10 Best Niacinamide Serums, Tested and Dermatologist-Approved

We Tested 10 Dermatologist-Recommended Niacinamide Serums — Here Are the Ones We Liked Best for Glowing Skin

When it comes to adding skin-care products to your routine, don’t miss out on niacinamide, a form of vitamin B3 that can help reduce the appearance of wrinkles, brighten skin, treat acne scars, shrink the appearance of pores, and improve hyperpigmentation.

“Niacinamide is an excellent ingredient for all skin types, especially mature, dry, and sensitive. It nourishes the barrier and calms redness and inflammation,” says Dendy Engelman, MD, a board-certified cosmetic dermatologist and Mohs surgeon specializing in youth-boosting treatments at the Shafer Clinic in New York City.

After consulting with two board-certified dermatologists, including Dr. Engelman and Michele Green, MD, a cosmetic dermatologist in New York City who specializes in youth-boosting and cosmetic treatments, we tested out over a dozen niacinamide serums to see which ones delivered on their promises. We tested the serums for six weeks, evaluating the efficacy of each one, as well as any additional beneficial ingredients. Then we narrowed down our list to the 10 most effective serums for various skin types and budgets.

Our Top Picks for the Best Niacinamide Serums

Best for Combination Skin

Tirtir Niacinamide 20 Percent Serum

$15.75 at Amazon
$25Now 37% Off

Pros

  • 20 percent niacinamide concentration delivers powerful results
  • Addresses both oiliness and dryness, common in combination skin
  • Contains skin-brightening ingredients
  • Lightweight and fast-absorbing

Cons

  • Sensitive skin types may take time to adjust to high niacinamide concentration

Key Specs

  • Consistency: Gel-like serum
  • Ingredients: 2 percent alpha arbutin, retinol
  • Skin type: All
This niacinamide serum from Tirtir is an exceptional choice for combination skin, due to its potent 20 percent concentration of niacinamide, which effectively targets the diverse needs of this skin type. “In order to see visible improvements in the skin, the concentration should be at least 4 percent,” says Dr. Green. “A niacinamide serum of 4 to 5 percent will work to improve skin texture, elasticity, and mild discoloration. For those who want an even stronger niacinamide, you can use a 10 percent or greater product.”

Combination skin often struggles with both oily T-zones and drier cheeks, and this serum’s high percentage of niacinamide works synergistically to regulate sebum production in oilier areas, minimizing shine and congestion, while simultaneously improving skin barrier function in drier zones, enhancing hydration, and reducing sensitivity.

Green adds that those with sensitive skin “should be careful to avoid irritation with higher percentages.” However, I could tolerate this on my combination skin without any irritation. The addition of 2 percent alpha arbutin and glutathione, a skin depigmenting agent, helped to lighten minor patches of discoloration in my skin due to sun spots.

This serum has been part of my routine for three months now, allowing me to track the changes in my skin.

Best for Dry Skin

The Outset Restorative Niacinamide Night Cream

$43.20 at Amazon
$54Now 20% Off

Pros

  • Strengthens and restores the skin barrier
  • Reduces dryness, flakiness, and tightness without irritation
  • Nongreasy despite its rich texture

Cons

  • Might be too rich for oily or acne-prone skin

Key Specs

  • Consistency: Cream
  • Ingredients: Hyaluroset, bakuchiol
  • Skin type: Dry, sensitive
The Outset Restorative Niacinamide Night Cream stands out as the best for dry skin, due to its deeply nourishing and barrier-supporting formula. It not only hydrates but also helps repair the skin barrier, protecting against environmental stressors and locking in moisture.

“Those with dry skin will appreciate the added hydration from using a niacinamide cream product,” explains Green. Dry skin often suffers from a compromised barrier, leading to moisture loss and increased sensitivity. This cream, which is rich in niacinamide and other emollients like Hyaluroset, the brand’s signature botanical collagen, and bakuchiol, a retinol alternative that’s less irritating than traditional retinol, works to fortify the skin barrier.

When I tested it, the cream delivered long-lasting moisture without feeling greasy. It made my dry skin feel comfortable, supple, and noticeably healthier. I used it when I experienced flakiness and tightness, and it instantly smoothed my complexion and strengthened my skin. It is on the pricier side, compared with other options on the list, but it is ideal for people following a vegan lifestyle, as it’s made with entirely botanical ingredients.

Best for Mature Skin

Saint Jane Star Flower Serum

$95 at Amazon

Pros

  • Addresses multiple signs of aging
  • Provides significant hydration and plumping
  • Brightens and evens out skin complexion
  • Formulated with beneficial botanical extracts

Cons

  • May not be suitable for those with sensitivities to essential oils, such as star fruit extract

Key Specs

  • Consistency: Fluid-like serum
  • Ingredients: Hyaluronic acid, star flower extract
  • Skin type: Dry, mature
Saint Jane Star Flower Serum is an exceptional choice for mature skin, as it’s expertly formulated to address dullness, loss of elasticity, uneven tone, and fine lines and wrinkles, thanks to its hyaluronic acid and star flower extract.

Individuals over 35 are categorized as having “mature” skin and could benefit from incorporating niacinamide into their routine. “Similar to retinol, niacinamide helps mitigate free radical damage and strengthen the skin barrier — without the irritating side effects most people experience with retinol,” says Engelman.

The serum’s lightweight, fluid texture makes it one of the most effective ways to deliver niacinamide to the skin, explains Green. “For many of my patients, a niacinamide serum will provide the most benefit, [especially] as a serum that is lightweight and easily absorbs,” she says. The star flower gives the serum a pearlized look that leaves skin looking dewy, perfect for my morning routine.

After six weeks of daily use, my skin felt more hydrated, and I needed less highlighter to achieve a radiant glow. This is an expensive product, but the pearlized finish lets it double as a makeup primer, making it worth the splurge.

Best for Pores

COSRX The Niacinamide 15 Serum

$17.99 at Amazon
$25Now 28% Off

Pros

  • Highly effective at minimizing the appearance of enlarged pores
  • Regulates sebum production, reducing oiliness
  • Gentle enough for daily use
  • Smoothes out skin texture

Cons

  • May not be hydrating enough for dry skin types
  • Small amount of product

Key Specs

  • Consistency: Gel-like serum
  • Ingredients: Zinc PCA
  • Skin type: Oily, acne-prone

COSRX The Niacinamide 15 Serum is ideal for addressing enlarged pores, due to its potent 15 percent concentration of niacinamide and its lightweight formula. “Individuals with oily skin will experience more benefits from a lighter formulation, such as a gel or pad, that does not clog their pores,” explains Green.

Because enlarged pores are often a result of excess sebum production and loss of skin elasticity, when you balance that oil production your pores may appear tighter and smaller.

This gel-like serum effectively regulates oil production, reducing the likelihood of pores becoming clogged and stretched. The formula also contains the anti-acne ingredient zinc PCA to control sebum production.

Simultaneously, niacinamide helps to improve skin elasticity, allowing the pore walls to appear tighter and less noticeable when less sebum is produced.

I found the lightweight texture absorbed into my skin quickly without any residue or uncomfortable tacky feeling. I have large pores on my cheeks, and after using this serum for six weeks, they looked less noticeable.

Best for a Dewy Complexion

Glow Recipe Watermelon Glow Niacinamide Dew Drops

$29.01 at Amazon
$36Now 19% Off

Pros

  • Instantly creates a radiant, dewy complexion
  • Brightens and evens out skin tone over time
  • Lightweight and nongreasy texture
  • Can be used alone or under makeup as a primer

Cons

  • The “dewy” effect might be too subtle for some
  • Some may find the watermelon scent strong

Key Specs

  • Consistency: Fluid-like serum
  • Ingredients: Hyaluronic acid, watermelon extract
  • Skin type: All
Glow Recipe Watermelon Glow Niacinamide Dew Drops lock in moisture and give the skin a dewy, luminous finish, thanks to the antioxidant-rich watermelon extract and hyaluronic acid.

The addition of these ingredients helps this niacinamide reduce the appearance of dullness, while locking in moisture and creating a plumping effect. “Niacinamide plays well with most other ingredients, working synergistically with nourishing ingredients like hyaluronic acid,” explains Engelman.
The formula is nongreasy and ideal for morning use, and its light-reflecting particles gave my skin a glassy look. It was so effective that I didn’t even need to apply highlighter to achieve a radiant glow. If you want to go bare skinned yet desire a dewy look, consider this serum in lieu of makeup. However, if you wish to layer on more products, such as a skin tint or highlighter for a more polished look, feel free to do so. Engelman notes that niacinamide is typically “very well-tolerated by most people, and generally interacts well with other skin-care ingredients.”

Best for Sensitive Skin

Paula’s Choice 10 Percent Niacinamide Booster

$46.55 at Amazon
$49Now 5% Off

Pros

  • Fragrance-free, dye-free, and nonirritating formula
  • Effectively reduces redness and inflammation
  • Improves skin barrier function and overall skin health

Cons

  • Can be a bit pricey for a booster product

Key Specs

  • Consistency: Gel-like serum
  • Ingredients: Hyaluronic acid, vitamin C
  • Skin type: Sensitive, acne-prone

This booster from Paula’s Choice is our top choice for sensitive skin, thanks to its meticulously formulated, fragrance-free approach to delivering the benefits of niacinamide. Sensitive skin requires gentle yet effective ingredients, and this booster excels by providing a potent 10 percent niacinamide concentration without fragrance, dyes, or alcohol.

Hyaluronic acid and vitamin C round out the formula and help reduce redness, improve uneven skin tone, and strengthen the skin barrier. “Vitamin C and hyaluronic acid work exceptionally well with niacinamide,” explains Green. “Vitamin C is an antioxidant that shields the skin from environmental damage by neutralizing free radicals generated by UV radiation. It combats oxidative stress and helps minimize signs of premature aging.” According to Green, vitamin C also promotes skin regeneration and collagen production, helps fade hyperpigmentation, and supports cellular repair.

I especially loved the lightweight liquid texture of this product and how quickly it absorbs into the skin. It is fairly expensive for a serum that’s marketed as a booster product, but if you have sensitive skin and want to avoid a reaction, a gentle serum like this may be worth the splurge.

Best Drugstore Buy

Olay Super Serum

$28.25 at Amazon
$34.99Now 19% Off

Pros

  • Excellent value because of the ingredient trio
  • Hydrating and suitable for daily use
  • Visibly improves skin texture, brightness, and firmness over time

Cons

  • Fragrance could be an issue for very sensitive skin

Key Specs

  • Consistency: Gel-like serum
  • Ingredients: Hyaluronic acid, Vitamin C
  • Skin type: All
Olay Super Serum is our drugstore standout because it offers a powerful trifecta of highly effective ingredients at an incredibly accessible price point. The formula includes niacinamide to help to repair barrier strength, plus vitamin C for brightening and antioxidant protection, and collagen peptides to support skin firmness and reduce the appearance of fine lines.

This comprehensive blend targets multiple skin concerns, making it a versatile and efficient everyday solution.

One potential drawback is that the product has a floral fragrance that smells more synthetic than botanical. This was not my preference, but others may feel differently. Ultimately, the value of this product is undeniable.

“Incorporating niacinamide into your skin-care routine can enhance skin clarity and luminosity, giving you a healthy, glowing appearance,” explains Green. When a drugstore product can do this effectively, it’s worth adding to your routine, especially if you’re on a budget.

Best Brightening

Drunk Elephant B-Goldi Bright Drops

$37.05 at Amazon
$39Now 5% Off

Pros

  • Delivers an instant radiant glow
  • Effectively brightens and evens out skin tone over time
  • Reduces the appearance of hyperpigmentation
  • Formula is free of harsh chemicals

Cons

  • Mica might not appeal to everyone for daily use

Key Specs

  • Consistency: Fluid-like serum
  • Ingredients: Diglucosyl gallic acid, squalane, mica
  • Skin type: Dull, all

Drunk Elephant B-Goldi Bright Drops contain a 5 percent concentration of niacinamide, which is the concentration Engelman recommends for best results. The formula also contains diglucosyl gallic acid, a powerful brightening ingredient that targets hyperpigmentation and is known for its skin-brightening properties. The “goldi” effect comes from light-reflecting particles that impart an instant, healthy glow, while key active ingredients help to improve skin clarity and brightness over time.

I liked applying this product daily in the morning, finding that the light-reflecting particles created a luminous effect, so much so that I could skip highlighter. The formula also contains squalane, a plant derivative, to provide light hydration without any greasy texture.

You may want to note that the shimmery effect is created by a mineral called mica, which might concern some. Mica has been associated with respiratory issues when inhaled daily.

This shouldn’t be an issue with skin-care products, as it is generally only a risk when mica particles are airborne. Despite these potent ingredients, I experienced no reactions while using it daily for six weeks. Engelman notes that “results are usually visible in about four to eight weeks, and improve with continued use.”
Elizabeth Arden retinol ceramide

Best for Eyes

Elizabeth Arden Retinol Ceramide Line Erasing Eye Cream

Pros

  • Effectively reduces the appearance of fine lines and wrinkles around the eyes
  • Strengthens the delicate skin barrier with ceramides
  • Hydrates and nourishes the eye area
  • Encapsulated retinol minimizes irritation often associated with retinoids

Cons

  • Higher price point
  • As with any retinol product, gradual introduction is advised, especially for those with sensitive eyes 

Key Specs

  • Consistency: Fluid-like serum
  • Ingredients: Ceramides, encapsulated retinol
  • Skin type: All

Elizabeth Arden Retinol Ceramide Line Erasing Eye Cream is Engelman’s pick for the delicate eye area. “Made with niacinamide, peptides, ceramides, and retinol, this clinically backed eye cream effectively de-puffs, smooths, and brightens under the eyes — improving the appearance of this area both immediately and over time,” she says.

This cream addresses aging skin around the eyes with encapsulated retinol, which gently yet effectively promotes cell turnover to diminish the appearance of lines and crow’s feet, all while being stabilized to minimize irritation.

Ceramides, crucial lipids for skin barrier function, work to replenish and fortify the fragile skin, preventing moisture loss and protecting against environmental damage.

At $79, this product is expensive, but the supporting ingredients make this dermatologist-backed formula worth the spend.
Medik8 peptide serum

Best for Acne-Prone Skin

Medik8 Clarity Peptides

Pros

  • Helps clear breakouts
  • Smooths out skin texture
  • Lightweight and easily absorbed
  • Suitable for blemish-prone and sensitive skin
  • Fights signs of aging

Cons

  • Users with sensitive skin may need to introduce product gradually and see slower results

Key Specs

  • Consistency: Cream
  • Ingredients: Peptides, zinc PCA
  • Skin type: Acne-prone
Medik8 Clarity Peptides combine peptides and niacinamide, offering a results-driven approach to achieving a clear, calm, and acne-free complexion, according to Engelman. “Formulated with 10 percent niacinamide, peptides, and hyaluronic acid, this powerful serum works to clarify the skin and even out skin tone while providing deep hydration,” she says. “It’s free of fragrances, synthetic colors, parabens, and alcohol.”

The peptide blend and zinc PCA address various skin concerns, from reducing breakouts to improving overall skin texture and tone.

Peptides, which are building blocks for collagen and elastin, help to strengthen and firm the skin while also contributing to a smoother appearance. The integration of niacinamide further amplifies its efficacy by reducing inflammation, minimizing pores, and balancing oil production, making it particularly effective for helping blemish-prone or uneven skin. This synergy between peptides and niacinamide delivers comprehensive improvements, resulting in visibly clearer, more refined, and healthier-looking skin with enhanced resilience.

Comparison Table

Superlative
Type of Niacinamide Serum
Skin Type
Ingredients
Best for combination skin
Gel-like serum
All
2 percent alpha arbutin, retinol
Best for dry skin
Cream
Dry, sensitive
Hyaluroset, bakuchiol
Best for mature skin
Fluid-like serum
Dry, mature
Hyaluronic acid, star flower extract
Best for pores
Gel-like serum
Oily, acne-prone
Zinc PCA
Best for a dewy complexion
Fluid-like serum
All
Hyaluronic acid, watermelon extract
Best for sensitive skin
Gel-like serum
Sensitive, acne-prone
Hyaluronic acid, Vitamin C
Best drugstore buy
Gel-like serum
All
Hyaluronic acid, vitamin C
Best brightening
Fluid-like serum
Dull, all
Diglucosyl gallic acid, squalene, mica
Best for eyes
Cream
All
Ceramides, encapsulated retinol
Best for acne-prone skin
Cream
Acne-prone
Peptides, zinc PCA

How We Tested the Best Niacinamide Serums

I tested all of the niacinamide serums on this list at home daily for four to six weeks. While some of the products were new to me, others have been a part of my routine skin-care regimen for years.

When testing niacinamide serums, I evaluated how well the serum brightened my complexion, removed minor hyperpigmentation spots, reduced the appearance of pore size, and diminished the look of fine lines and wrinkles. I also considered how well the product absorbed into my skin and whether it left a tacky or sticky feeling.

Finally, I consulted with the following medical doctors for their expertise:

  • Dendy Engelman, MD, a dermatologist and Mohs surgeon in New York City
  • Michele Green, MD, a dermatologist in New York City

What to Look for When Buying a Niacinamide Serum

Your skin type is the best way to determine what type of product you should choose. Because niacinamide can be found in serums, moisturizers, and cleansers, Green makes the following recommendations:

  • Those with oily or acne-prone skin should use niacinamide fluid-like serums, which absorb more quickly than moisturizers.
  • Those with dry or mature skin types should use a moisturizer with niacinamide, which will hydrate skin and improve the skin barrier.
  • Those with normal or combination skin types should use gel-like serums.

What to Avoid in a Niacinamide Serum

Depending on your skin type, you may want to avoid formulas that pair niacinamide with certain active ingredients. For example, if you have sensitive skin, choosing a niacinamide serum with retinol may cause irritation.

You also want to pay attention to the concentration of niacinamide. “The ideal concentration of niacinamide depends on your skin type and the results you are looking to achieve,” says Engelman. “The minimum recommended concentration is about 2 percent (those with sensitive skin may find this lower concentration more comfortable), but I would recommend 4 to 5 percent for best results.”

What Is Niacinamide, and What Does It Do for Your Skin?

“Niacinamide, a powerful form of vitamin B3, is highly regarded for its versatility in addressing various skin concerns,” says Green. “Its unique ability to regulate melanin production makes it a popular ingredient for reducing the appearance of dark spots and hyperpigmentation.”

Green further explains that niacinamide can help boost hydration, plump the skin, and minimize the appearance of fine lines and wrinkles.

What Skin-Care Ingredients Pair Well With Niacinamide?

According to Engelman, niacinamide works well in skin-care products such as serums and moisturizers, as well as active treatments like retinol and hydroxy acids. “It works synergistically with nourishing ingredients like hyaluronic acid and ceramides, and helps to offset irritation from harsher ingredients (like retinol and hydroxy acids).”

Green adds that hyaluronic acid and vitamin C are two of her favorite ingredients to pair with niacinamide. There are no ingredients to avoid when using a niacinamide serum. However, if you’re pairing niacinamide with a retinol, or if your niacinamide formula contains retinol, it’s important also use sunscreen.

FAQ

How often do I need to use niacinamide for it to be effective?
Both Green and Engelman recommend using niacinamide every day. However, they note that if you experience any irritation or sensitivity, you should let your dermatologist know. Engleman adds that niacinamide is typically “well-tolerated,” so the risk of irritation is low.
“Results are usually visible in about four to eight weeks,” explains Engelman, “and improve with continued use.”
Yes. Niacinamide is safe for “sensitive skin and irritated skin, due to its calming and nourishing properties,” explains Engelman.

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Jill Di Donato

Author

Jill has over 15 years of experience writing about women's health, wellness, and beauty. She has deep knowledge of buzzy products and what makes them popular with consumers. She's tested hundreds of skin care products, tools, and medical aesthetics procedures throughout her career, and she has interviewed top dermatologists, plastic surgeons, and holistic physicians to stay on top of the latest in skin health and wellness.

Jill is the former associate editorial operations director of the beauty group at Dotdash Meredith, where she worked on brands such as Shape and Byrdie, editing health, fitness, skin care, wellness, and body care commerce content.

She's also a former sex and relationship writer, and has made national television appearances to discuss sexual wellness topics for women. In addition to anything beauty and sexual wellness, Jill specializes in writing about body neutrality and mental health.

Jill has a degree in sociology, with a focus on gender studies and she has taught sociology classes at Barnard and Columbia University.

Orlando de Guzman

Fact-Checker

Orlando de Guzman is a writer and editor with expertise in health and environmental news. He has a background in investigative and science journalism and has worked on documentary films about war and trauma, health, sanitation, and the changing climate around the world. His interest in health and medicine started after an early career as a medical and legal translator.

De Guzman is a longtime health and fitness enthusiast who is interested in nutrition, diet, and mental health. He participates in endurance sports and cross-trains in several traditions of martial arts from Southeast Asia. De Guzman is interested in how the progressively complex movements of martial arts training can improve cognition and mental well-being, especially for those with PTSD and for those approaching middle age and beyond.

De Guzman has a dual B.A. in communications and international studies from the University of Washington in Seattle. He is committed to factual storytelling and evidence-based reporting on critical choices that affect our planet.

Alexandra Klausner

Editor

Alexandra Klausner is a freelance health writer and editor with over 10 years of journalism experience. Prior to going freelance, she worked as a reporter and editor at the New York Post for eight years covering everything from health and wellness to features and breaking news. Before that, she covered multiple beats at the Daily Mail Online for three years.

Alexandra graduated from Skidmore College in Saratoga Springs with a bachelor's degree in theater. As a New York City native, she is also a grant-winning playwright, actor, freestyle singer, catchy-hook writer, and podcaster. She loves yoga, 5 Rhythms dance meditation, and running.

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