How Not to Get Sick With a Virus This Fall

“Fall and winter have been known for decades in the public health and medical community as cold and flu season,” says Robert H. Hopkins, MD, medical director of the National Foundation for Infectious Diseases. “Colds — which are mild upper respiratory infections caused by a number of different viruses — often are the first to be seen.” Viruses circulate very efficiently indoors, and viral illnesses spread more easily as chillier weather drives people inside.
On top of cold and flu, respiratory syncytial virus (RSV) also circulates in the Northern Hemisphere this time of year and cases of COVID-19 — which has multiple peaks year-round — increase as well, says Dr. Hopkins.
Get Vaccinated
"The best way to prevent influenza, COVID, and RSV is vaccination,” says Hopkins.
Vaccine Guidelines: Who Should Get the Shots?
“Vaccines vary depending upon age, existing medical conditions, previous vaccination status, and a number of other factors,” says Gina Koch, PhD, associate professor and director of graduate studies in nursing at Southeast Missouri State University in Cape Girardeau. “It is always best to discuss vaccination recommendations with your healthcare provider.”
- Flu Everyone 6 months and older should receive influenza vaccination every year. There are vaccines specifically formulated to protect older adults.
- COVID-19 The COVID vaccine may be given to anyone 6 months and older. “COVID can cause severe disease, hospitalization, and death in otherwise healthy people — so anyone who wants to reduce their risk of COVID should be vaccinated,” says Hopkins.
- RSV RSV vaccination is recommended in everyone 75 and older and in adults as young as 50 with chronic heart and lung disease or other medical conditions placing them at increased risk for severe RSV disease. Pregnant women may be vaccinated in the third trimester in order to pass on antibodies to protect their babies. Babies born between October and March and who will be less than 8 months old in this time whose mothers were not vaccinated should receive a long acting monoclonal antibody to prevent severe RSV disease.
In general, vaccinations are considered most vital to certain vulnerable groups:
- The very young (who do not have fully developed immune systems)
- The elderly (who don’t have immune systems that work as well as when they were younger)
- Individuals undergoing chemotherapy or taking other medications that weaken the immune system
- Those with chronic conditions (such as asthma, heart disease, and diabetes)
There is currently no vaccine to prevent the common cold, notes Dr. Koch.
“There are too many types of viruses that can cause a cold, and they mutate rapidly,” she says. “It would be impossible to identify and develop a vaccination to prevent them all.”
Wash Your Hands and the Surfaces You Touch
- Cover your mouth and nose when you cough or sneeze. Do not cough or sneeze into your hands. Try to use a tissue, and if not available, cough or sneeze into your elbow or the crook of your arm.
- Wash your hands regularly. Scrub your hands with soap and water for at least 20 seconds.
- Clean commonly touched surfaces. Use household cleaners that contain soap or detergent to kill germs on surfaces. “Keep in mind that antibacterial soaps and cleaners have no benefit over regular soaps and cleaners with regard to respiratory viruses,” Koch says.
- Improve indoor air quality. You can help eliminate airborne virus particles indoors by opening windows, using exhaust fans, or filtering air with portable HEPA filters.
If Someone You Live With Is Sick, Get Them Tested — and Keep Your Distance
If someone in your household has symptoms such as fever, chills, fatigue, cough, runny nose, and headache, testing for respiratory viruses can help determine what to do next.
For instance, if they are ill with the flu, an antiviral medicine can reduce their risk of severe illness and lower the odds they’ll infect you or someone else they cohabit with.
While a healthcare provider or community health center can conduct testing, at-home tests have made the process easier. Separate and combined tests for COVID and flu are available over the counter, but there is currently no commercially available at-home test for RSV.
Can Vitamins, Supplements, or Other Natural Remedies Help?
No vitamin or supplement has been shown conclusively to reduce the risk or severity of respiratory infection, and if taken in too large of a dose, some can in fact, be harmful, according to Koch.
A few supplements, however, have demonstrated some possible protective effects. These include:
- Vitamin C Vitamin C may have a minor role in reducing the duration of cold symptoms in adults, although numerous studies suggest the clinical importance of this is likely small, says Koch.
- Elderberry Elderberry is a dietary supplement for immune health. Some evidence suggests it could reduce the duration and severity of respiratory viral symptoms, but overall the evidence is inconclusive.
- Zinc Zinc is known to support the immune system, but Mayo Clinic says there’s no guarantee it will help you feel better faster. Studies have been conflicting, with some showing zinc to shorten how long people have viral symptoms, while others finding no effect.
For a natural way to help protect against viruses, Hopkins encourages three lifestyle strategies: healthy eating, adequate sleep, and regular exercise. All can support your overall health and keep your immune system in top form.
What About Masking?
Because viral droplets can circulate in the air, masking can certainly help protect against infection. The CDC says that masking can provide an extra layer of protection, especially in settings where people are closely confined and illnesses easily spread (like crowded buses, concerts, and classrooms).
Masking is largely a personal choice. If you are at high risk of complications from a viral illness like COVID-19 because of your age or a medical condition you have, or you live with someone who is at high risk, it’s reasonable to mask in certain scenarios even if you are in the minority. If you’re sick yourself, masking can be particularly helpful for protecting others, both close contacts and the general public.
Hopkins warns that masks may do little good if not worn correctly. “A mask must be worn consistently and fit well over the mouth and nose,” he says.
When to See a Doctor
Hopkins urges people to contact their healthcare professional if they are ill with the following symptoms:
- Can’t control a high fever with medication
- Can’t keep fluids down
- Have breathing difficulty
- Are older or have chronic health conditions
If viral symptoms come back after going away, that may also indicate the need to visit a doctor, according to Koch.
“Sometimes an individual will get sick, and then start to get over their symptoms, but not completely,” she says. “Then they may start to feel ill again, and maybe even develop a fever. This can be a sign of a secondary bacterial infection and may occur when a patient’s immune system is a bit beat down from fighting a virus. This would be a good time to see your healthcare provider for an evaluation.”
The Takeaway
- Vaccines are not 100 percent effective against respiratory diseases like the flu, COVID-19, and RSV, but they lower the odds of getting sick considerably and are highly protective against serious illness.
- Washing your hands regularly and sanitizing high-touch surfaces can help keep viruses at bay.
- Testing someone in your household who is unwell and keeping your distance from them if they have a contagious respiratory illness can help you avoid getting sick too.
- Masking can be a wise move if you are at high risk of severe illness from a respiratory infection or want to avoid spreading a virus to others.
Resources We Trust
- Mayo Clinic Germs: Understand and Protect Against Bacteria, Viruses, and Infections
- Cleveland Clinic Protecting Yourself from RSV
- National Foundation for Infectious Diseases Infectious Diseases
- American Lung Association Protecting Yourself This Respiratory Virus Season
- American Medical Association Prepare your Clinics and Patients for Fall and Winter Respiratory Virus Season
- 2025-2026 Respiratory Disease Season Outlook. Centers for Disease Control and Prevention. August 25, 2025.
- Seasonal Flu Vaccine Basics. Centers for Disease Control and Prevention. September 14, 2024.
- Immunizations for Respiratory Viruses Prevention. Centers for Disease Control and Prevention. August 18, 2025.
- O’Halloran, A, et al. Influenza-Associated Hospitalizations During a High Severity Season — Influenza Hospitalization Surveillance Network, United States, 2024–25 Influenza Season . Centers for Disease Control and Prevention. September 11, 2025.
- Preliminary Estimated Flu Disease Burden 2024-2025 Flu Season. Centers for Disease Control and Prevention. May 9, 2025.
- U.S. Vaccine Recommendations. National Foundation for Infectious Diseases.
- Leung, Nancy. Transmissibility and Transmission of Respiratory Viruses. Nature Reviews: Microbiology. March 22, 2021.
- Huillier AG et al. Survival of Rhinoviruses of Human Fingers. Clinical Microbiology and Infection. December 11, 2014.
- Preventing Respiratory Illnesses. Centers for Disease Control and Prevention. August 18, 2025.
- About Handwashing. Centers for Disease Control and Prevention. February 16, 2024.
- Preventing Spread of Respiratory Viruses When You're Sick. Centers for Disease Control and Prevention. August 18, 2025.
- Common Colds: Research Summaries – Does Vitamin C Prevent Colds? InformedHealth.org. December 11, 2023.
- Wieland L et al. Elderberry for Prevention and Treatment of Viral Respiratory Illnesses: A Systematic Review. BMC Complementary Medicine and Therapies. April 7, 2021.
- Zinc for Colds: The Final Word? Mayo Clinic. April 30, 2025.
- Science M et al. Zinc for the Treatment of the Common Cold . Canadian Medical Association Journal. July 10, 2012.

Jane Yoon Scott, MD
Medical Reviewer
Jane Yoon Scott, MD, is an infectious disease physician and an assistant professor of medicine at Emory University in Atlanta. Dr. Scott enjoys connecting with her patients, empowering them to understand and take ownership of their health, and encouraging them to ask questions so that they can make informed and thoughtful decisions.
She graduated with the highest honors from the Georgia Institute of Technology, then received her MD from the Medical College of Georgia. She completed her internal medicine residency training and chief residency at Temple University Hospital, as well as a fellowship in infectious diseases at Emory University. She is board-certified in both internal medicine and infectious diseases.
When she is not seeing patients, Dr. Scott works with neighboring health departments to promote public health, especially to communities that have been historically underserved. She also teaches medical trainees and lectures medical students at the Emory University School of Medicine.
In her free time, Dr. Scott appreciates a good coffee shop, weekend hikes, playing guitar, strolling through cities, sampling restaurants, and traveling to new places.

Don Rauf
Author
Don Rauf has been a freelance health writer for over 12 years and his writing has been featured in HealthDay, CBS News, WebMD, U.S. News & World Report, Mental Floss, United Press International (UPI), Health, and MedicineNet. He was previously a reporter for DailyRx.com where he covered stories related to cardiology, diabetes, lung cancer, prostate cancer, erectile dysfunction, menopause, and allergies. He has interviewed doctors and pharmaceutical representatives in the U.S. and abroad.
He is a prolific writer and has written more than 50 books, including Lost America: Vanished Civilizations, Abandoned Towns, and Roadside Attractions. Rauf lives in Seattle, Washington.