Fluconazole is an antifungal medicine. It’s used to treat many types of fungal infections that affect different parts of the body, including the following areas:
- Mouth
- Throat
- Genitals
- Esophagus
- Abdomen
- Lungs
- Blood
- Other organs
This medicine may also be used to prevent a fungal infection in people who have a weak immune system.
Additionally, fluconazole is given to treat a certain type of meningitis (an infection of the membranes covering the brain and spine).
The medicine works by slowing the growth of fungi that cause an infection.
The U.S. Food and Drug Administration (FDA) approved fluconazole in 1990. It’s sold under the brand name Diflucan.
uses
What is Fluconazole (Diflucan) used for?
- Blastomycosis
- Candida Urinary Tract Infection
- Candidemia
- Coccidioidomycosis
- Coccidioidomycosis -- Meningitis
- Cryptococcal Meningitis -- Immunocompetent Host
- Cryptococcal Meningitis -- Immunosuppressed Host
- Cryptococcosis
- Esophageal Candidiasis
- Fungal Peritonitis
- Fungal Pneumonia
- Fungal Infection Prophylaxis
- Histoplasmosis
- Onychomycosis -- Fingernail
- Onychomycosis -- Toenail
- Oral Thrush
- Sporotrichosis
- Vaginal Candidiasis
- Fungal Infection -- Disseminated
- Systemic Candidiasis
warnings
What is the most important information I should know about Fluconazole (Diflucan)?
You should not use fluconazole if you are allergic to it.
May harm an unborn baby. Use effective birth control while using fluconazole and for at least 1 week after your last dose. Tell your doctor if you become pregnant.
Ask a doctor if it is safe to breastfeed while using this medicine.
Some drugs should not be used with fluconazole. Your treatment plan may change if you also use:
Tell your doctor if you have ever had:
The form of fluconazole contains sucrose. Talk to your doctor before taking this form of fluconazole if you have a problem digesting sugars or milk. liquid
- lemborexant, abrocitinib, theophylline, fentanyl, alfentanil, methadone, pimozide, tofacitinib, tolvaptan, or a vitamin A supplement;
- an antibiotic, antifungal, or antiviral medicine;
- a blood thinner;
- cancer medicine;
- cholesterol medication;
- oral diabetes medicine;
- heart or blood pressure medication;
- medicine for malaria or tuberculosis;
- medicine to prevent organ transplant rejection;
- medicine to treat depression or mental illness;
- an NSAID (nonsteroidal anti-inflammatory drug);
- seizure medicine; or
- steroid medicine.
- liver or kidney disease;
- low levels of potassium in your blood;
- heart problems; or
- if you are allergic to other antifungal medicine (such as ketoconazole, itraconazole, miconazole, posaconazole, voriconazole, and others).
User Reviews & Rating
Overall rating for Fluconazole (Diflucan)
Side Effects
What are the side effects of Fluconazole (Diflucan)?
Get emergency medical help if you have (hives, difficult breathing, swelling in your face or throat) (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling). signs of an allergic reactionor a severe skin reaction
Call your doctor at once if you have:
- fast or pounding heartbeats, fluttering in your chest, shortness of breath, and sudden dizziness (like you might pass out);
- seizure (convulsions);
- skin rash or skin lesions;
- decreased adrenal gland hormones--nausea, vomiting, stomach pain, loss of appetite, feeling tired or light-headed, muscle or joint pain, skin discoloration, craving salty foods; or
- liver problems--loss of appetite, stomach pain (upper right side), tiredness, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
- nausea, stomach pain, diarrhea, upset stomach;
- headache;
- dizziness; or
- changes in your sense of taste.
Common side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Pregnancy & Breastfeeding
Can I take Fluconazole (Diflucan) if I’m pregnant or breastfeeding?
May harm an unborn baby. Use effective birth control while using fluconazole and for at least 1 week after your last dose. Tell your doctor if you become pregnant.
Ask a doctor if it is safe to breastfeed while using this medicine.
Interactions
What drugs and food should I avoid while taking Fluconazole (Diflucan)?
Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.
Dosage Guidelines & Tips
How to take Fluconazole (Diflucan)?
Use Fluconazole (Diflucan) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Your dose will depend on the infection you are treating. Vaginal infections are often treated with only one pill. For other infections, your first dose may be a double dose. Carefully follow your doctor's instructions.
Fluconazole is taken by mouth. Fluconazole is given as an infusion into a vein. oral injection
You may take fluconazole with or without food. oral
Fluconazole is given as an infusion into a vein. A healthcare provider will give your first dose and may teach you how to properly use the medication by yourself. Prepare an injection only when you are ready to give it. Call your pharmacist for new medicine. injectionDo not use if the medicine looks cloudy, has changed colors, or has particles in it.
Use fluconazole for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication. Fluconazole will not treat a viral infection such as the flu or a common cold.
Shake the (liquid) before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon). oral suspension
Call your doctor if your symptoms do not improve, or if they get worse.
Store at room temperature away from moisture and heat. Do not freeze.
You may store the between 86 F (30 C) and 41 F (5 C), but do not allow it to freeze. Throw away any leftover liquid that is more than 2 weeks old. oral suspension
Use the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. use two doses at one time. Do not
Overdose Signs
What happens if I overdose on Fluconazole (Diflucan)?
What to Expect
For minor infections, your symptoms should improve within a week of taking fluconazole. If you have a more serious fungal infection, it may take one to two weeks.
Keep taking fluconazole for as long as your doctor tells you to, even if you start feeling better. This will help prevent the infection from returning.
Additional Dosage Information
Your dosage will depend on the type of infection you have, how serious your infection is, the formulation you take, your overall health, and other factors.
Secondary Uses
Fluconazole is used to treat many types of fungal infections, some of which aren’t listed in this medical guide.
Images
DIFLUCAN 50, ROERIG
Color: pink
Shape: trapezoid
Imprint: DIFLUCAN 50, ROERIG
DIFLUCAN 100, ROERIG
Color: pink
Shape: trapezoid
Imprint: DIFLUCAN 100, ROERIG
ROERIG, DIFLUCAN 200
Color: pink
Shape: trapezoid
Imprint: ROERIG, DIFLUCAN 200