9 Doctor-Recommended Tick Repellents to Keep You Protected in 2025
We’ve kept our list short and sweet, focusing our recommendations on doctor-recommended and health editor–vetted products that contain CDC- and EPA-approved ingredients. Ahead, discover how to treat skin, clothes, and gear with a variety of tick repellents — including sprays, wipes, and travel-friendly bottles.
Our Top Picks for The Best Tick Repellents
- Best with picaridin: Sawyer Picaridin Insect Repellent
- Best with DEET: Off! Sportsmen Deep Woods Insect Repellent 3
- Best with DEET for extra protection: Ben’s Tick & Insect Repellent
- Best DEET alternative: Coleman SkinSmart Insect Repellent
- Best oil of lemon eucalyptus spray: Repel Plant-Based Lemon Eucalyptus Insect Repellent Spray
- Best for travel: Ranger Ready Repellent
- Best wipes: Repel Insect Repellent Mosquito & Tick Wipes
- Best for clothing: Sawyer Premium Insect Repellent Clothing, Gear & Tents
- Best for gear: Repel Permethrin Clothing & Gear Insect Repellent
When to Consult a Doctor
Most people can safely remove a tick at home using tick removal products. According to Hannah Kopelman, DO, a New York–based physician and the chief medical officer at DermOnDemand, if a tick is “attached in a hard-to-reach area like the scalp, eyelid, or ear canal — or if part of the tick breaks off during removal — I recommend seeing a doctor. We can help ensure complete removal and evaluate whether a preventative antibiotic is needed based on risk factors.”

Best Spray With Picaridin
Sawyer Picaridin Insect Repellent
Pros
- 20 percent picaridin provides effective protection
- Nongreasy, nonsticky, and virtually scentless formula
- Skin-friendly
- Material safe
Cons
- May need reapplication after swimming or heavy sweating
Key Specs
- Active ingredient: 20 percent picaridin
- Type: Nonaerosol spray
- Use: Skin
- Scent: None
This particular formula is nongreasy, nonsticky, and lacks a strong odor, making it highly appealing for direct skin application. Dr. Kobets confirms that the 20 percent is an effective concentration of picaridin to use, which this formula contains. As a bonus, it won’t damage plastics or synthetic fabrics, making it safe for use on clothing, gear, and skin.

Best With DEET
Off! Sportsmen Deep Woods Insect Repellent 3
Pros
- 30 percent DEET offers powerful and long-lasting tick repellency
- DEET is a well-established and proven active ingredient
- Formula is sweat-resistant
Cons
- 30 percent DEET concentration can be more irritating to sensitive skin
- May damage fabric
Key Specs:
- Active ingredient: 30 percent DEET
- Type: Aerosol spray
- Use: Skin
- Scent: Chemical and pungent
Speaking of heat, this formula is sweat-resistant, which means less applications if you’re outdoors hiking or being active in high temperatures. The aerosol spray bottle makes application on skin and clothes easy, but be careful if you wear synthetic fabrics, as DEET may stain or damage them.

Best With DEET for Extra Protection
Ben’s Tick & Insect Repellent
Pros
- 98.11 percent DEET is the highest available concentration
- Highly effective against virtually all biting insects
- Ideal for extreme conditions
Cons
- Higher likelihood of skin irritation
- Very likely to damage plastics, synthetic fabrics, leather, and painted surfaces
Key Specs
- Active ingredient: 98.11 percent DEET
- Type: Nonaerosol spray
- Use: Skin
- Scent: Chemical and pungent
If you’re planning an outside adventure in an area with a densely populated insect and tick population, you want to give yourself extra protection. Ben’s Tick & Insect Repellent formula contains the highest concentration of DEET on the market, 98.11 percent.
At this concentration, a single application delivers the longest possible duration of repellency (up to 10 hours) against ticks and other biting insects. It’s specifically formulated for situations where insect pressure is severe, such as deep woods expeditions, areas with high tick populations, and regions where insect-borne diseases are prevalent.

Best DEET Alternative
Coleman SkinSmart Insect Repellent
Pros
- 20 percent IR3535 is recognized by the CDC as an effective tick repellent
- Nongreasy, fast-drying, and unscented
- Gentle on skin and won’t harm plastics or synthetic fabrics
Cons
- Protection duration may be slightly less than high-concentration DEET or picaridin products
Key Specs
- Active ingredient: 20 percent IR3535
- Type: Aerosol spray
- Use: Skin
- Scent: None
IR3535 is chemically engineered to look like a naturally occurring amino acid. Our research finds that Coleman SkinSmart Insect Repellent, which contains 20 percent IR3535, provides reliable, long-lasting protection (up to eight hours) against ticks in low-population areas, making it a strong alternative to DEET. We especially like it when gardening or doing other outdoor activities for short periods of time.

Best Oil of Lemon Eucalyptus Spray
Repel Plant-Based Lemon Eucalyptus Insect Repellent Spray
Pros
- Appeals to those seeking herbal alternatives to synthetic repellents
- Offers some tick protection
- Lemon eucalyptus aroma is refreshing
- Won’t damage gear or clothing
Cons
- Not recommended for children under 3 years old
- May not be as effective against as broad a range of insects as synthetic repellents
- More frequent reapplication is needed
Key Specs
- Active ingredient: 30 percent OLE/PMD
- Type: Nonaerosol spray
- Use: Skin
- Scent: Eucalyptus
If you’re looking for an herbal tick repellent for brief outdoor adventures, in places where tick populations are low, this lemon eucalyptus spray delivers protection with a refreshing scent, unlike any other repellent on our list.

Best for Travel
Ranger Ready Repellent
Pros
- 20 percent picaridin is effective and safe for travel gear
- Provides significant protection duration, reducing the need for frequent reapplications
- Trigger pump dispenser makes it easy to dispense, difficult to spill
Cons
- Can be greasy on the skin
Key Specs
- Active ingredient: 20 percent picaridin
- Type: Nonaerosol spray
- Use: Skin
- Scent: None
Ranger Ready Repellent combines an effective 20 percent picaridin concentration with travel-friendly features. It offers long-lasting protection (up to 12 hours), which is crucial for travelers who need reliable protection without constant reapplications.
Importantly, picaridin is nondamaging to clothing, plastics, and gear, making it ideal for packing alongside luggage and electronics. Its no-scent formula is also a significant benefit when in close quarters during travel. Plus, it’s available in compact and Transportation Security Administration–compliant sizes, further cementing its status as a top travel companion, and our Everyday Health editors note that the trigger pump dispenser makes it easy to use, without fear of it spilling.

Best Wipes
Repel Insect Repellent Mosquito & Tick Wipes
Pros
- Mess-free application (avoids overspray)
- Ideal for applying to exposed skin without getting it on clothes (unless intended)
- Long-lasting protection
Cons
- Lower concentration of picaridin per wipe
Key Specs
- Active ingredient: 12 percent picaridin
- Type: Wipes
- Use: Skin
- Scent: None
Repel Insect Repellent Mosquito & Tick Wipes offer convenient application and an effective 12 percent picaridin concentration per wipe. The wipe format allows for precise and controlled application, minimizing overspray and making it easy to apply to specific areas of the skin, especially for children (when applied by an adult).
The concentration per wipe ensures robust and reliable protection against ticks (up to 10 hours), making it effective for various outdoor activities. For quick, mess-free application on the go, especially when you want to avoid aerosols, these wipes are a standout solution.

Best for Clothing
Sawyer Premium Insect Repellent Clothing, Gear & Tents
Pros
- Kills ticks on contact, doesn’t just repel them
- Remains effective through six washes
- Complements skin repellents
Cons
- Requires drying time
- Can be flammable when wet
Key Specs
- Active ingredient: 0.5 percent permethrin
- Type: Nonaerosol spray
- Use: Clothing
- Scent: None
Permethrin bonds to fabric fibers and kills ticks on contact, providing an extra layer of protection beyond skin-applied repellents. “Permethrin-treated clothing is one of the best lines of defense against ticks,” Kopelman says.
This concentration is specifically formulated for clothing and gear, offering long-lasting effectiveness through multiple washes (up to six washes or approximately six weeks). Its ability to kill ticks before they can bite, combined with its safety for use on clothing (once the product has dried), makes it an invaluable tool for serious outdoor enthusiasts and those in high-risk insect areas.

Best for Gear
Repel Permethrin Clothing & Gear Insect Repellent
Pros
- Creates a tick-free zone around treated tents, tarps, and backpacks
- Won’t affect the aesthetics or durability of your gear
- Adds a robust layer of defense for comprehensive protection
Cons
- Gear needs to be fully dry before use or packing
- Needs reapplication after exposure to significant rain or extended use
Key Specs
- Active ingredient: 0.5 percent permethrin
- Type: Aerosol spray
- Use: Clothing
- Scent: None
Comparison Table
How We Chose the Best Tick Repellents
We went to expert doctors in medical dermatology to advise us on the best tick repellents for skin, clothing, and gear that contain only effective and safe ingredients with CDC and EPA approval. These medical experts included:
- Kseniya Kobets, MD, director of cosmetic dermatology at Montefiore Einstein Advanced Care in New York.
- Hannah Kopelman, DO, a New York–based physician and chief medical officer at DermOnDemand
What to Look for in a Tick Repellent
“Effective tick repellents contain 20 to 30 percent DEET, or 20 percent picaridin, or use 0.5 percent permethrin for treating clothing,” notes Kobets. IR3535 and OLE/PMD, which are also EPA- and CDC-approved repellents, are effective for short periods in areas that have low tick populations.
Are Natural Repellents Effective for Ticks?
Best Types of Tick Repellent Application
- Pump sprays: These are user-friendly and versatile, great for full-body use. Because they’re easy to handle and control, they’re also useful for targeted application, like if you’re trying to apply repellent to a particular part of your body. They’re also great for applying to socks.
- Wipes: Kobets likes these for families. So, with adult help, these are useful for moving targets, like kids.
- Aerosols: These are useful in covering large areas, like full-body applications. They can also be used effectively on clothes, like gear.
Tips for Repelling Ticks
FAQ
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Jill Di Donato
Author
Jill has over 15 years of experience writing about women's health, wellness, and beauty. She has deep knowledge of buzzy products and what makes them popular with consumers. She's tested hundreds of skin care products, tools, and medical aesthetics procedures throughout her career, and she has interviewed top dermatologists, plastic surgeons, and holistic physicians to stay on top of the latest in skin health and wellness.
Jill is the former associate editorial operations director of the beauty group at Dotdash Meredith, where she worked on brands such as Shape and Byrdie, editing health, fitness, skin care, wellness, and body care commerce content.
She's also a former sex and relationship writer, and has made national television appearances to discuss sexual wellness topics for women. In addition to anything beauty and sexual wellness, Jill specializes in writing about body neutrality and mental health.
Jill has a degree in sociology, with a focus on gender studies and she has taught sociology classes at Barnard and Columbia University.

Simran Malhotra, MD
Medical Reviewer
Dr. Malhotra completed her internal medicine residency at Medstar Franklin Square Medical Center, where she also served as chief resident in 2015. She completed her fellowship in hospice and palliative medicine at Johns Hopkins Hospital in 2016. She was named Top Doc in Palliative Medicine in 2019 and 2020 by Baltimore Magazine.
On a personal note, she is a BRCA1 previvor with a strong family history of breast and female reproductive cancers, and underwent a risk-reducing bilateral mastectomy and total hysterectomy in 2020 at 32 years old. After learning about her own genetic risk of cancer, and grounded in her professional experiences in palliative care, she founded Wellness By LifestyleMD, a platform where she works with and educates women at high risk for cancer with or without genetic mutations on the powerful impact that positive lifestyle changes can have on their quality of life and even longevity.
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