Typical signs of enterovirus can resemble a cold or the flu, but in a few cases the disease can be much more severe.
Enterovirus infections often have no symptoms, especially in adults.
In people who do have symptoms, they are usually mild, resembling the common cold. Some people experience
Symptoms of an enterovirus infection may include:
- Runny nose, sneezing, cough
- Sore throat
- Body and muscle aches
- Vomiting
- Fever
- Conjunctivitis (also known as pink eye or Madras eye)
- Non-itchy rash on the skin
- Sores on the mucous membranes, such as blisters inside the mouth
While most cases of enterovirus get better with rest and normal at-home care, in some people the illness can become very serious and require immediate medical attention.
You should especially watch out for severe illness in infants and people with weak immune systems.
Precautions should be taken for children with asthma or other lung problems, too, because they are more likely than others to develop serious breathing problems.
More severe symptoms may include:
- Difficulty breathing
- Chest pain
- Wheezing
- Blue lips
Serious but less common complications can include the central nervous system and heart.
It's possible for the virus to infect the brain (causing encephalitis) or inflame the membranes that envelop the spinal cord and brain (causing meningitis), which may have a broad range of neurological symptoms.
The virus can also inflame the sac around the heart (causing pericarditis), or even infect the heart muscle (causing myocarditis).
Symptoms may include:
- Fatigue
- Rapid heartbeat
- Chest pain
- Shortness of breath
- Swelling in the feet, ankles, or legs
Symptoms in Children
Symptoms of enterovirus infection tend to be more severe in children than in adults, but most children can still be treated with supportive care at home.
However, parents should seek immediate medical treatment for children who develop any of the following respiratory symptoms:
- Difficulty breathing
- Chest pain
- Wheezing
- Blue lips
Enterovirus D68 (EV-D68), which caused a nationwide outbreak of severe respiratory illness in 2014, was notable for causing these symptoms in some children, particularly those with asthma or other lung conditions.
It's also important to seek medical help for anyone who develops neurological symptoms, such as:
- Facial drooping
- Muscle weakness
- Paralysis
- Severe headache
- Seizures
In the 2014 outbreak, a small number of children who tested positive for EV-D68 developed these symptoms, although it was not absolutely certain they were caused by the virus.
Enterovirus Diagnosis
When doctors don't know the diagnosis of a patient who has severe enterovirus-like symptoms, they might do a test to identify the disease and find out how to treat it.
The test may entail taking a nasal or throat swab, collecting a stool sample, or doing a spinal tap.
There are antiviral medications that can be used to help treat severe cases of many types of enterovirus infections.
However, they were not effective against the EV-D68 enterovirus that caused the 2014 outbreak.
Instead, diagnostic tests of nasal and throat swabs were used mainly to help public health officials track the spread of the virus.

Robert Jasmer, MD
Medical Reviewer
Robert Jasmer, MD, is board certified in internal medicine, pulmonary disease, and critical care medicine. He is in private practice in Burlingame, California, where he specializing in interstitial lung disease, pulmonary infections, and obstructive lung disease. His favorite part of practice is the long-term personal relationships he develops with his patients.
Jasmer previously served as the associate program director of the Pulmonary and Critical Care Medicine Training Program at UCSF, and has also directed the UCSF Pulmonary and Critical Care Continuing Medical Education program. He was also the codirector of the medical intensive care unit at San Francisco General Hospital for nine years. He has published more than 30 peer-reviewed research studies and written 11 books or chapters on various topics in pulmonary diseases and critical care medicine. In addition to reviewing for Everyday Health, Jasmer has also written for publications like MedPageToday.
Jasmer is married and has a daughter and twin sons. In his personal time, he enjoys spending time with his family, trying out new restaurants, playing tennis, and keeping up with his children's busy schedules.

Ingrid Strauch
Author
Ingrid Strauch joined the Everyday Health editorial team in May 2015 and oversees the coverage of multiple sclerosis, migraine, macular degeneration, diabetic retinopathy, other neurological and ophthalmological diseases, and inflammatory arthritis. She is inspired by Everyday Health’s commitment to telling not just the facts about medical conditions, but also the personal stories of people living with them. She was previously the editor of Diabetes Self-Management and Arthritis Self-Management magazines.
Strauch has a bachelor’s degree in English composition and French from Beloit College in Wisconsin. In her free time, she is a literal trailblazer for Harriman State Park and leads small group hikes in the New York area.