Mucus in Stool: Is It a Symptom of Gluten Intolerance?

Can Gluten Intolerance Cause Mucus in Stool?

Can Gluten Intolerance Cause Mucus in Stool?
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You may not have celiac disease — an autoimmune disorder triggered by consuming the gluten protein in wheat, barley, and rye — but it’s possible you have gluten intolerance.

Gluten intolerance can bring on a range of symptoms, from bloating and nausea to fatigue and joint pain.

Changes in your stool can happen, too, with stools potentially becoming watery, pale, and foul-smelling.

Although it’s not a hallmark symptom of gluten intolerance, another part of that shift could be the presence of mucus, a clear and jelly-like substance, in your stool.

That’s because gluten intolerance could cause changes in your bowel habits, which may include increased mucus production in stool, says Nayana George, MD, a gastroenterologist at Orlando Health Digestive Health Institute in St. Petersburg, Florida.

A small amount of mucus in stool occasionally, such as the day after you eat gluten but not in your stool usually, is likely not a cause for concern. But pay attention to whether you’re having other symptoms, such as fever or chills, that may indicate a more serious issue, she says.

Here’s a look at why mucus may occur with gluten intolerance, other reasons you may see mucus, and when to consider checking in with your healthcare provider.

Mucus in Stool: Is It a Sign of Gluten Intolerance?

The mucous membrane, also called the mucosa, in your digestive system is a lining that protects your intestines from harmful substances while still letting nutrients and water absorb into the bloodstream.

To do this, the mucosa secretes a substance called mucus that lubricates the intestinal walls. It also contains immune cells that help maintain a healthy balance of gut bacteria.

When there’s disruption in the mucosa from inflammation, damage, or infection, that can cause an increase in mucus production to fight what the body sees as a threat.

When that happens, more of the mucus is shed through bowel movements, says Richard Terry, DO, family medicine physician and associate dean of academic affairs at Lake Erie College of Osteopathic Medicine in Elmira, Pennsylvania.

“Mucus in the stool can occur in individuals with gluten intolerance, though it is not one of the classic hallmark symptoms of that condition,” he says. It’s important to note, though, that this usually happens along with other bowel habit changes.

Gluten doesn’t do this for everyone. It only affects those with celiac disease, an intolerance, or a sensitivity to the protein, because those people have an immune system response when they consume foods with gluten.

Other Causes of Mucus in Stool

Gluten intolerance isn’t the only potential cause of mucus in stool. Here are some other possible causes.

Constipation

One of the most common causes of mucus in stool is constipation, says Dr. Terry. That’s because decreased bowel movements tend to create stools that are dry, hard, and difficult to pass.

When this happens, it can affect the mucosa because the increased effort to get hard stools out of your system can irritate the lining of the colon.

Irritable Bowel Syndrome

Another common cause of mucus in stool is irritable bowel syndrome (IBS). It involves disruption in how the nerves within the digestive system work.

Other symptoms of IBS include:

  • Abdominal pain and cramping related to passing bowel movements
  • Bloating
  • Changes in how stool appears
  • More or less frequent bowel movements

Inflammatory Bowel Disease

As the name implies, the two main types of inflammatory bowel disease (IBD), Crohn’s disease and ulcerative colitis, are both characterized by inflammation.

As mentioned, increased inflammation may lead to excess mucus production that ends up in the stool.

Symptoms of IBD can include:

  • Diarrhea
  • Stomach pain
  • Fatigue
  • Nausea
  • Unexplained weight loss

Gastrointestinal Infections

Whether your infection is caused by bacteria, viruses, or parasites, it can raise the level of inflammation within the digestive tract and affect the mucosa in your intestines.

You can also develop an infection in the small pockets (diverticula) in your colon. This is called diverticulitis.

Colorectal Cancer

In addition to creating excessive mucus in the intestines, colorectal cancer may cause bloody or dark black mucus in the stool. However, this is not common.

When to See a Doctor

Occasional, very small amounts of mucus that come without any other symptoms are likely not enough to warrant a doctor’s appointment.

However, Dr. George suggests getting checked if mucus in stool is accompanied by other symptoms, such as:

  • Fever
  • Chills with bowel movements
  • Blood in your stool
  • Stool that’s black or tarry
  • Bloating
  • Fatigue
  • Unexpected weight loss
  • Abdominal pain
  • Presence of mucus for over four weeks, particularly if the amount is increasing over time

“Additionally, if there is a family history of gastrointestinal disease or cancer, prompt evaluation is important,” says Terry. “A healthcare provider may recommend diagnostic testing, such as stool studies, endoscopy, or imaging, to determine the cause.”

The Takeaway

  • Gluten intolerance can potentially lead to irritation of the intestinal lining. This may then prompt excess production of mucus.
  • If you see mucus in your stool, it could be normal, especially if it’s only occasional. However, it could indicate gluten intolerance or another health condition, such as constipation, infection, IBS, or IBD.
  • When mucus is accompanied by other symptoms like fever or abdominal pain, consider getting checked by your doctor.

Resources We Trust

Mayo Clinic: Irritable Bowel Syndrome

Cleveland Clinic: Gluten Intolerance

Penn State College of Medicine: The 14 Most Common Signs of Gluten Intolerance

Celiac Disease Foundation: Non-Celiac Gluten Sensitivity Shows Distinct Immune Response

Centers for Disease Control and Prevention: Inflammatory Bowel Disease

EDITORIAL SOURCES
Everyday Health follows strict sourcing guidelines to ensure the accuracy of its content, outlined in our editorial policy. We use only trustworthy sources, including peer-reviewed studies, board-certified medical experts, patients with lived experience, and information from top institutions.
Resources
  1. Gluten Intolerance. Cleveland Clinic. June 30, 2021.
  2. The 14 Most Common Signs of Gluten Intolerance. Penn State College of Medicine. April 21, 2021.
  3. Mucosa. Cleveland Clinic. July 24, 2022.
  4. Waffle V. Non-Celiac Gluten Sensitivity Shows Distinct Immune Response. Celiac Disease Foundation.
  5. Mucus in Stool (Poop). Cleveland Clinic. March 3, 2025.
  6. Irritable bowel syndrome. Mayo Clinic. October 11, 2024.
  7. Inflammatory Bowel Disease (IBD) Basics. Centers for Disease Control and Prevention. June 21, 2024.

Yuying Luo, MD

Medical Reviewer

Yuying Luo, MD, is an assistant professor of medicine at Mount Sinai West and Morningside in New York City. She aims to deliver evidence-based, patient-centered, and holistic care for her patients.

Her clinical and research focus includes patients with disorders of gut-brain interaction such as irritable bowel syndrome and functional dyspepsia; patients with lower gastrointestinal motility (constipation) disorders and defecatory and anorectal disorders (such as dyssynergic defecation); and women’s gastrointestinal health.

She graduated from Harvard with a bachelor's degree in molecular and cellular biology and received her MD from the NYU Grossman School of Medicine. She completed her residency in internal medicine at the Icahn School of Medicine at Mount Sinai, where she was also chief resident. She completed her gastroenterology fellowship at Mount Sinai Hospital and was also chief fellow.

elizabeth-millard-bio

Elizabeth Millard

Author
Elizabeth Millard is a freelance writer based in northern Minnesota. She focuses on health, wellness, and fitness, and has written for Runner's World, Bicycling, Self, Women's Health, Men's Health, Prevention, Experience Life, and more. She is an American Council on Exercise–certified personal trainer and a Yoga Alliance-registered yoga teacher. She graduated from Harvard University with a bachelor's degree in English.