7 Key Facts About Colds and Flu if You Have Ulcerative Colitis

The good news is, you have plenty of options for preventing and treating a nasty cold or flu when you have UC. Here are seven key facts to know.
1. You Can Prevent Colds and Flu With Frequent Handwashing
2. If You Have Cold or Flu Symptoms, Tell Your Gastroenterologist Immediately
- Fever
- Chills
- Sore throat
- Cough
- Stuffy or runny nose
- Body aches
- Headaches
- Feeling exhausted
3. Your Gastroenterologist May Tell You to Pause Your Medications
“In some cases, we may need to temporarily hold their immunosuppressive medications, particularly during active infection, hospitalization, or complications from bacterial superinfection,” says Rahman.
4. You May Have a Higher Risk of Cold and Flu Complications
5. You Need a Flu Shot Every Year — but Not the Nasal Spray
6. Cold and Flu May Not Cause UC Flares, but You Should Still Take Extra Care
Some people stop taking their UC medications while they are sick with a cold or flu, but it’s vital to check with your provider before doing this, says Gaidos. “[Stopping your medications] is usually unnecessary and can result in an exacerbation of [UC] symptoms.”
If you have a cold or flu, Dam recommends taking it easy and getting plenty of rest. “Stay hydrated with water, broth, or tea, and eat easy-to-digest foods so your gut isn’t stressed,” says Dam.
7. Both Antiviral Meds and Home Remedies Can Improve Cold and Flu Symptoms
“I recommend drinking plenty of liquids, getting rest, and then addressing other symptoms (cough, congestion, sore throat) with over-the-counter cold and flu therapies,” says Gaidos. She also suggests hot tea with honey to help relieve a sore throat.
Dam’s go-to home remedies for cold and flu with UC are to drink warm fluids for comfort, use a humidifier for easier breathing, and eat foods gentle on the stomach, like rice, bananas, applesauce, and toast. Avoid nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen unless your doctor says it’s okay, because they can irritate the gut, says Dam. “Let your body rest — healing takes energy,” he says.
The Takeaway
- When you have ulcerative colitis, you carry a higher risk of catching a cold or the flu and developing complications from them.
- You can help prevent cold and flu by washing your hands often, wearing a mask in crowds, avoiding people who you know are sick, and getting a flu vaccine every year.
- If you have a cold or the flu, you may be treated with antiviral medication, but you can also ease symptoms with home remedies like a humidifier, warm fluids, and plenty of rest.
Resources We Trust
- Mayo Clinic: Flu Symptoms: Should I See My Doctor?
- Cleveland Clinic: Home Remedies for the Common Cold
- UCLA Health: Crohn's and Ulcerative Colitis Increase Flu Threat. What You Should Know
- Crohn's & Colitis Foundation: Influenza Information
- Centers for Disease Control and Prevention: People at Increased Risk for Flu Complications
- Craviotto V et al. Viral Infections in Inflammatory Bowel Disease: Tips and Tricks for Correct Management. World Journal of Gastroenterology. 2021.
- Farraye FA et al. ACG Clinical Guideline Update: Preventive Care in Inflammatory Bowel Disease. American Journal of Gastroenterology. 2025.
- Kröner PT et al. The Burden of Vaccine-preventable Diseases in Patients With Inflammatory Bowel Disease. Journal of Clinical Gastroenterology. 2022.
- Common Cold - Symptoms and Causes. Mayo Clinic. May 24, 2023.
- Flu (Influenza). Cleveland Clinic. 2022.
- About Handwashing. Centers for Disease Control and Prevention. February 16, 2024.
- Merz B. How to Prevent Infections. Harvard Health Publishing.
- Hand Sanitizer Guidelines and Recommendations. Centers for Disease Control and Prevention. March 12, 2024.
- Healthy Habits to Prevent Flu. Centers for Disease Control and Prevention. August 20, 2024.
- Cold Versus Flu. Centers for Disease Control and Prevention. August 8, 2024.
- Dennis T. Crohn’s and Ulcerative Colitis Increase Flu Threat. What You Should Know. UCLA Health. July 5, 2017.
- Signs and Symptoms of Flu. Centers for Disease Control and Prevention. August 26, 2024.
- Key Facts About Seasonal Flu Vaccine. Centers for Disease Control and Prevention. September 17, 2024.
- Dehghani T et al. Association Between Inflammatory Bowel Disease and Viral Infections. Current Microbiology. 2023.

Yuying Luo, MD
Medical Reviewer
Yuying Luo, MD, is an assistant professor of medicine at Mount Sinai West and Morningside in New York City. She aims to deliver evidence-based, patient-centered, and holistic care for her patients.
Her clinical and research focus includes patients with disorders of gut-brain interaction such as irritable bowel syndrome and functional dyspepsia; patients with lower gastrointestinal motility (constipation) disorders and defecatory and anorectal disorders (such as dyssynergic defecation); and women’s gastrointestinal health.
She graduated from Harvard with a bachelor's degree in molecular and cellular biology and received her MD from the NYU Grossman School of Medicine. She completed her residency in internal medicine at the Icahn School of Medicine at Mount Sinai, where she was also chief resident. She completed her gastroenterology fellowship at Mount Sinai Hospital and was also chief fellow.

Abby McCoy, RN
Author
Abby McCoy is an experienced registered nurse who has worked with adults and pediatric patients encompassing trauma, orthopedics, home care, transplant, and case management. She is a married mother of four and loves the circus — that is her home! She has family all over the world, and loves to travel as much as possible.
McCoy has written for publications like Remedy Health Media, Sleepopolis, and Expectful. She is passionate about health education and loves using her experience and knowledge in her writing.