6 Causes of Bad or Strange Hand Odor, According to a Doctor

6 Reasons Your Hands Smell and How to Stop the Stink

6 Reasons Your Hands Smell and How to Stop the Stink
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Most of us bring our fingers or hands up to our faces countless times a day without even realizing it. But you might take notice if your hands have a funky odor.

Bad or weird hand smells are usually temporary and tend to clear up on their own. “Hands and fingernails tend to pick up odors simply because they’re touching different things,” says Miami-based board-certified dermatologist Anna Chacon, MD.

Some foods, drinks, and medications can lead to increased body odor in general — hands included. Less commonly, unpleasant smells can develop due to an underlying medical condition.

Here are six possible causes of hand odor and what to do about them.

1. You Touched Something Stinky

Pungent foods like onion or garlic have a strong sulfur smell that can linger on your hands after you handle them, Dr. Chacon says.

Contact odors typically go away on their own, but you might be able to speed up the process by rubbing your hands with a stainless-steel object (like a fork, spoon, or faucet) or a stainless-steel odor-absorbing bar, Chacon says.

Though studies haven’t looked closely at stainless steel’s deodorizing powers, it’s thought that lingering odors are transferred away from the skin when they bind to the steel’s molecules.

2. It’s Something You Ate or Drank

Strong-smelling foods or drinks — like garlic, onion, curries, and alcohol — don’t just tend to linger on your breath. Compounds from the foods can also be excreted through sweat glands that are present all over the body, including on your palms, says Beth Goldstein, MD, adjunct clinical professor of dermatology at the University of North Carolina at Chapel Hill. And when the sweat mixes with bacteria on your skin, you might start to get some funky whiffs.

You should notice the smell lessen as the food or drink passes farther into your digestive tract and eventually leaves your system. But if you want to stop your hands from reeking in the meantime, sudsing up with an antibacterial soap can help. Other options include cleaning your hands with:

  • White vinegar
  • Baking soda
  • Salt scrub
  • Lemon juice

With any hand-cleaning treatment, it’s important not to overdo it or scrub excessively, which can cause irritant dermatitis or tissue injury.

3. You Started a New Medication

Started a new prescription? Certain medications can cause you to sweat more heavily, which could potentially translate to more noticeable odor on your hands. These drugs include:

  • ‌Cholinesterase inhibitors‌ used to treat Alzheimer’s and dementia, including Aricept, Exelon, and Razadyne
  • ‌Opioids‌ used to treat pain, such as OxyContin, Percocet, and Vicodin
  • ‌Selective serotonin reuptake inhibitors‌ (SSRIs) used to treat depression and anxiety, including Lexapro, Prozac, and Zoloft
  • ‌Tricyclic antidepressants‌ used to treat conditions that include depression and OCD, such as Elavil, Norpramin, and Pamelor

Penicillin is another common culprit, Goldstein says. While it doesn’t make you sweat more, its compounds can still be excreted through sweat glands all over the body, causing an odor when the sweat mixes with your skin’s bacteria.

Washing with an antibacterial soap can help you combat odors caused by short-term meds like a course of penicillin. But if you’re dealing with hand odor caused by a drug that’s been prescribed for long-term use, talk to your doctor. It may be possible to adjust your dose or to try a different medication.

4. You’re a Heavy Sweater

If your palms seem perpetually plagued by smelly sweat or clamminess, you could have bromhidrosis. The disorder, characterized by excessive sweating, can cause hands or other parts of the body to have an unpleasant odor when the sweat mixes with naturally occurring bacteria on the skin.

Bromhidrosis isn’t caused by poor hygiene, but not washing often enough can make the problem worse. If the problem seems to affect your hands in particular, frequent sudsing with an antibacterial soap may be helpful.

You can also manage the sweating by using an antiperspirant on your palms.

 There are also pills that help to decrease sweating as well as topical treatments like Qbrexza wipes. In more severe cases, treatments like iontophoresis (a procedure that sends mild electric currents through the skin’s surface to reduce sweating) or Botox injections can also help. These would be prescribed by a dermatologist.

5. You Have Nail Fungus

Noticing a footlike smell on your hands? If the funk seems to linger around your nails in particular, you could be dealing with nail fungus, or what doctors call onychomycosis. “Oftentimes it smells like rotten cheese,” Chacon says.

Nail fungus is more likely to strike in the toenails, but it can affect fingernails, too. In addition to that foul smell, fungus-stricken nails might appear thick, yellow or whitish, brittle or crumbly, or have a distorted shape.

In some cases, an over-the-counter antifungal treatment can effectively fight the fungus, though it can take months to see results. Soaking in white vinegar is a common home treatment. But stubborn fungal infections might need prescription topical or oral antifungal drugs. A dermatologist can determine the best course of treatment for you.

6. You Have an Underlying Health Condition

Certain health problems can cause the entire body, including the hands, to give off an unusual odor. A sweet, fruity smell could be a sign of undiagnosed or poorly managed diabetes, while a “bleach” odor may indicate that a person has liver or kidney disease, Chacon says.

If you notice that your body and hands are emitting a foul, pungent odor like rotting fish or garbage, you could be dealing with trimethylaminuria, a metabolic disorder that occurs when the body is unable to break down trimethylamine, a chemical compound found in certain foods. When the trimethylamine builds up in the body, it can start to be emitted through a person’s sweat, urine, or breath.

Another condition that causes foul odors on the skin is pitted keratolysis. This most commonly occurs on the feet, but it can also affect the hands. It is caused by a bacterial infection due to risk factors like excessive sweating and occlusion, often from wearing rubber gloves or heavy-duty boots. In addition to a foul odor, common symptoms include tiny pits in the skin and a whitish discoloration in the affected area.

If you suspect a medical condition is behind your smelly hands, see your doctor, who can make a diagnosis and create a treatment plan. Pitted keratolysis is treated with a topical antibiotic to remove the bacteria.

There’s no cure for trimethylaminuria, but the smell can be managed by making dietary changes and taking vitamin B12, probiotic supplements, antibiotics, or activated charcoal.

The Takeaway

  • An unpleasant smell on your hands that sticks around for a day or two likely isn’t cause for concern, especially if you touched or ate something with a strong odor.
  • Aside from touching something, certain medications can cause excessive sweating, which can lead to body odor.
  • If you’re dealing with hand or body odor that you can’t explain or that doesn’t seem to be easing up, call your doctor. The intense smell could be a sign of an underlying medical condition that needs to be addressed.
EDITORIAL SOURCES
Everyday Health follows strict sourcing guidelines to ensure the accuracy of its content, outlined in our editorial policy. We use only trustworthy sources, including peer-reviewed studies, board-certified medical experts, patients with lived experience, and information from top institutions.
Resources
  1. Lorch M. Does Stainless Steel Remove the Smell of Garlic From Hands? BBC Science Focus.
  2. Common Drugs/Medications Known to Cause Diaphoresis Listed by Therapeutic Class. International Hyperhidrosis Society.
  3. Hodge BD et al. Anatomy, Skin Sweat Glands. StatPearls. October 10, 2022.
  4. Sweaty Hands. International Hyperhidrosis Society.
  5. Tips for Best Results — Rx. International Hyperhidrosis Society.
  6. Nail Fungus. Mayo Clinic. May 15, 2024.
  7. Body Odor. Cleveland Clinic. March 4, 2022.
  8. Trimethylaminuria. MedlinePlus. September 8, 2021.
  9. Pitted Keratolysis. Cleveland Clinic. June 17, 2022.
  10. Trymethylaminuria (Fish Odor Syndrome). Cleveland Clinic. April 5, 2024.
Jacquelyn Dosal

Jacquelyn Dosal, MD

Medical Reviewer

Jacquelyn Dosal, MD, is a board-certified dermatologist practicing at The Dermatology House in Park City, Utah. Her areas of expertise include acne, rosacea, integrative treatments of inflammatory skin diseases, as well as laser treatment of the skin and injectables.

Dr. Dosal writes cosmetic questions for the certifying exams for the American Board of Dermatology. She is also the deputy editor for the American Academy of Dermatology's podcast, Dialogues in Dermatology.

Marygrace Taylor

Marygrace Taylor

Author
Marygrace Taylor is a health writer and editor based in Philadelphia. Her work has appeared in publications including Parade, Glamour, Women's Health, Prevention, RedbookMen's Health, and O, The Oprah Magazine. She's also the coauthor of Eat Clean, Stay Lean: The Diet and Prevention Mediterranean Table.