Can Vitamin B Complex Cause Yellow Stools?

Because B vitamins also affect your metabolism, taking excess vitamins in a B complex supplement may upset your digestive system and cause changes in your stools. Yellow stools may also indicate gastrointestinal problems, a possible side effect of taking too much vitamin B. If the problem persists, see your doctor.
Why Can Poops Turn Yellow?
Can Vitamin B Complex Change Your Stool Color?
But can B complex make poop yellow specifically? Perhaps indirectly if you take excessive amounts. This might be down to the side effects of niacin, or vitamin B3.
Other B Complex Side Effects and When to See a Doctor
- Diarrhea
- Facial redness
- Extreme tiredness
- Headache
- Nausea
- Upset stomach
- Bright yellow pee
- An allergic reaction, including rashes, itching, hives, and a swollen face, tongue, throat, or lips
- High blood sugar symptoms
- Other liver damage symptoms, including pain in the upper-right abdomen, appetite loss, dark yellow urine, a yellow tint in the skin or eyes known as jaundice, and feeling unusually weak or tired
- Tingly, numb, or painful feet
The Takeaway
- Taking a B complex supplement may alter stool color if you take excessive amounts, due to its adverse impact on the liver.
- If you have stool changes and other liver damage symptoms such as upper-right belly pain, extreme fatigue, and jaundice, promptly discuss these with a healthcare provider.
- Other common side effects of B complex supplements include diarrhea, bright yellow urine, facial redness, and nausea, but these are often not concerning unless persistent or severe.
- Always speak to a healthcare professional before starting to take a vitamin or mineral supplement.
- B Vitamins. MedlinePlus. September 23, 2021.
- Rana P et al. Prescribing vitamin B complex: Need for reassessment. Indian Journal of Medical Research. December 2021.
- Stool color: When to worry. Mayo Clinic. October 10, 2024.
- 4 Things That Cause Yellow Diarrhea. Cleveland Clinic. March 5, 2025.
- Vitamin B Complex Tablets or Capsules. Cleveland Clinic.
- Niacin. Office of Dietary Supplements. November 18, 2022.
- Stools - pale or clay-colored. Mount Sinai.
- Liver Damage Caused by Supplements Is Becoming More Common. Weill Cornell Medicine. June 25, 2025.
- Niacin Capsules and Tablets. Cleveland Clinic.
- Vitamin B complex. University of Rochester.

Yuying Luo, MD
Medical Reviewer
Yuying Luo, MD, is an assistant professor of medicine at Mount Sinai West and Morningside in New York City. She aims to deliver evidence-based, patient-centered, and holistic care for her patients.
Her clinical and research focus includes patients with disorders of gut-brain interaction such as irritable bowel syndrome and functional dyspepsia; patients with lower gastrointestinal motility (constipation) disorders and defecatory and anorectal disorders (such as dyssynergic defecation); and women’s gastrointestinal health.
She graduated from Harvard with a bachelor's degree in molecular and cellular biology and received her MD from the NYU Grossman School of Medicine. She completed her residency in internal medicine at the Icahn School of Medicine at Mount Sinai, where she was also chief resident. She completed her gastroenterology fellowship at Mount Sinai Hospital and was also chief fellow.

Kathryn Gilhuly
Author
Kathryn Gilhuly is a wellness coach based in San Diego. She helps doctors, nurses and other professionals implement lifestyle changes that focus on a healthy diet and exercise. Gilhuly holds a Master of Science in health, nutrition and exercise from North Dakota State University.