Stay Away From These Nightshade Vegetables if You Have a Sensitivity

In some wellness circles, nightshade vegetables and fruits often appear on lists of “foods to avoid” if you have certain autoimmune conditions, including inflammatory bowel disease, psoriasis, and some kinds of arthritis.
However, if you have one of these conditions, know that avoiding nightshades is more precautionary or anecdotal than evidence-based.
While these foods haven’t been proven to cause inflammation, according to Cleveland Clinic, some people do find their symptoms improve if they eat less of them. Just like with any food, it’s possible to have a sensitivity or intolerance to nightshades.
But what exactly falls under the category of nightshades? These vegetables and fruits belong to the Solanaceae plant family, according to Colorado State University. This family contains more than 2,000 species that are widely used as food and medicine.
Below is a list of common nightshade vegetables and fruits that may be helpful to avoid if you have a sensitivity.
These foods have a lot of important nutrients. Before trying an elimination diet, work with your doctor or a registered dietitian to ensure you still get all the nutrients you need.
Potatoes
Potatoes are part of the nightshade family. This includes any potato with white or yellow flesh, regardless of the color on the outside, according to Cleveland Clinic.
If you have a sensitivity to nightshades, avoid the obvious foods made from potatoes like mashed potatoes and french fries, but also be sure to read ingredient lists on processed foods to avoid potatoes.
Sweet potatoes, which are in a different botanical family, make a good swap.
Tomatoes
Another widely consumed member of the nightshade family is the tomato, according to Colorado State University. Although people often refer to the tomato as a vegetable, scientifically, it falls into the category of fruit.
If you have a nightshade sensitivity, it’s best to avoid all raw tomatoes and cooked tomatoes in foods like pasta sauce and ketchup.
Be sure to read the ingredient lists on soups and condiments such as hot sauces, barbecue sauces, and marinades, because they often contain tomatoes.
Peppers
Peppers belong to the Solanaceae family, too, although they’re in a different genus than other nightshades, according to the University of South Florida. This includes common ingredients like bell peppers, jalapeños, habaneros, cayenne peppers, and paprika.
Be sure to read labels and communicate well with servers and chefs when eating out to avoid the ingredient.
Black pepper and peppercorns come from a different botanical family and are not nightshades, according to the U.S. Department of Agriculture.
Eggplant
Eggplant is a nightshade native to South Asia, according to the University of Florida, but it appears in cuisines from many different parts of the world.
If you’re ordering a meal that contains mixed vegetables, be sure to tell your server that you cannot eat eggplant and other nightshades. When in doubt, it’s best to avoid a food or dish altogether if you have an allergy or sensitivity.
Tomatillos
Tomatillos, another member of the nightshade family, are often used in Mexican cuisine in dishes like chile verde and salsa verde.
Tomatillos have a papery husk. The fruit hangs like small round paper lanterns from the plant. Tomatillos are typically picked when they are still green and used to lend a citrusy tartness to dishes, according to Utah State University.
Goji Berries
Goji berries fall into the nightshade family, too. These slightly sweet red berries, sometimes called wolfberries, are native to Asia, according to Utah State University.
Goji berries can be eaten raw, dried, or made into a juice. They’re easy nightshades to avoid, but be sure to read the ingredient list of juices, smoothies, teas, and nutritional supplements to be sure they don’t contain goji berries.
Another edible berry in the nightshade family, according to Cleveland Clinic, is the golden berry, also known as a Peruvian ground cherry or cape gooseberry.
- University of California in San Francisco: "Sweet Potato: Part of the Yamily?"
- Colorado State University: "Nightshades and Your Health"
- Cleveland Clinic: “The Truth About Nightshades: Are They Bad for You?”
- Colorado State University: “6 Facts You Didn't Know About Nightshades”
- Cleveland Clinic: “Arthritis: Should You Avoid Nightshade Vegetables?”
- Atlas of Florida Plants: “Solanaceae"
- U.S. Department of Agriculture: “Piper nigrum L.”
- University of Florida: “Eggplant”
- Utah State University: “How to Grow Tomatillos in Your Garden”
- Utah State University: “How to Grow Goji Berries in Your Garden”
- Cleveland Clinic: “Are Golden Berries Good for Your Health?”

Kayli Anderson, RDN
Medical Reviewer
Kayli Anderson has over a decade of experience in nutrition, culinary education, and lifestyle medicine. She believes that eating well should be simple, pleasurable, and sustainable. Anderson has worked with clients from all walks of life, but she currently specializes in nutrition therapy and lifestyle medicine for women. She’s the founder of PlantBasedMavens.com, a hub for women to get evidence-based, practical, and woman-centered guidance on nutrition and cooking, hormone health, fertility, pregnancy, movement, mental well-being, nontoxic living, and more.
Anderson is board-certified in lifestyle medicine and serves as lead faculty of the American College of Lifestyle Medicine’s (ACLM) "Food as Medicine" course. She is past chair of the ACLM's registered dietitian member interest group, secretary of the women's health member interest group, and nutrition faculty for many of ACLM's other course offerings. She is the coauthor of the Plant-Based Nutrition Quick Start Guide and works with many of the leading organizations in nutrition and lifestyle medicine to develop nutrition content, recipes, and educational programs.
Anderson frequently speaks on the topics of women’s health and plant-based nutrition and has coauthored two lifestyle medicine textbooks, including the first one on women’s health, Improving Women's Health Across the Lifespan.
She received a master's degree in nutrition and physical performance and is certified as an exercise physiologist and intuitive eating counselor. She's a student of herbal medicine and women's integrative and functional medicine. She lives with her husband in the Colorado Rocky Mountains, where you’ll find her out on a trail or in her garden.
Erin Mosbaugh
Author
Erin has made telling stories about food her profession. You can find those stories in Food & Wine, LA Weekly, Serious Eats, Robb Report, Complex Magazine and Everydayhealth.com. Did we mention she's an Angeleno? Third generation, players.