Ulcerative Colitis Constipation: Why It Happens and How to Get Relief

When you have ulcerative colitis (UC), bowel issues can develop suddenly or turn into a chronic issue, and one of those difficulties is constipation.
What Causes Ulcerative Colitis Constipation?
With UC, inflammation is always a concern with any symptoms, and constipation isn't an exception, says Jakob Saidman, MD , a gastroenterology fellow at Northwell Lenox Hill Hospital in New York City.
When this system is disrupted — a situation that can happen more easily with UC — it's like a traffic jam where the signals are mixed up.
- Irritable bowel syndrome, or IBS (Yes, you can have UC and IBS at the same time.)
- Medication that slows the gut
- A diet low in fiber or with foods that irritate the gut lining, which might happen with food allergies or intolerances
- Low fluid intake even if it's not yet dehydration
Even stress can play a role here, since it can affect the enteric nervous system and lead to digestive changes, Saidman says.
How to Manage Ulcerative Colitis Constipation
Although constipation can be uncomfortable, the good news is that there are some ways to manage it. Here's what gastroenterologists recommend as a starting point.
1. Do a Medication Review
Because many types of medication — including some prescribed for UC — can cause constipation, it's helpful to have a conversation with your gastroenterologist or a pharmacist about what could be a possible culprit, says Saidman.
- Antidepressants
- Antihistamines
- Iron supplements
- Calcium channel blockers
- Diuretics
- GLP-1 drugs such as semaglutide (Ozempic) or tirzepatide (Zepbound)
- Pain relief meds like opioids and narcotics
Sometimes, one of these meds won't cause a problem on its own, but they may become an issue when taken in combination. That's why doing a medication review is useful, says Saidman.
2. Focus on Fiber
The role of dietary fiber in digestive health isn't just hype. While eating too much fiber can lead to constipation in rare cases, that's much less of an issue than getting too little, says Saidman.
3. Get More Exercise
Another way to reduce inflammation, improve blood flow in the digestive system, support that enteric nervous system, and reduce stress is to move more often, says Saidman.
"Any type of exercise stimulates the intestinal muscles, and that can have a meaningful effect on moving stool and reducing constipation," he says.
4. Train Your Brain
While strategies that get your digestive motor running are helpful, it's crucial to include your brain in the mix, says Ashkan Farhadi, MD, a gastroenterologist at MemorialCare Orange Coast Medical Center in Fountain Valley, California. The gut-mind connection is powerful, and it can be harnessed with a bit of training.
"You can condition your bowel by setting it up so you expect to go at the same time every day," he says. "The brain loves consistency and predictability, so if you tell the mind that this is the hour for evacuating the bowels, it will do that, and it learns quickly."
For example, let's say you want to have a bowel movement at 7 a.m. every day. Dr. Farhadi suggests sitting on the toilet at that time for 15 minutes, without straining or even trying to poop. Do this every day, even though nothing might happen at first. The point is that every day, you're telling your brain that this is your bowel's "deliver the shipment" time.
"You'd be amazed that after seven or eight days, your body begins to comply," he says. "Your brain begins to anticipate that this is what you want, at that exact time, and it will deliver."
5. Don't Postpone Bowel Movements
Sometimes, constipation happens because you may have been training your brain in a non-helpful way without realizing it, says Farhadi. For example, it's possible that whenever you've had mild urgency about needing to poop, you put it off to a more convenient time. By then, the bowel's nudging sensation may be gone.
"Postponing your bowel movements until they're at a better time is a good way to develop constipation, whether you have ulcerative colitis or not," he adds. "That's because you've been conditioning both your brain and your bowel to regard urgency as unimportant. You stopped listening to your body's signals, and when that happens, the body may adapt by not sending those signals anymore."
6. Talk to Your Doctor
- You have blood in your stool.
- You're losing weight without trying.
- Bowel movements cause you severe pain.
The Takeaway
- With UC, constipation can occur because of inflammation, but there may be other factors, such as medication complications, food intolerances or allergies, and stress.
- Lifestyle changes such as more fiber and more physical activity every day can ease constipation.
- Develop routine bowel movement habits to train your brain as well as your body to poop more predictably.
Resources We Trust
- Cleveland Clinic: Ulcerative Colitis
- Mayo Clinic: Dietary Fiber: Essential for a Healthy Diet
- Crohn's & Colitis Canada: Symptom Management: Constipation
- American Gastroenterological Association Patient Center: Inflammatory Bowel Disease (IBD): Role of Fiber
- Crohn's & Colitis UK: Constipation
- Miller C et al. Constipation in ulcerative colitis: Pathophysiology and practical management. Frontline Gastroenterology. August 2020.
- Constipation. Mayo Clinic. April 2025.
- Fleming II MA et al. The Enteric Nervous System and Its Emerging Role as a Therapeutic Target. Gastroenterology Research and Practice. September 2020.
- Cleveland NK et al. Ulcerative Colitis Patients Have Reduced Rectal Compliance Compared With Non-Inflammatory Bowel Disease Controls. Gastroenterology. January 2022.
- Constipation. Crohn's & Colitis UK. December 2023.
- Canasa (Mesalamine). Crohn's & Colitis Foundation.
- Constipation. Cleveland Clinic. July 18, 2023.
- Diuretics. Cleveland Clinic. December 4, 2024.
- Rojas Rojales PC et al. Nutritional knowledge, fiber intake, body mass index, and sex associated with constipation symptoms in Peruvian adults. Scientific Reports. April 12, 2025.
- Dietary Fiber: Essential for a healthy diet. Mayo Clinic. December 2024.
- Jiahe Cui et al. Physical activity and constipation: A systematic review of cohort studies. Journal of Global Health. November 2024.

Yuying Luo, MD
Medical Reviewer
Yuying Luo, MD, is an assistant professor of medicine at Mount Sinai West and Morningside in New York City. She aims to deliver evidence-based, patient-centered, and holistic care for her patients.
Her clinical and research focus includes patients with disorders of gut-brain interaction such as irritable bowel syndrome and functional dyspepsia; patients with lower gastrointestinal motility (constipation) disorders and defecatory and anorectal disorders (such as dyssynergic defecation); and women’s gastrointestinal health.
She graduated from Harvard with a bachelor's degree in molecular and cellular biology and received her MD from the NYU Grossman School of Medicine. She completed her residency in internal medicine at the Icahn School of Medicine at Mount Sinai, where she was also chief resident. She completed her gastroenterology fellowship at Mount Sinai Hospital and was also chief fellow.
