The 9 Best Mosquito Repellents of 2025, According to Doctors

The 9 Best Doctor-Recommended Mosquito Repellents to Keep You Protected in 2025

Mosquito bites are itchy, pesky, and in some instances, can lead to vector-borne illnesses that pose real health risks. According to the Centers for Disease Control (CDC), the United States should continue to take mosquito-borne diseases seriously, and experts urge people to take proper precautions.

 Mosquito-borne illnesses like Zika, West Nile virus, and Dengue virus still pose ongoing concerns as recently as March 2025.

That’s not to say we should stay indoors when the weather is nice; quite the contrary. Besides the many physical and mental health benefits associated with outdoor activity, several mosquito repellents on the market are effective if you use them properly, allowing you to get the benefits of outdoor time without having to worry about bug bites.

We consulted with Dr. Kseniya Kobets, director of cosmetic dermatology at Montefiore Einstein Advanced Care in New York, and Dr. Hannah Kopelman, Chief Medical Officer at DermOnDemand, who practices in both New York City and Palm Beach County, Florida, about their favorite insect repellents. Our doctor-approved list comprises repellents that adhere to these standards—plus, we’ve added our favorite device, a spatial repellent for your porch or patio.

When to Consult a Doctor

If a mosquito bites you and you suspect the bite has become infected, see a doctor right away. Dr. Kopelman says you can tell a bug bite is infected if “it becomes increasingly red, warm, tender, swollen, or starts draining pus.” 

Additionally, if you experience swollen lymph nodes or a sudden fever, you should seek medical attention, according to Dr. Kopelman. “I always tell patients to watch for swelling that spreads beyond the bite site, difficulty breathing, hives, or dizziness—these could be signs of a systemic allergic reaction or even anaphylaxis, which is a medical emergency. Even localized allergic reactions that cause severe swelling (like lips or around the eyes) warrant medical attention.”

Best with DEET

OFF! Deep Woods Insect Repellent

$6.63 at Amazon
$6.98Now 5% Off

Pros

  • Provides reliable, long-lasting protection, up to eight hours
  • The aerosol format allows for broad, even application
  • The majority of users find it non-greasy
  • Widely available and a trusted name in insect repellents

Cons

  • Contains DEET, which some individuals prefer to avoid due to concerns about skin contact or a distinct chemical odor

Key Specs

  • Time effective: 8 hours
  • Active Ingredient: 25 percent DEET
  • Type: Aerosol spray
  • Use: Skin
  • Scent: Chemical and pungent

This aerosol spray has been a long-standing favorite for robust insect protection in outdoor settings, and it is our top pick for a mosquito repellent containing DEET. Its formulation is designed to deter a wide array of biting insects, including mosquitoes, ticks, and biting flies.


Off! Deep Woods Insect Repellent contains 25 percent DEET, which creates a vapor barrier around the skin that mosquitoes avoid. “In my experience, DEET is still the gold standard when it comes to repelling mosquitoes,” explains Dr. Kopelman. “I usually tell my patients to look for a formulation with around 20 to 30 percent DEET,” she says. This amount is adequate without the potential risk of skin irritation.

 Our research has found that this product is highly effective for extended periods in environments with significant insect activity. We should note our research found the scent of this product is a common point of discussion. While some find it tolerable, others note that the synthetic odor can be unpleasant.

Best with DEET for Extra Protection

Sawyer Products SP714 Premium Maxi DEET Insect Repellent

$9.89 at Amazon
$10.99Now 10% Off

Pros

  • Delivers exceptional protection for up to 10 hours in severe insect conditions
  • A little goes a long way
  • Can be applied to certain clothing items and gear, like mosquito nets 

Cons

  • Must apply sparingly due to high potency

Key Specs

  • Time effective: 10 hours
  • Active Ingredient: 98 percent DEET
  • Type: Pump spray
  • Use: Skin
  • Scent: Refined chemical
The 98 percent concentration of DEET in this formula exceeds Dr. Kopelman’s recommendations; however, certain situations require extra protection. Suppose you plan to go to an area with extremely dense bug populations. In that case, this high concentration of DEET ensures a more potent and longer-lasting effect in disrupting the mosquito's olfactory system.

For outdoor adventures that demand maximum protection against mosquitoes, this spray provides prolonged defense for up to 10 hours. In addition to its lasting power, we also like that it’s packaged as a non-aerosol pump spray, so you can control the application and avoid overapplying. Our research also found that the scent is well-tolerated because it lists a low-odor formulation.

Best with Picaridin

Sawyer Products SP543 Premium Insect Repellent with 20% Picaridin

$16 at Amazon
$20.89Now 23% Off

Pros

  • Effective for up to 12 hours against mosquitoes
  • Described as having little to no odor
  • Not sticky or greasy
  • Safe for use on clothing, backpacks, and other synthetic materials, as it won't damage plastics
  • Considered suitable for the entire family, including children as young as six months

Cons

  • Packaging can be leaky
  • May not be ideal for areas with heavy insect infestations

Key Specs

  • Time Effective: 12 hours
  • Active Ingredient: 20% Picaridin
  • Type: Pump spray
  • Use: Skin
  • Scent: None
This picaridin-based repellent is a popular alternative to DEET, offering effective protection that is often described as more comfortable on the skin and lasts up to 12 hours.

It has a pleasant mist feeling, unlike some of the greasier sprays on our list. According to our research, it doesn’t leave a lingering film, which also adds to the appeal of this spray. It’s ideal for those seeking a chemical-free mosquito repellent without the downsides usually associated with DEET, such as skin irritations and potential toxicity, according to the CDC.

It comes in a variety of sizes from 2 fluid ounces to 32 fluid ounces, making it perfect for traveling or keeping at home.
If you’re wondering about its effectiveness, picaridin works by creating a barrier that deters mosquitoes from landing on treated skin. Like DEET, it interferes with the mosquito's ability to locate a host by confusing its sensory organs.

 “Personally, I love recommending picaridin—especially for people who dislike the smell or feel of DEET. It’s odorless, non-greasy, and just as effective in many cases,” says Dr. Kopelman. “I’ve used it myself during travel and it works very well against mosquitoes.”

Best Oil of Lemon Eucalyptus Spray

Cutter Lemon Eucalyptus Insect Repellent

$5.89 at Walmart
$11.69Now 50% Off

Pros

  • Effective protection against mosquitoes for up to six hours
  • Refreshing lemon eucalyptus scent
  • Chemical-free formulation

Cons

  • Some note a slightly oily or sticky residue on the skin
  • Reapplication may be needed more frequently than with some chemical-based products

Key Specs

  • Time Effective: 6 hours
  • Active Ingredient: 30 percent OLE/PMD
  • Type: Pump spray
  • Use: Skin
  • Scent: Refined chemical
For those seeking a DEET-free repellent derived from a botanical source, look no further than Cutter Lemon Eucalyptus Insect Repellent. One of the key features of this 4 fluid ounce pump spray, is its scent, which our research notes has a “citronella like aroma.” This spray utilizes a 30 percent concentration of oil of lemon eucalyptus (OLE/PMD). It’s not just a pleasant scent that makes this a great pick for outdoor adventures; it has proven efficacy in deterring mosquitoes and other flying insects.


“I actually really like this option for people who want a botanical alternative,” says Dr. Kopelman. “I’ve had patients who swear by it—and the data supports that it can be quite effective. It’s a great pick if you’re looking for something plant-based but still potent.” Dr. Kobets is also a fan of this product, adding, “OLE/PMD has a strong mosquito protection.” It works by masking human odors that attract mosquitoes and repelling them with the PMD (Para-Menthane-3,8-diol) scent.

Mosquito repellant spray

Best for Kids

Zevo On Body Mosquito Repellent

Pros

  • Gentle on the skin and suitable for family use, including children
  • Odorless and non-sticky
  • Effective at repelling mosquitoes for up to six hours

Cons

  • Less potent compared to DEET or Picaridin
  • You may need to reapply more frequently for adequate protection

Key Specs

  • Time effective: 8 hours
  • Active Ingredient: 20 percent IR3535
  • Type: Aerosol spray
  • Use: Skin
  • Scent: None
Our pick of the best mosquito repellent for kids is the Zevo On Body Mosquito Repellent because it contains 20 percent IR3535, an active synthetic ingredient, similar to a naturally occurring amino acid, which is gentle on skin and effective against bugs.

The CDC deems it safe for both children and pregnant mothers, making it an ideal product for kids.

 

Our research has found that once applied, this product is odorless and non-sticky, which may help reduce complaints for kids (especially if they’re sensory-sensitive).
Similar to DEET and picaridin, IR3535 creates a protective barrier of scent molecules that confuses or overwhelms the mosquito's olfactory receptors, making the wearer less detectable as a blood meal source.

Although it’s listed as effective for up to eight hours, consider using this repellent for short outdoor exposures or in areas with a low mosquito population. Dr. Kobets tells us that, while it’s an effective repellent, it’s not as effective as formulas with DEET and picaridin.

Best Wipes

Ben's Tick & Insect Repellent Wipes

Pros

  • Convenient and portable, ideal for travel or on the go
  • Allows for precise application, especially for the face and neck
  • Water-based formula evaporates more slowly, ensuring protection up to seven hours

Cons

  • Direct hand contact with DEET is unavoidable during application
  • May not be ideal for full body coverage

Key Specs

  • Time effective: 7 hours
  • Active Ingredient: 30 percent DEET
  • Type: Wipes
  • Use: Skin
  • Scent: Chemical
The 30 percent DEET formulation provides reliable and durable protection up to seven hours against a variety of disease-carrying insects, including mosquitoes, ticks, flies, chiggers, and fleas.  The formula is alcohol-free and water-based, which means it will evaporate less quickly than alcohol-based formulas.

We love the convenience of these wipes, especially for people who don’t like the feel of an aerosol or pump spray on their skin, but it’s worth noting that they may not be adequate for full body coverage for adults, and aside from wearing gloves, there’s no way to prevent DEET from getting on your hands during application.

Best for Clothing

Sawyer Products Permethrin Fabric Treatment

$9.88 at Amazon
$15.49Now 36% Off

Pros

  • Highly effective against mosquitoes when applied to clothing
  • Lasts up to six weeks or six washes
  • Does not damage synthetic fabrics or other gear
  • Allows for skin to remain free of topical repellents

Cons

  • Must be applied to clothing and allowed to dry completely before wearing; not for direct skin application
  • Effectiveness may diminish over time with repeated washes or prolonged sun exposure if not re-treated

Key Specs

  • Time effective: 6 weeks or 6 washes
  • Active Ingredient: 0.5 percent permethrin
  • Type: Pump spray
  • Use: Clothes
  • Scent: None
Sawyer Products’ Permethrin Fabric Treatment is specifically designed for application to clothing and gear, providing an extra layer of protection against mosquitoes.

 It has a 0.5 percent concentration, which Dr. Kobets says is effective for clothing. You should note that if you want full body protection, you’ll also need to apply a repellent made for skin.

This product works by creating a barrier that repels and can even kill insects upon contact. When mosquitoes come into contact with clothing or gear treated with permethrin, it affects their nervous system, leading to disorientation, paralysis, and ultimately death.

 Once the application to clothing has dried, which typically takes a few hours but could take longer if you’re in a humid environment, the treatment is effective for up to six weeks or six washes, making it convenient for camping trips when you’re spending extended time outdoors.

Best for Gear

Repel Permethrin Clothing & Gear Insect Repellent

$4.97 at Amazon
$5.99Now 17% Off

Pros

  • Excellent for repelling and killing mosquitoes
  • Effective for multiple washes or for an extended time on untreated gear
  • Odorless once dry
  • Won't stain or damage fabrics

Cons

  • Spray nozzle may clog
  • Requires pre-planning, as items need to be treated and dried before use

Key Specs

  • Time effective: 2 weeks
  • Active Ingredient: 0.5 percent permethrin
  • Type: Pump spray
  • Use: Gear
  • Scent: None
Similar to other permethrin treatments, this product is formulated to treat clothing and outdoor equipment, providing a durable insect-repelling shield.

This spray, which has a 0.5 percent concentration of permethrin, is valued for its ability to keep a wide range of insects at bay from fabrics, contributing to an overall bug-free experience in outdoor environments. It creates a "kill zone" on treated gear, such as tents or sleeping bags, reducing the number of mosquitoes that can bite or remain nearby.

It’s completely odorless, so it will protect you without making gear smell, and it comes in a 6.5 ounce spray bottle. Users should spray outdoor gear and clothing in a well-ventilated area and wait 2-4 hours for it to be fully dry. Some users report seeing small white flecks fly into the air upon application, although they liquefy and absorb into the fabric once dry.

Best Device

Thermacell E-Series Rechargeable Mosquito Repeller

$32 at Amazon
$39.99Now 20% Off

Pros

  • Creates a scent-free and spray-free zone of protection, reducing the need for skin application
  • Rechargeable battery offers convenient portability and reuse
  • Quiet operation with no open flame or direct skin contact

Cons

  • Effectiveness can be reduced in windy conditions, as the repellent vapor disperses quickly
  • Only intended for stationary use in an area

Key Specs

  • Time effective: 12 hours per cartridge
  • Active Ingredient: Metofluthrin
  • Type: Vapor
  • Use: Outdoor Area
  • Scent: None

This innovative device creates a protective zone against mosquitoes, offering an alternative to traditional topical repellents. The device is a spatial repellent, meaning it protects an area rather than an individual.

This product operates by heating a repellent mat infused with metofluthrin, which is a synthetic insecticide.

 Once heated, it releases an invisible, odorless vapor that deters mosquitoes in a defined outdoor area.

We love that this device is user-friendly and that it features a rechargeable battery. Plus, each 12-hour metofluthrin liquid refill cartridge is easy to order and stock up on, ensuring your device is always ready to use throughout the summer on patios, backyards, and porches.

Comparison Chart

Superlative
Time Effective
Active Ingredient
Type
Use
Scent
Best with DEET
8 hours
DEET 25 Percent
Aerosol spray
Skin
Chemical and pungent
Best with DEET for Extra Protection
10 hours
DEET 98 Percent
Pump spray
Skin
Refined chemical
Best with Picaridin
12 hours
Picadin 20 Percent
Pump Spray
Skin
None
Best Oil of Lemon Eucalyptus Spray
6 hours
OLE/PMD 30 Percent
Pump spray
Skin
Refined chemical
Best for Kids
8 hours
IR3535 20 Percent
Aerosol spray
Skin
None
Best Wipes
7 hours
DEET 30 Percent
Wipes
Skin
Chemical
Best for Clothing
6 weeks or 6 washes
Permethrin 0.5 Percent
Non-aerosol spray
Clothing
None
Best for Gear
2 weeks
Permethrin 0.5 Percent
Aerosol spray
Gear
None
Best Device
12 hours per Cartridge
Metofluthrin
Vapor
Outdoor Area
None

How We Chose the Best Mosquito Repellents

We consulted with dermatologists to advise on the best mosquito repellents for your skin, clothing, gear, and outdoor areas, which contain only effective and safe ingredients approved by the CDC and EPA. These medical experts include:

  • Dr. Kseniya Kobets, Director of Cosmetic Dermatology at Montefiore Einstein Advanced Care in New York.
  • Dr. Hannah Kopelman, Chief Medical Officer at DermOnDemand, who practices in New York City and Palm Beach County, Florida.

What to Look for in a Mosquito Repellent

When shopping for a mosquito repellent, focus on the formula’s active ingredients and ensure that you only consider ingredients approved by the CDC and the Environmental Protection Agency (EPA). “The CDC only recommends ingredients shown to decrease disease transmission without skin irritation,” says Dr.Kobets. She notes that EPA-approved ingredients have been deemed safe for the environment, which is another factor to prioritize. Both Dr. Kobets and Dr. Kopelman offered their suggestions about what to look for in a mosquito repellent:

  • Effective active ingredients, such as Deet, picaridin, OLE/PMD, and permethrin (for clothing).
  • Single-use formulas. The CDC advises against using products that combine sunscreen with repellents, as they require different application frequencies.

  • Sprays are Dr. Kopelman’s favorite application method. “They’re easy to apply evenly and reapply throughout the day.”
  • Products that last at least six to eight hours are the gold standard to prevent over-application, according to Dr. Kobets.

Are Natural Mosquito Repellents Effective?

According to both doctors we interviewed, the botanical ingredient OLE/PMD is highly effective. The CDC confirms that OLE/PM is a key skin repellent against mosquitoes.

 Dr. Kopelman says that other natural alternatives aren't always safe because their ineffectiveness against mosquito-borne illnesses can become a public health risk.

When to Use Certain Mosquito Repellent Applications

The experts said that whether to use a spray, wipe, or spatial repellent depends on several factors. According to Dr. Kobets, “Sprays are great for full-body and clothing use.”

Dr. Kopelman explains, “Wipes can work well when you’re on the go or applying to kids, but I find they’re sometimes too light for high-exposure situations.”

Both Dr. Kopelman and Dr. Kobets say that spatial repellents are ideal for outdoor areas, rather than for individuals. 

Tips for Repelling Mosquitoes

According to the CDC, the most effective way to repel mosquitoes is to employ what it calls Integrated Mosquito Management (IMM).

 This approach involves multiple strategies for effective control and prevention. For example, you’ll want to use CDC- and EPA-approved ingredients in skin repellents in addition to wearing long-sleeved shirts, long pants, and socks to cover exposed skin during peak mosquito activity.

Finally, treating clothing and gear with permethrin and using a spatial repellent helps create a multi-faceted zone of protection, reducing the chance of contracting a vector-borne illness.

FAQs

What is the best way to repel mosquitoes?
According to our experts, the most effective ingredient against mosquitoes is DEET. The CDC also recommends creating a physical barrier against mosquitoes for a well-rounded approach to prevention.
According to the CDC, you should eliminate standing water where mosquitoes lay eggs; remove leaves and other yard waste that can collect water; and ensure windows and doors have intact screens without rips, tears, or holes to prevent mosquitoes from entering your home.
The CDC doesn’t list Citronella as a known repellent against mosquitoes. The most effective CDC-approved botanical ingredient is OLE/PMD. 

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Jill Di Donato

Author

Jill has over 15 years of experience writing about women's health, wellness, and beauty. She has deep knowledge of buzzy products and what makes them popular with consumers. She's tested hundreds of skin care products, tools, and medical aesthetics procedures throughout her career, and she has interviewed top dermatologists, plastic surgeons, and holistic physicians to stay on top of the latest in skin health and wellness.

Jill is the former associate editorial operations director of the beauty group at Dotdash Meredith, where she worked on brands such as Shape and Byrdie, editing health, fitness, skin care, wellness, and body care commerce content.

She's also a former sex and relationship writer, and has made national television appearances to discuss sexual wellness topics for women. In addition to anything beauty and sexual wellness, Jill specializes in writing about body neutrality and mental health.

Jill has a degree in sociology, with a focus on gender studies and she has taught sociology classes at Barnard and Columbia University.

Jacquelyn Dosal

Jacquelyn Dosal, MD

Medical Reviewer

Jacquelyn Dosal, MD, is a board-certified dermatologist practicing at The Dermatology House in Park City, Utah. Her areas of expertise include acne, rosacea, integrative treatments of inflammatory skin diseases, as well as laser treatment of the skin and injectables.

Dr. Dosal writes cosmetic questions for the certifying exams for the American Board of Dermatology. She is also the deputy editor for the American Academy of Dermatology's podcast, Dialogues in Dermatology.

Orlando de Guzman

Fact-Checker

Orlando de Guzman is a writer and editor with expertise in health and environmental news. He has a background in investigative and science journalism and has worked on documentary films about war and trauma, health, sanitation, and the changing climate around the world. His interest in health and medicine started after an early career as a medical and legal translator.

De Guzman is a longtime health and fitness enthusiast who is interested in nutrition, diet, and mental health. He participates in endurance sports and cross-trains in several traditions of martial arts from Southeast Asia. De Guzman is interested in how the progressively complex movements of martial arts training can improve cognition and mental well-being, especially for those with PTSD and for those approaching middle age and beyond.

De Guzman has a dual B.A. in communications and international studies from the University of Washington in Seattle. He is committed to factual storytelling and evidence-based reporting on critical choices that affect our planet.

Alexandra Klausner

Editor

Alexandra Klausner is a freelance health writer and editor with over 10 years of journalism experience. Prior to going freelance, she worked as a reporter and editor at the New York Post for eight years covering everything from health and wellness to features and breaking news. Before that, she covered multiple beats at the Daily Mail Online for three years.

Alexandra graduated from Skidmore College in Saratoga Springs with a bachelor's degree in theater. As a New York City native, she is also a grant-winning playwright, actor, freestyle singer, catchy-hook writer, and podcaster. She loves yoga, 5 Rhythms dance meditation, and running.

EDITORIAL SOURCES
Everyday Health follows strict sourcing guidelines to ensure the accuracy of its content, outlined in our editorial policy. We use only trustworthy sources, including peer-reviewed studies, board-certified medical experts, patients with lived experience, and information from top institutions.
Resources
  1. Current Dengue Outbreak. CDC. July 29, 2025.
  2. Ongoing Risk of Dengue Virus Infections and Updated Testing Recommendations in the United States. CDC. March 18, 2025.
  3. Coventry PA et al. Nature-based outdoor activities for mental and physical health: Systematic review and meta-analysis. SSM - Population Health. October 1, 2021.
  4. Chen-Hussey V et al. Assessment of methods used to determine the safety of the topical insect repellent N,N-diethyl-m-toluamide (DEET). Parasites & Vectors. June 3, 2014.
  5. DeGennaro M. The mysterious multi-modal repellency of DEET. Fly. August 7, 2015.
  6. Sluydts V et al. Efficacy of topical mosquito repellent (picaridin) plus long-lasting insecticidal nets versus long-lasting insecticidal nets alone for control of malaria: a cluster randomised controlled trial. The Lancet. Infectious Diseases. October 2016.
  7. Toxicological Profile for DEET (N,N-diethyl-meta-toluamide). Agency for Toxic Substance and Disease Registry.
  8. Yavasoglu SI et al. Novo plant-based mosquito repellent shows promise for exclusion of Aedes mosquitoes from “window” entry. Journal of Medical Entomology. January 13, 2025.
  9. aminopropionic acid, ethyl ester (IR3535). U.S. Environmental Protection Agency.
  10. Preventing Mosquito Bites. CDC.
  11. EPA-Registered Repellent Ingredients. California Dept. of Public Health.
  12. Evaporation Sensation. American Chemical Society - Chemistry For Life. Chemistry For Life. Evaporation Sensation. 2025.
  13. Saavedra-Rodriguez K et al. Permethrin resistance in Aedes aegypti: Genomic variants that confer knockdown resistance, recovery, and death. PLoS Genetics. June 17, 2021.
  14. Vang A et al. Evaluation of surface versus total permethrin content in permethrin-treated clothing: Implications for protection against mosquitoes. Pathogens and Global Health. January 17, 2022.
  15. Permethrin General Fact Sheet. National Pesticide Information Center.
  16. Bernier UR et al. A combined experimental-computational approach for spatial protection efficacy assessment of controlled release devices against mosquitoes (Anopheles). PLoS Neglected Tropical Diseases. March 11, 2019.
  17. Skin-Applied Repellent Ingredients. United States Environmental Protection Agency. January 29, 2025.
  18. Integrated Mosquito Management. CDC. April 20, 2024.