10 Best Creams for Eczema We Found and Tested in 2025

The 10 Best Dermatologist-Approved Creams for Eczema

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As someone with eczema, I’ve often used lotions, creams, and ointments on various body parts, without giving much thought to the difference. But each type of eczema relief is unique, and they can be used strategically in different ways. “When lifestyle or patient preference doesn’t allow using an ointment, my next choice is cream. It can still be thick, moisturizing, and deliver medication,” says Jacquelyn Dosal, MD, a board-certified dermatologist at the Dermatology House in Park City, Utah.

“I like seeing ceramides in a cream — it’s hard to put them in ointment,” says Dr. Dosal. “They’re excellent at repairing the skin barrier.” Board-certified dermatologist Ruth McTighe, MD, of Waccamaw Dermatology in Mt. Pleasant, South Carolina, also cites ceramides as a key ingredient. “Always look for products with ceramides in them — ceramides help with the barrier function that’s lost with eczema,” she notes.

Eczema is far from a one-size-fits-all situation, but the hope is that you’ll find at least a few products that fit your needs. Here are our top picks for the best creams for eczema.

Our Top Picks for the Best Creams for Eczema

cream for eczema relief

Best for Face

Pacifica Vegan Ceramide Barrier Face Cream

Pros

  • Quick-absorbing texture ideal for wearing under makeup
  • Contains ceramides, shea butter, and oat kernel flour to moisturize
  • Niacinamide to soothe and hydrate
  • Free from fragrance, parabens, phthalates, sulfates (SLS), mineral oil
  • NEA Seal of Acceptance

Cons

  • Hydration may not last a full day
  • Sticky feeling

Key Specs

  • Notable ingredients: Vegan ceramides, niacinamide, oat kernel flour, shea butter, calendula
  • Face or body: Face
  • Scented: No
  • NEA Seal of Acceptance: Yes
Ceramides are formulated with ingredients that mimic the skin’s own natural moisturizing systems and can help repair the skin barrier.

Pacifica created vegan ceramides and paired them with ingredients like calendula, oat kernel flour, shea butter, and amino acids to help repair, moisturize, and soothe eczema-prone skin.

This cream also contains niacinamide, which is a type of vitamin B3. It can help boost hydration and calm redness, and it has been shown to help improve skin barrier function in eczema patients.

Pacifica Vegan Ceramide Barrier Face Cream is hydrating, absorbs quickly, and has a smooth, not oily, finish. It can be used as a night cream or in the morning under makeup, and a little goes a long way. As an added bonus, it’s packaged in a pretty glass jar that can be repurposed once it’s all been used.

Pacifica Vegan Ceramide Barrier Face Cream has the National Eczema Association’s (NEA) Seal of Acceptance, which means it’s undergone testing and review to determine that it’s free of ingredients that can trigger eczema or other skin irritations and is safe and gentle enough for use on eczema-prone skin.

Best for Hands

La Roche-Posay Cicaplast Hand Cream

$12.99 at Amazon

Pros

  • Water-resistant
  • Soothing for dry, itchy hands
  • Contains niacinamide, shea butter, and glycerin to moisturize
  • Fragrance-free and paraben-free
  • NEA Seal of Acceptance

Cons

  • High cost for a small amount of cream
  • Some may find it too thick

Key Specs

  • Notable ingredients: Niacinamide, shea butter, glycerin, dimethicone
  • Face or body: Body
  • Scented: No
  • NEA Seal of Acceptance: Yes

Ahh, hands. If only we didn’t have to use them so much, maybe they wouldn’t be so susceptible to eczema flares. As it is, though, our hands are on the front lines in terms of exposure to irritants, and for eczema patients, that often means that they are consistently dry, cracking, and in desperate need of moisture.

This hand cream answers the call. It’s made with niacinamide and shea butter, plus glycerin, which helps to repair cracked skin, and dimethicone, which softens dead skin cells.

 The brand also touts its use of “La Roche-Posay Thermal Spring Water,” which contains a combination of minerals, trace elements, and a high concentration of the natural antioxidant selenium.

 If that sounds like marketing speak to you (honestly, it did to me), take note: A 2018 study found that prebiotic thermal water can be a treatment option for inflammatory skin diseases.



La Roche-Posay Cicaplast Hand Cream can help soothe dry, cracked skin, and it stands up to frequent handwashing. Although the texture is very thick and even presents a bit like an ointment, it absorbs quickly and doesn’t leave your hands feeling greasy or sticky.

Best for Body

La Roche-Posay Lipikar AP+M Triple Repair Moisturizing Cream

$22.99 at Amazon

Pros

  • Contains ceramides, shea butter, and niacinamide for all-over hydration
  • Suitable for all skin types, including babies
  • Fragrance-free
  • NEA Seal of Acceptance

Cons

  • Packaging makes it difficult to access cream at the bottom
  • May leave slight residue

Key Specs

  • Notable ingredients: Ceramides, shea butter, niacinamide, glycerin, Vitreoscilla filiformis
  • Face or body: Body
  • Scented: No
  • NEA Seal of Acceptance: Yes
The “triple repair” in the name refers to rebalancing the skin’s microbiome, restoring the skin barrier, and replenishing the skin’s lipids. La Roche-Posay Lipikar AP+M Triple Repair Moisturizing Cream does all of the above with ceramides, shea butter, niacinamide, and glycerin. The last key ingredient is one we haven’t yet mentioned: postbiotic Aqua Posae Filiformis, also known as Vitreoscilla filiformis. Research shows that V. filiformis may have an impact on the skin similar to the way probiotics work in the gut; it can help modulate immunity and inflammation, stimulate skin defenses, and improve the skin barrier.


Put all those good ingredients together, and you get a rich cream that’s extremely hydrating and works fast to relieve the dry, cracked skin that results from eczema. The creamy texture spreads easily over large surface areas, like the legs and back. La Roche-Posay Lipikar AP+M Triple Repair Moisturizing Cream is even suitable for babies, as well as for patients who are undergoing chemotherapy and radiation.

Best for Daily Use

CeraVe Moisturizing Cream

$14.95 at Amazon
$20.49Now 27% Off

Pros

  • A little goes a long way; 19-ounce tub can last a long time
  • Contains ceramides, dimethicone, and hyaluronic acid to hydrate and moisturize
  • Fragrance-free
  • NEA Seal of Acceptance

Cons

  • May feel too thick for some
  • Not an ideal base for makeup

Key Specs

  • Notable ingredients: Ceramides, hyaluronic acid, dimethicone, petrolatum
  • Face or body: Body
  • Scented: No
  • NEA Seal of Acceptance: Yes

For an everyday moisturizer, you want something that’s dependable, long-lasting, and, ideally, budget-friendly. CeraVe Moisturizing Cream is just that. Unlike some more trendy options that come in small amounts, this is sold in a 19-ounce tub that’s perfect for popping on your dresser and dipping into every morning.

But it’s not just economical. CeraVe Moisturizing Cream is made with ceramides and dimethicone, as well as hyaluronic acid, which can help reduce itching and improve the skin barrier.

It’s also formulated with petrolatum, which is is another skin barrier-improving agent, more commonly seen in ointments.

Finally, as with all CeraVe products, it’s made with CeraVe’s proprietary MultiVesicular Emulsion technology, which the brand says is a structure of “time-released” spheres that provide multiple phases of moisturization. It’s nongreasy and leaves skin feeling soft. Although it’s thick, it absorbs quickly and works fast to help relieve dry, flaky skin.

Best With Hydrocortisone

CeraVe Hydrocortisone Anti-Itch Cream

$9.30 at Amazon
$9.79Now 5% Off

Pros

  • Contains cortisone to help relieve itchy skin fast
  • Includes ceramides, hyaluronic acid, and niacinamide to hydrate and moisturize
  • Fragrance-free
  • NEA Seal of Acceptance

Cons

  • Not for those who dislike using cortisone
  • Should not be used for more than seven consecutive days

Key Specs

  • Notable ingredients: 1 percent hydrocortisone, ceramides, hyaluronic acid, niacinamide
  • Face or body: Affected areas only
  • Scented: No
  • NEA Seal of Acceptance: Yes
If you have eczema, you know that sometimes hydrocortisone is the only thing that will do the trick in terms of relieving itchiness or tamping down a flare. The ingredient — which is a topical steroid — can help reduce swelling, redness, and itching, and it doesn’t require a prescription at a low dose.

There are a lot of 1 percent hydrocortisone options, and they all contain the same namesake ingredient. What sets them apart is what else is used in the formula. In this case, the cream also contains ceramides, hyaluronic acid, and niacinamide. In other words, in addition to a low-dose steroid, you’re also treating your skin with soothing, effective ingredients that will work to moisturize and repair your skin barrier. One more note on hydrocortisone: Be careful to apply it no more than four times a day, and for a maximum of seven consecutive days.

Best No-Frills

Vanicream Moisturizing Cream

$12.88 at Amazon
$16.43Now 22% Off

Pros

  • Gentle and lightweight
  • Free of fragrance, dye, lanolin, parabens, and formaldehyde
  • Nongreasy
  • NEA Seal of Acceptance

Cons

  • Contains propylene glycol, which can be an allergen
  • Pump can be difficult to use

Key Specs

  • Notable ingredients: Water, petrolatum
  • Face or body: Both
  • Scented: No
  • NEA Seal of Acceptance: Yes

I was first recommended Vanicream by a dermatologist in 2017. I hadn’t heard of it previously — after all, it’s not flashy or widely advertised — but when I began talking to other people with eczema about it, I learned that it’s generally a trusted and well-loved brand within that community.

Every product on this list is fragrance-free, but this cream is also free of lanolin, formaldehyde, and botanical extracts, all of which are common irritants.

It contains water and petrolatum, plus sorbitol (a humectant) and cetearyl alcohol (an emollient).

Vanicream Moisturizing Cream is gentle and moisturizing, and it is generally well tolerated by people with sensitive skin. It has a thick, creamy texture that feels lightweight once it’s absorbed. You can use it on both your face and body.

A quick note on propylene glycol: Propylene glycol is a humectant, which means that it helps moisturize your skin. But for some people, it can also be an allergen.

If propylene glycol has caused you irritation in other products, this one may not be right for you.

Best for Babies

Aveeno Baby Eczema Therapy Moisturizing Cream

$9.29 at Amazon
$13.34Now 30% Off

Pros

  • Gentle enough for babies’ skin
  • Contains 1 percent colloidal oatmeal, oat oil, and vitamin B5
  • Absorbs quickly
  • Free of fragrance, dyes, parabens, phthalates
  • NEA Seal of Acceptance

Cons

  • Oat smell may not be for everyone
  • Should not be used around the eyes

Key Specs

  • Notable ingredients: Colloidal oatmeal, oat oil, vitamin B5
  • Face or body: Both
  • Scented: No
  • NEA Seal of Acceptance: Yes

Having a baby with eczema is a unique kind of stress (my son had it when he was around 8 months old, and I recall it well). You’d do anything to keep their sweet little face clear and relieve their discomfort, and you also want to be sure that whatever you use to moisturize their skin is safe and gentle. That’s where Aveeno Baby Eczema Therapy Moisturizing Cream comes in.

This gentle cream is formulated with oat oil and colloidal oatmeal, which are both soothing and effective on dry, irritated skin.

It also contains vitamin B5, or panthenol, which is both a humectant and an emollient, meaning that it can draw water up from the lower levels of your skin to hydrate your top layer, and also use water from deep in your skin to fill in dry patches.

Our research shows that this product works well on babies and adults alike. It’s easy to apply and absorbs fast — a major pro when you take a wiggling baby into consideration — and it calms redness effectively. It doesn’t leave a sticky or greasy feeling, and it helps to keep little ones moisturized and clear.

Best Drugstore Buy

Eucerin Eczema Relief Cream

$12.97 at Walmart
$20.06Now 35% Off

Pros

  • Widely available in stores and online
  • Absorbs quickly for fast itch relief
  • Contains 1 percent colloidal oatmeal to help soothe itchy skin
  • Free of fragrance, dye, parabens
  • NEA Seal of Acceptance

Cons

  • Tube can be difficult to squeeze
  • Thick texture may not appeal to all

Key Specs

  • Notable ingredients: 1 percent colloidal oatmeal, glycerin, ceramide NP
  • Face or body: Both
  • Scented: No
  • NEA Seal of Acceptance: Yes
We’ve talked a lot about dryness, redness, and cracked skin, but we yet haven’t gotten into another major eczema symptom: itchiness.

The itch that comes with eczema can be one of the worst parts of the condition, and it can be particularly difficult to calm. Eucerin Eczema Relief Cream’s active ingredient is colloidal oatmeal, which, as we know, is great at repairing the skin barrier.

It also contains glycerin, as well as ceramide NP.

In our research, we found that eczema patients get real itch relief from this cream, and that — although it’s thick and takes some rubbing in order to absorb — it’s also effective at reducing redness from flares.

Best for Itch Relief

Gold Bond Eczema Relief Hand Cream

$4.72 at Amazon
$6.29Now 25% Off

Pros

  • Contains 2 percent colloidal oatmeal to help soothe itchy skin
  • Includes aloe, glycerin, dimethicone, and petrolatum to hydrate and moisturize
  • Free of fragrance, dye
  • NEA Seal of Acceptance

Cons

  • Slightly medicinal smell
  • Cream may pill on the skin

Key Specs

  • Notable ingredients: 2 percent colloidal oatmeal, aloe
  • Face or body: Body
  • Scented: No
  • NEA Seal of Acceptance: Yes
Gold Bond Eczema Relief Hand Cream contains 2 percent colloidal oatmeal as its active ingredient to help relieve itchy, dry skin. It also contains aloe, which can help retain skin moisture, as well as glycerin, dimethicone, and petrolatum.

We found that this hand cream helps with peeling, cracking skin all over, not just on your hands. That said, it is a particularly great cream to apply regularly to your hands — especially in colder months — and it leaves your skin feeling smooth and moisturized. And although it feels thick and heavy coming out of the tube, it absorbs well.

Best for Nighttime

Avène XeraCalm A.D Lipid-Replenishing Cream

$34.20 at Amazon
$38Now 10% Off

Pros

  • 48-hour hydration lasts overnight
  • Contains thermal spring water, glycerin, and mineral oil
  • Free of fragrance, parabens
  • NEA Seal of Acceptance

Cons

  • Most expensive cream on our list
  • Some people report an unpleasant smell

Key Specs

  • Notable ingredients: Avène thermal spring water, glycerin, mineral oil
  • Face or body: Both
  • Scented: No
  • NEA Seal of Acceptance: Yes
As an eczema sufferer, I know that it’s a great feeling to end the day by putting something soothing on your skin and knowing that you’ll wake up with less irritation. Enter: XeraCalm A.D Lipid-Replenishing Cream. Like La Roche-Posay, Avène has its own thermal spring water source, and there’s research that shows that it may provide protective properties for your skin.

This cream also contains glycerin and mineral oil, which can help moisturize the skin.

And it’s formulated with evening primrose oil, which may help improve skin dryness (although studies range from promising to inconclusive).

This cream provides long-lasting hydration and can quickly clear up eczema flares and stubborn patches. The texture is rich and velvety, and it feels appropriately luxe.

Comparison Table

Superlative
Notable Ingredients
Face or Body
Scented
NEA Seal of Acceptance
Best for face
Vegan ceramides, niacinamide, oat kernel flour, shea butter, calendula
Face
No
Yes
Best for hands
Niacinamide, shea butter, glycerin, dimethicone
Body
No
Yes
Best for body
Ceramides, shea butter, niacinamide, glycerin, Vitreoscilla filiformis
Best for body
No
Yes
Best for daily use
Ceramides, hyaluronic acid, dimethicone, petrolatum
Body
No
Yes
Best with hydrocortisone
1 percent hydrocortisone, ceramides, hyaluronic acid, niacinamide
For use on affected areas only
No
Yes
Best no-frills
Water, petrolatum
Both
No
Yes
Best for babies
Colloidal oatmeal, oat oil, vitamin B5
Both
No
Yes
Best drugstore buy
Colloidal oatmeal, glycerin, ceramide NP
Both
No
Yes
Best for itch relief
2 percent colloidal oatmeal, aloe
Body
No
Yes
Best for nighttime
Avène thermal spring water, glycerin, mineral oil
Both
No
Yes

How We Chose the Best Creams for Eczema

I’m a writer with more than a decade of experience writing about health, wellness, and lifestyle topics, and I’ve had eczema for my entire life. In addition to considering my firsthand experience with the condition, I read hundreds of product reviews and spoke to two dermatologists in order to come up with our picks for the best creams for eczema. I asked each expert about when they recommend creams for their patients (as opposed to lotions or ointments), and what ingredients they look for when recommending a cream.

I also asked them what ingredients they avoid in products (and specifically creams) for their eczema patients. I read studies to back up their recommendations and made sure that each product on this list met their criteria.

Here are the experts I consulted:

  • Jacquelyn Dosal, MD, a board-certified dermatologist at the Dermatology House in Park City, Utah
  • Ruth McTighe, MD, a board-certified dermatologist at Waccamaw Dermatology in Mt. Pleasant, South Carolina

What to Consider When Buying a Cream for Eczema

Products that are fragrance-free and don’t contain alcohol are important when shopping for creams for eczema. Eczema-friendly ingredients like ceramides, colloidal oatmeal, hyaluronic acid, glycerin, and niacinamide are always a plus. And remember: Look out for the NEA Seal of Acceptance. For a product to meet the NEA’s standards, it has to undergo testing by the NEA’s Scientific Oversight Committee for sensitivity, irritation, and toxicity. The committee also reviews the product’s ingredients and formulation data.

What Can Cause an Eczema Flare?

Eczema can flare for all kinds of reasons. Some potential triggers include dryness, a new irritant (such as a clothing material, makeup, skin-care product, or soap), smoke and pollutants, and stress.

On stress: When you’re stressed, your body is flooded with cortisol. That hormone can alter the production of skin oils, which can cause an eczema flare.

Do I Really Need a Different Cream for My Face and Body?

Facial eczema and eczema on the body are different: They have differences in skin microbiome, sebaceous gland concentration, and levels of natural moisturizing.

As a result, they do require different kinds of creams. Body creams are designed specifically for the skin on your body, and face creams are designed for the more sensitive skin on your face.

Are There Downsides to Using Steroid Creams?

The most common concern about topical steroid creams is that they can make the skin thinner. But studies have not found proof that this occurs if they are used correctly. “Used correctly” is key though. To avoid any unwanted side effects, you should work with your doctor to choose a steroid cream that’s suitable for the severity of your condition and the affected areas of your skin. The cream should be applied in a thin layer once a day, and it should be used until the flare-up is over.

FAQs

When is the best time to moisturize?
The best time to moisturize is after bathing or washing your hands. This will help to lock in the moisture and prevent water loss by strengthening the skin barrier.
“Ointment will always be the best in terms of efficacy, but you don’t always want to use ointments everywhere, and some people don’t like the way they feel,” says Dosal. So, although she always recommends ointments — which are better at locking in moisture and soothing skin — creams and lotions remain key components of an overall eczema regimen.
Eczema is not contagious between people, but yes, it can spread to other parts of your body. This can happen because of itching, which damages the skin and releases histamines, which then cause more itching and swelling in the skin. This is referred to as the “itch-scratch cycle.”

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Jana Pollack

Author

Jana Pollack is a freelance writer, editor, and creative strategist with significant experience writing about health, wellness, and lifestyle topics, including mental health, fitness, parenting, and food. She values conversational writing that puts the reader at ease while conveying real value, and always aims to leave the reader feeling calm and prepared to take action.

Previously, she worked for theSkimm and BuzzFeed in their branded content studios, and she has bylines at Romper, Insider, and Jenny Mag. Early in her career, she spent two years as an editorial assistant at UpToDate.

She lives in Boston with her husband and young son, and spends all of her free time reading.

Susan-Bard-bio

Susan Bard, MD

Medical Reviewer

Susan Bard, MD, is a clinical instructor in the department of dermatology at Weill Cornell Medicine and an adjunct clinical instructor in the department of dermatology at Mount Sinai in New York City. Her professional interests include Mohs micrographic surgery, cosmetic and laser procedures, and immunodermatology.

She is a procedural dermatologist with the American Board of Dermatology and a fellow of the American College of Mohs Surgery.

Dr. Bard has written numerous book chapters and articles for many prominent peer-reviewed journals, and authored the textbook The Laser Treatment of Vascular Lesions.

Daniel Oakley

Fact-Checker

Daniel Oakley is a journalist, editor, and fact-checker. He has written, edited, taught, and produced media for Dow Jones, S&P Global, IHS Markit, Third Coast Studios Magazine, and 826 National.

Oakley's path has always been a health-and-wellness-focused one. A competitive triathlete and racing fundraiser for the Leukemia and Lymphoma Society, he also spends summer weekends as an ISA-certified surf instructor and Red Cross professional water rescuer with Laru Beya Collective in Rockaway Beach, which helps kids master and delight in their own backyard — the ocean. It has taught Oakley that “optimizing body and mind” flourishes precisely at the wellspring of community.

Lili Ladaga

Lili Ladaga

Editor
Lili Ladaga is a freelance editor on the Marketplace Team at Everyday Health.
EDITORIAL SOURCES
Everyday Health follows strict sourcing guidelines to ensure the accuracy of its content, outlined in our editorial policy. We use only trustworthy sources, including peer-reviewed studies, board-certified medical experts, patients with lived experience, and information from top institutions.
Resources
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Additional Sources
  • Mack MR et al. The Itch-Scratch Cycle: A Neuroimmune Perspective. Trends in Immunology. December 2018.