Can Gluten Intolerance Cause Mucus in Stool?

You may not have celiac disease — an autoimmune disorder triggered by consuming the gluten protein in wheat, barley, and rye — but it’s possible you have gluten intolerance.
Although it’s not a hallmark symptom of gluten intolerance, another part of that shift could be the presence of mucus, a clear and jelly-like substance, in your stool.
That’s because gluten intolerance could cause changes in your bowel habits, which may include increased mucus production in stool, says Nayana George, MD, a gastroenterologist at Orlando Health Digestive Health Institute in St. Petersburg, Florida.
A small amount of mucus in stool occasionally, such as the day after you eat gluten but not in your stool usually, is likely not a cause for concern. But pay attention to whether you’re having other symptoms, such as fever or chills, that may indicate a more serious issue, she says.
Here’s a look at why mucus may occur with gluten intolerance, other reasons you may see mucus, and when to consider checking in with your healthcare provider.
Mucus in Stool: Is It a Sign of Gluten Intolerance?
The mucous membrane, also called the mucosa, in your digestive system is a lining that protects your intestines from harmful substances while still letting nutrients and water absorb into the bloodstream.
When there’s disruption in the mucosa from inflammation, damage, or infection, that can cause an increase in mucus production to fight what the body sees as a threat.
When that happens, more of the mucus is shed through bowel movements, says Richard Terry, DO, family medicine physician and associate dean of academic affairs at Lake Erie College of Osteopathic Medicine in Elmira, Pennsylvania.
“Mucus in the stool can occur in individuals with gluten intolerance, though it is not one of the classic hallmark symptoms of that condition,” he says. It’s important to note, though, that this usually happens along with other bowel habit changes.
Other Causes of Mucus in Stool
Gluten intolerance isn’t the only potential cause of mucus in stool. Here are some other possible causes.
Constipation
One of the most common causes of mucus in stool is constipation, says Dr. Terry. That’s because decreased bowel movements tend to create stools that are dry, hard, and difficult to pass.
Irritable Bowel Syndrome
Another common cause of mucus in stool is irritable bowel syndrome (IBS). It involves disruption in how the nerves within the digestive system work.
- Abdominal pain and cramping related to passing bowel movements
- Bloating
- Changes in how stool appears
- More or less frequent bowel movements
Inflammatory Bowel Disease
As the name implies, the two main types of inflammatory bowel disease (IBD), Crohn’s disease and ulcerative colitis, are both characterized by inflammation.
As mentioned, increased inflammation may lead to excess mucus production that ends up in the stool.
- Diarrhea
- Stomach pain
- Fatigue
- Nausea
- Unexplained weight loss
Gastrointestinal Infections
Whether your infection is caused by bacteria, viruses, or parasites, it can raise the level of inflammation within the digestive tract and affect the mucosa in your intestines.
Colorectal Cancer
When to See a Doctor
Occasional, very small amounts of mucus that come without any other symptoms are likely not enough to warrant a doctor’s appointment.
However, Dr. George suggests getting checked if mucus in stool is accompanied by other symptoms, such as:
- Fever
- Chills with bowel movements
- Blood in your stool
- Stool that’s black or tarry
- Bloating
- Fatigue
- Unexpected weight loss
- Abdominal pain
- Presence of mucus for over four weeks, particularly if the amount is increasing over time
“Additionally, if there is a family history of gastrointestinal disease or cancer, prompt evaluation is important,” says Terry. “A healthcare provider may recommend diagnostic testing, such as stool studies, endoscopy, or imaging, to determine the cause.”
The Takeaway
- Gluten intolerance can potentially lead to irritation of the intestinal lining. This may then prompt excess production of mucus.
- If you see mucus in your stool, it could be normal, especially if it’s only occasional. However, it could indicate gluten intolerance or another health condition, such as constipation, infection, IBS, or IBD.
- When mucus is accompanied by other symptoms like fever or abdominal pain, consider getting checked by your doctor.
Resources We Trust
Mayo Clinic: Irritable Bowel Syndrome
Cleveland Clinic: Gluten Intolerance
Penn State College of Medicine: The 14 Most Common Signs of Gluten Intolerance
Celiac Disease Foundation: Non-Celiac Gluten Sensitivity Shows Distinct Immune Response
Centers for Disease Control and Prevention: Inflammatory Bowel Disease
- Gluten Intolerance. Cleveland Clinic. June 30, 2021.
- The 14 Most Common Signs of Gluten Intolerance. Penn State College of Medicine. April 21, 2021.
- Mucosa. Cleveland Clinic. July 24, 2022.
- Waffle V. Non-Celiac Gluten Sensitivity Shows Distinct Immune Response. Celiac Disease Foundation.
- Mucus in Stool (Poop). Cleveland Clinic. March 3, 2025.
- Irritable bowel syndrome. Mayo Clinic. October 11, 2024.
- Inflammatory Bowel Disease (IBD) Basics. Centers for Disease Control and Prevention. June 21, 2024.

Yuying Luo, MD
Medical Reviewer
Yuying Luo, MD, is an assistant professor of medicine at Mount Sinai West and Morningside in New York City. She aims to deliver evidence-based, patient-centered, and holistic care for her patients.
Her clinical and research focus includes patients with disorders of gut-brain interaction such as irritable bowel syndrome and functional dyspepsia; patients with lower gastrointestinal motility (constipation) disorders and defecatory and anorectal disorders (such as dyssynergic defecation); and women’s gastrointestinal health.
She graduated from Harvard with a bachelor's degree in molecular and cellular biology and received her MD from the NYU Grossman School of Medicine. She completed her residency in internal medicine at the Icahn School of Medicine at Mount Sinai, where she was also chief resident. She completed her gastroenterology fellowship at Mount Sinai Hospital and was also chief fellow.
