Leptin Diet Guide: Benefits, Risks, and Foods to Avoid

Leptin Diet: What You Need to Know

Leptin Diet: What You Need to Know
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This eating plan is considered a fad diet. Fad diets often promote quick weight loss that is unsustainable and may severely restrict what you eat. They may be harmful and generally do not have long-lasting health benefits. Talk to your healthcare provider before making any major changes to how you eat.

If you’ve found yourself interested in diets that work with your hormones to help regulate or suppress hunger, you might have come across the leptin diet.

This diet focuses on leptin, a hormone known for its role in regulating appetite, to (supposedly) control hunger signals. By emphasizing specific eating windows and limiting carbohydrates, for example, the diet aims to "optimize" leptin levels, thus reducing unnecessary eating during the day.

There is currently a lack of research supporting the effectiveness of the leptin diet.

How Does the Leptin Diet Claim to Work?

The leptin diet was developed by Mary Richards and Byron J. Richards, a board-certified clinical nutritionist. It focuses on several key elements to optimize leptin levels, including:

  • Eating foods high in protein, especially at breakfast
  • Reducing carbohydrate intake
  • Limiting yourself to three meals per day, with no snacking in between meals
  • Finishing the last meal of your day at least three hours before bed
  • Eliminating large meals
Research has shown that leptin levels can play a role in regulating food intake, as well as impact how energy is used. Since leptin is released from fat cells, a larger amount of body fat can produce higher levels of leptin, leading to leptin resistance, or a reduced sensitivity to the hormone and the hunger cues it provides.

The leptin diet hopes to optimize leptin levels in the body so you can better control how much food your body signals you to eat.

What Can You Eat on the Leptin Diet?

The leptin diet encourages you to eat fresh and organic foods to limit chemicals or additives. It also suggests that your daily diet should be made up of 40 percent fat, 30 percent carbohydrates, and 30 percent proteins. Fiber intake is recommended to be between 30 and 50 grams, and you’re advised to have 8 to 16 ounces of water in between meals.

Foods to Include

  • Lean proteins, like chicken
  • Foods rich in omega-3s like salmon and nuts
  • Fresh fruits and vegetables higher in fiber, including broccoli, brussels sprouts, berries, and greens
  • Whole grains

Foods to Avoid

  • Soda
  • Artificial sweeteners
  • Energy drinks
  • Processed foods
  • Foods high in saturated fats, like butter
  • Foods high in carbohydrates like white bread, pastas, and pastries

Potential Benefits of the Leptin Diet

There is no direct, peer-reviewed research supporting the leptin diet, but the claimed benefits are weight loss and healthier leptin levels overall, which may help brain and metabolic functions.

One study shows that specific diets might have the potential to “recover sensitivity” to the hormone, but many questions still remain. Clinical studies of the benefit of healthy leptin levels have been limited in size and scope and results have been mixed as to its total benefit.

Importantly, research shows that leptin levels are not directly controlled by short-term diet changes but by weight and food intake over a longer period of time, meaning that a fad diet is unlikely to impact leptin levels anyway.

Potential Risks of the Leptin Diet

Like many fad diets, safety and efficacy are important. When certain important nutrients aren’t part of your daily intake due to diet restrictions, other health concerns may arise.

Since the leptin diet is considered a low-carbohydrate diet, certain nutrients, like fiber, might not be as big of a priority as they should be. This can lead to gastrointestinal symptoms like constipation.

The leptin diet can also be extremely restrictive with regard to when you’re allowed to eat. This can make it difficult to follow the diet and harder to sustain. For example, if you work until close to bedtime, it can be difficult to follow a diet restricting eating before bed.

Is the Leptin Diet Right for You?

While the leptin diet does offer some healthy suggestions like limiting artificial sweeteners and incorporating fruits and vegetables as part of a healthy diet, it’s important to remember that a diet must be sustainable for it to be effective in the long run. The leptin diet may provide you with quick results, but it might not be the long-term diet you’re looking for.

Before starting any diet, it is important to talk with your healthcare provider about its safety and your own personal health needs.

The Takeaway

  • The leptin diet claims to optimize leptin levels within your body.
  • The diet uses low carbohydrates and eating windows in an effort to reduce leptin resistance in the body.
  • There is currently no research supporting the effectiveness of this diet.
EDITORIAL SOURCES
Everyday Health follows strict sourcing guidelines to ensure the accuracy of its content, outlined in our editorial policy. We use only trustworthy sources, including peer-reviewed studies, board-certified medical experts, patients with lived experience, and information from top institutions.
Resources
  1. Sandra Pereira. Leptin and Metabolism. Endocrine Society. November 5, 2020.
  2. Kenny Mendoza-Herrera. The Leptin System and Diet: A Mini Review of the Current Evidence. Frontiers in Endocrinology. November 23, 2021.
  3. Leptin. Cleveland Clinic. January 2025.
Roxana Ehsani, RDN

Roxana Ehsani, RD

Medical Reviewer

Roxana Ehsani, RD, is a Miami-based licensed dietitian-nutritionist, board-certified specialist in sports dietetics, and media spokesperson, consultant, and content creator for food and nutrition brands. She is an adjunct instructor for sports nutrition at Virginia Tech in Blacksburg.

Ehsani appears as a food and nutrition expert for television stations across the nation and in national publications, including Runner's World, Women's Health, Glamour, and more, and is a contributing writer for EatingWell. She has a strong background in sports nutrition and has worked with professional, Olympic, collegiate, and high school teams and individual athletes, whom she sees through her private practice. 

Mary West

Author

Mary West is a health and nutrition writer, whose work has appeared in an array of online publications. He credits include Olive Oil Times, Live in the Now and Colgate.