The Dos and Don’ts of Hepatitis C Treatment

Thanks to recent advances in medication, hepatitis C — a viral infection that affects the liver — is now highly treatable. But you still have to do your part, which means following a few important recommendations. Here are some things to do or avoid during hepatitis C treatment.
1. Don’t take other medications unless you’ve talked to your doctor first.
Many drugs can interfere with your hepatitis C medications, so it’s important to tell your doctor exactly what you’re taking or thinking about adding to your regimen, says James J. Lee, MD, a gastroenterologist and medical director at the James J. Lee, MD Center of Excellence for Digestive Health in Orange, California. This includes medicines used for acid reflux, an enlarged prostate, birth control, high cholesterol, and seizures.
What’s more, some drugs can be hard on your liver, including over-the-counter pills such as acetaminophen. If you need treatment for more than one health condition, work closely with your doctors, including your primary care physician and your gastroenterologist or hepatologist, to determine the best methods.
2. Don’t take vitamins and supplements without talking to your doctor.
Dietary supplements haven’t been shown to be effective treatments for hepatitis C, according to the National Center for Complementary and Integrative Health, and some may even have harmful side effects and interact poorly with medications. If you take vitamins or supplements, or are considering taking them for other health reasons, make sure your doctor knows. In some cases, your doctor may recommend a particular brand or suggest a different approach if the potential interactions or risks are too high.
3. Do follow your doctor’s exact instructions for treatment.
For hepatitis C medications to be effective, they need to be taken as prescribed. Missing doses increases the risk of the virus becoming resistant to medications, according to the American Liver Foundation. If you have side effects that make it difficult to take your medication, share this information with your doctor so they can make adjustments to your treatment plan.
4. Do communicate often with your doctor.
The treatment for hepatitis C has evolved over the years and may continue to change as new drugs come on the market, Dr. Lee says, which is why it’s so important to keep communicating with your doctor. Although you’ll be closely monitored during treatment, speak up about any difficulties or side effects you’re experiencing. Physical exams and blood tests are only part of the treatment equation. Your personal experience adds vital information so your doctor can provide you with the best treatment.
5. Don’t drink alcohol.
Alcohol is processed through the liver as a toxin and can be a source of inflammation in the organ, just like hepatitis C. When you’re undergoing treatment, it’s counterproductive to drink alcohol, Lee says, because it blunts the immune response to the virus and increases the severity of liver damage, making the treatment less effective.
6. Do talk to your doctor if you (or your partner) are pregnant or planning to become pregnant.
If you’re taking ribavirin to treat your hepatitis C, you should be aware that the drug carries a risk for birth defects, so it shouldn’t be used by pregnant people, people who plan to become pregnant, or people with partners who are pregnant or planning to become pregnant, Lee says. In addition, the risk of birth defects resulting from the use of newer curative drugs known as direct-acting antivirals (DAAs) is also unclear.
In fact, the threat is so serious that two forms of birth control are recommended while a person undergoes hepatitis C treatment and for six months after treatment is finished, according to the American Association for the Study of Liver Diseases and the Infectious Diseases Society of America.
It’s also important to note that the safety of ribavirin in breast milk has not been tested, so women should avoid breastfeeding while taking this medication. If you’re thinking about becoming pregnant or breastfeeding, talk to your doctor first.
7. Don’t breathe in toxic fumes from paint, cleaners, or other harsh chemicals.
When you’re treating hepatitis C, it’s important to stay away from toxins that could harm your liver, Lee says. Exposure to fumes can damage your liver cells, leading to an accumulation of fats (steatosis) in the liver, liver cell death, cirrhosis, and liver cancer, he says.
There’s a long list of potentially noxious chemicals and volatile organic compounds (VOCs), and some are common around the home and workplace, such as vinyl chloride (pipe sealant), carbon tetrachloride (adhesives), methylene chloride (paint removers), and glycol ethers (glass cleaners, floor cleaners, oven cleaners), Lee says.
VOCs can also be found in spot removers, fabric or leather cleaners, PVC cement and primer, glue removers, aerosol spray products for some paints, leather treatments, pesticides, and air conditioner refrigerant.

Justin Laube, MD
Medical Reviewer
Justin Laube, MD, is a board-certified integrative and internal medicine physician, a teacher, and a consultant with extensive expertise in integrative health, medical education, and trauma healing.
He graduated with a bachelor's in biology from the University of Wisconsin and a medical degree from the University of Minnesota Medical School. During medical school, he completed a graduate certificate in integrative therapies and healing practices through the Earl E. Bakken Center for Spirituality & Healing. He completed his three-year residency training in internal medicine at the University of California in Los Angeles on the primary care track and a two-year fellowship in integrative East-West primary care at the UCLA Health Center for East-West Medicine.
He is currently taking a multiyear personal and professional sabbatical to explore the relationship between childhood trauma, disease, and the processes of healing. He is developing a clinical practice for patients with complex trauma, as well as for others going through significant life transitions. He is working on a book distilling the insights from his sabbatical, teaching, and leading retreats on trauma, integrative health, mindfulness, and well-being for health professionals, students, and the community.
Previously, Dr. Laube was an assistant clinical professor at the UCLA Health Center for East-West Medicine and the David Geffen School of Medicine at UCLA, where he provided primary care and integrative East-West medical consultations. As part of the faculty, he completed a medical education fellowship and received a certificate in innovation in curriculum design and evaluation. He was the fellowship director at the Center for East-West Medicine and led courses for physician fellows, residents, and medical students.

Mikel Theobald
Author
Mikel Theobald is an Indianapolis-based freelance writer who covers a wide range of topics, including early childhood education, home and family, Olympic sports, nutrition, fitness, and health. Her work has appeared in consumer and professional publications such as HealthDay, AOL, Huffington Post, Livestrong, and others.
Her favorite aspect of health writing is providing information to readers that helps them confidently advocate for their health and well-being. She helps readers sort through the complexities of important topics so they walk away with a deeper understanding of the information.
When she isn’t spending time with her family or meeting a writing deadline, you can often find Theobald volunteering for child advocacy organizations. She is the proud mother of 3 humans, 2 dogs, and 1 cat. She loves good books, live music, and Broadway musicals.
- Hepatitis C and Dietary Supplements. National Center for Complementary and Integrative Health. May 2018.
- Treating Hepatitis C. American Liver Foundation. May 1, 2023.
- HCV in Pregnancy. HCVGuidelines.org. October 24, 2022.