Whey Protein and PCOS: Hormone Health Benefits and Dietary Tips

Can Whey Protein Reduce PCOS Symptoms?

Can Whey Protein Reduce PCOS Symptoms?
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Diet is considered a primary method of managing polycystic ovary syndrome (PCOS), according to Brown University Health.

Research on this hormonal condition supports the health benefits of low-glycemic carbohydrates and lean protein for managing blood glucose levels, according to Johns Hopkins Medicine.

Any nutrient is always best obtained from whole foods, but for people who can't (or prefer not to) rely on whole unprocessed foods, there are a variety of plant- and animal-based protein sources for PCOS. Whey has gained widespread popularity in the United States as a daily protein supplement, according to a 2024 review in Healthcare (Basel), though it is not without risks.

Here's what experts say about whether protein — and particularly whey — might improve symptoms of PCOS, and things to keep in mind while selecting a brand.

What Is PCOS?

PCOS is a hormone disorder that can cause hormonal imbalances, irregular periods, and cysts in the ovaries, according to the World Health Organization. It can also cause excess production of androgens like testosterone, which might cause symptoms like acne and excess facial hair.

Diet as a Treatment for PCOS

Diet is considered a primary and highly effective strategy for managing PCOS, because it directly addresses two conditions many people with PCOS experience: insulin resistance and chronic inflammation, according to Johns Hopkins Medicine.

Following certain diets has been shown to be an effective way to manage PCOS symptoms, according to a 2025 systemic review in Nutrients. Specifically, diets like the low-glycemic-index, Mediterranean, ketogenic, and high-fiber diets were helpful in improving insulin sensitivity, balancing hormones, and reducing inflammation.

Why Protein Is Important for PCOS

According to the review in Nutrients, protein plays an especially important role in the diet of someone with PCOS.

“[Because] people with PCOS generally have underlying dysfunction with the mechanisms of insulin action, it's advisable to follow a low-carb, higher-protein diet,” says board-certified reproductive endocrinologist, Rinku Mehta, MD, medical director of Kindbody Dallas.

“Any form of high-quality protein can be of benefit,” she adds. “Whey protein is a good source of protein for people with busy lifestyles who find it easier to add protein powder to a smoothie than to prepare and eat a high-protein meal.”

“PCOS people have insulin resistance related to elevated cortisol. Whey may be helpful in lowering cortisol levels,” says Kecia Gaither, MD, an ob-gyn and the director of perinatal services at NYC Health + Hospitals/Lincoln in New York City. “It may also reduce ghrelin — a hormone that increases the sensation of hunger. This ultimately impacts weight by lowering caloric intake. Weight loss can help normalize hormone levels of insulin and androgens, which are out of balance with PCOS.”

The Science on Whey Isn't Clear

Further research is needed to determine if whey protein is a particularly beneficial supplement for people with PCOS, says Sara Mucowski, MD, a board-certified reproductive endocrinologist at Dallas IVF.

‌“When it comes to whey protein and PCOS, the jury is still out,” says Dr. Mucowski. “There's been a lot of research in recent years trying to determine if there are beneficial effects of whey protein on the altered metabolic factors of women with PCOS. However, in those that do see benefits, supplementation is used for longer than 30 days.”

How to Choose a Brand

If you have PCOS and decide to try whey protein, look for a brand with a shorter ingredient list.

Dr. Mehta advises against using whey protein containing artificial additives or sweeteners, such as sugar or corn syrup.

EDITORIAL SOURCES
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John-Paul-McHugh-bio

John Paul McHugh, MD

Medical Reviewer

John Paul McHugh, MD, is an obstetrician-gynecologist and lifestyle medicine specialist in southern California. He has always placed wellness at the center of his work, in both delivering babies and improving practice standards. Dr. McHugh believes that bringing lifestyle medicine to the center of health and wellness empowers patients to make the change they seek and enjoy the benefits of true wellness.

He is a graduate of Harvard Medical School and the Massachusetts Institute of Technology and a fellow of the American College of Lifestyle Medicine. He served as a department chair at Scripps Mercy Hospital in San Diego and is now the chair-elect for the American College of Obstetricians and Gynecologists for California.

He has published several articles in the American Journal of Lifestyle Medicine and served as a peer reviewer for many articles. He contributed to the first textbook of lifestyle medicine in women's health: Improving Women's Health Across the Lifespan.

Corey Kagan Whelan

Corey Kagan Whelan

Author

Corey Kagan Whelan is a Brooklyn-based freelance writer and patient advocate working in reproductive health. She has previously designed educational programs for The American Fertility Association, Path2Parenthood and Family Equality Council. She writes health, wellness and medical content for a wide range of clients.