrus scents, according to our experts, who recommend lemon eucalyptus oil for a natural alternative to synthetic repellents. However, they underscore that this type of protection should only be used for short periods of time, in areas with low tick populations.
    In addition to using EPA- and CDC-approved tick repellents, our experts advise using a physical barrier, such as clothing that covers your skin completely. Tucking your pants into long socks is a good tip, as is wearing light-colored clothing, so that you can better see ticks on your clothes. 

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    Jill Di Donato

    Author

    Jill has over 15 years of experience writing about women's health, wellness, and beauty. She has deep knowledge of buzzy products and what makes them popular with consumers. She's tested hundreds of skin care products, tools, and medical aesthetics procedures throughout her career, and she has interviewed top dermatologists, plastic surgeons, and holistic physicians to stay on top of the latest in skin health and wellness.

    Jill is the former associate editorial operations director of the beauty group at Dotdash Meredith, where she worked on brands such as Shape and Byrdie, editing health, fitness, skin care, wellness, and body care commerce content.

    She's also a former sex and relationship writer, and has made national television appearances to discuss sexual wellness topics for women. In addition to anything beauty and sexual wellness, Jill specializes in writing about body neutrality and mental health.

    Jill has a degree in sociology, with a focus on gender studies and she has taught sociology classes at Barnard and Columbia University.

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    Simran Malhotra, MD

    Medical Reviewer
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    Dr. Malhotra completed her internal medicine residency at Medstar Franklin Square Medical Center, where she also served as chief resident in 2015. She completed her fellowship in hospice and palliative medicine at Johns Hopkins Hospital in 2016. She was named Top Doc in Palliative Medicine in 2019 and 2020 by Baltimore Magazine.

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