Why Are You Sore in Your Left Arm — but Not Your Right Arm — After a Workout?

Why You’re Sorer in One Arm After a Workout
1. You Have a Muscle Imbalance
If you have arm soreness in one limb but not the other, it could be due to a muscle imbalance. Your weaker side may become sore from trying to keep up with your stronger side, as it has to work harder to complete the same amount of work. That leads to more muscle breakdown.
2. You Have a Muscle Strain or Other Injury
If you feel pain — not just soreness — in one arm, you may have injured it. Muscle strains, sprains, and tendonitis are all common workout injuries that could be the culprit of pain in one arm.
Muscle Strain
- Pain
- Weakness
- Muscle spasms
- Bruising
- Swelling
Treatment includes resting, icing, compressing, and elevating your strained muscle for a few days. You can also use over-the-counter nonsteroidal anti-inflammatory drugs (NSAIDs), like aspirin or ibuprofen (Advil), as a pain reliever for sore muscles.
Muscle Sprain
- Hearing or feeling a pop
- A reduced ability to move the joint near the sprain
- Pain
- Swelling
- Bruising
Tendinitis
- Pain that may feel like a dull ache during movements
- Tenderness
- Mild swelling
Tendinitis may take a few months to fully heal, and physical therapy may be beneficial during this time.
You can help prevent tendonitis by warming up your muscles before each workout. Also, avoid doing repetitive movements, suddenly increasing the amount or intensity of your training, or placing too much stress on your tendons.
In severe cases, heart attack
Other symptoms can include:
- Chest pain
- Shortness of breath
- Nausea or vomiting
- Lightheadedness or dizziness
- Sweating
- Coughing or wheezing
- Overwhelming anxiety (like a panic attack)
If you have any of these symptoms, get medical care right away.
How to Prevent Single-Arm Muscle Soreness
1. Delve Into Dumbbells
If you’re used to doing an upper-body workout consisting of bench presses, machine shoulder presses, barbell rows, chin-ups, and barbell curls, for instance, try switching to dumbbell chest presses, dumbbell shoulder presses, dumbbell rows, single-arm pull-downs, and dumbbell curls.
2. Focus Extra Exercise on Your Weak Side
3. Fix Your Form
You might use poor form when training your weaker side, which leads to the stronger side feeling sore after the workout.
The Takeaway
- Uneven soreness in your arms after a workout may be due to muscle imbalances, emphasizing the need to target weaker muscles with specific exercises to gradually balance your strength.
- After sustaining a strain or sprain, use rest, ice, compression, and elevation or over-the-counter pain relief medications to ease the pain.
- Besides warming up properly to help prevent future injuries, use dumbbells instead of barbells for an even and individualized focus. Always use proper form to help avoid imbalances or injuries.
- Muscle Soreness After a Workout: Can It Be Prevented? Houston Methodist. September 8, 2021.
- Jameson TSO et al. Muscle Damaging Eccentric Exercise Attenuates Disuse-Induced Declines in Daily Myofibrillar Protein Synthesis and Transiently Prevents Muscle Atrophy in Healthy Men. American Journal of Physiology: Endocrinology and Metabolism. November 8, 2021.
- Overactive Versus Underactive Muscles: What Does It All Mean? National Academy of Sports Medicine.
- Muscle Strain. Cleveland Clinic. February 18, 2025.
- Sprains. Mayo Clinic. October 27, 2022.
- Tendinitis. Mayo Clinic. Nov. 11, 2022.
- Symptoms - Heart Attack. National Health Service. July 13, 2023.
- This or That: Dumbbells vs Barbells. BreatheStrong CF.
- Barbell Bicep Curl. National Academy of Sports Medicine.
- Exercise and Strength Training With Arthritis. Arthritis Foundation. April 30, 2024.

Scott Haak, PT, DPT, MTC, CSCS
Medical Reviewer
Scott Haak, PT, DPT, has been a member of the Mayo Clinic staff since 2000. Dr. Haak serves as faculty for the Sports Medicine Fellowship program at Mayo Clinic Florida. He is certified by the NSCA (National Strength and Conditioning Association) as a CSCS (Certified Strength and Conditioning Specialist), is a Certified USA Weightlifting Coach and Certified USA Football Coach, and possesses a MTC (Manual Therapy Certification) from the University of St. Augustine for Health Sciences.
Haak is an exercise enthusiast and enjoys running, weightlifting, and sports performance training. He is the president and director of coaching of a youth tackle football organization, JDL Providence Football, and currently coaches high school football and weight lifting.

Adam Felman
Author
As a hearing aid user and hearing loss advocate, Adam greatly values content that illuminates invisible disabilities. (He's also a music producer and loves the opportunity to explore the junction at which hearing loss and music collide head-on.)
In his spare time, Adam enjoys running along Worthing seafront, hanging out with his rescue dog, Maggie, and performing loop artistry for disgruntled-looking rooms of 10 people or less.