We Asked 9 RDs What Probiotic Supplements They Recommend for Men — Here’s What They Said
While more research into the best probiotic strains for men’s health is needed, studies are examining the benefits of probiotics for the general population. Probiotic-rich foods like yogurt and kimchi are widely available, but men who don’t eat these foods may be looking for probiotic supplements to fill the gap. To help you sort through the noise, we consulted with nine nutrition experts to highlight the best probiotics for men based on lifestyle, stage of life, and health goals.
Our Top Picks for the Best Probiotics for Men
- Best With Prebiotics: Seed DS-01 Daily Synbiotic
- Best for Bloating: Align Probiotic Bloating Relief + Food Digestion
- Best for IBS: SFI Health Ther-Biotic Pro IBS Relief
- Best for Immune Support: Douglas Laboratories Multi-Probiotic 40 Billion
- Best for Vegetarians: Future Kind Vegan Probiotic
- Most Budget-Friendly: Now Foods Probiotic-10
- Best for Fertility Support: Needed Sperm Support+
- Best for Men Over 50: Garden of Life Raw Probiotics
- Best for Prostate Health: Hyperbiotics Pro-Men Probiotic
- Best for Weight Loss: Jarrow Formulas Jarro-Dophilus EPS
- Best High-Potency: Renew Life Ultimate Flora Men's Care Probiotic
- Best for Mental Health and Mood: Zenbiome Dual
- Best With a Multivitamin: AG1
- Best Subscription: Ritual Synbiotic+
When to Consult Your Doctor

Best With Prebiotics
Seed DS-01 Daily Synbiotic
Pros
- Researched probiotics and prebiotics
- Gut-friendly form of prebiotics
- Tested for bacterial survivability
- Third-party tested
Cons
- Some users may experience gas
- May cause histamine intolerance
Key Specs
- AFUs: 53.6 billion AFU
- Probiotic strains: 24 lactobacillus and bifidobacterium strains
- Other ingredients: Polyphenols
- Form: Capsule
- Serving size: 2 capsules
- Third-party tested: Yes
If you are seeking a high-quality, third-party-tested probiotic and your diet lacks fiber, Seed DS-01 Daily Synbiotic may be a good choice. This supplement blends 53.6 active fluorescent units (AFUs) of clinically studied probiotic strains with prebiotics, beneficial fibers that are a primary fuel source for the probiotic bacteria.
This probiotic is third-party tested, and the company conducts extensive testing of its own for allergens, pesticides, heavy metals, and more to ensure the highest safety and quality standards.
All Seed products are sold by subscription; you can choose deliveries every month, every three months, or every six months.

Best for Bloating
Align Probiotic Bloating Relief + Food Digestion
Pros
- Clinically studied strain for bloating
- Digestive enzyme blend
- B12 to break down food
Cons
- May cause gas and bloating
Key Specs
- CFUs: 1 billion
- Probiotic strains: Bifidobacterium longum 35624
- Other ingredients: B12, digestive enzyme blend
- Form: Capsule
- Serving size: 1 capsule
- Third-party tested: Yes

Best for IBS
SFI Health Ther-Biotic Pro IBS Relief
Pros
- Researched strains for gut health and IBS
- Gentle prebiotic for sensitive stomachs
- Third-party tested
Cons
- May cause gas
Key Specs
- CFUs: 20 billion
- Probiotic strains: Lactobacillus plantarum, Lactobacillus acidophilus, Bifidobacterium lactis
- Other ingredients: Sunfiber, polysaccharide complex
- Form: Capsule
- Serving size: 1 capsule
- Third-party tested: Yes
“SFI Health Ther-Biotic Pro IBS Relief is one of my top picks for IBS because it pairs well-studied probiotic strains with a gentle, gut-friendly prebiotic called partially hydrolyzed guar gum,” says Alyssa Simpson, RDN, a digestive health dietitian in Phoenix, Arizona.
SFI Health (formerly Klaire Labs) uses third-party testing to ensure the safety and potency of its products, and it’s transparent about sharing studies conducted on its ingredients in its FAQs section.
Some customers report receiving either an empty pill box or a smaller amount than ordered, so it’s important to check the package upon delivery. The company has a 30-day money-back guarantee return policy for any reason, including this one.

Best for Immune Support
Douglas Laboratories Multi-Probiotic 40 Billion
Pros
- Multiple strains to support immunity
- Prebiotics
- CGMP-certified
Cons
- Prebiotic fiber may cause gas
Key Specs
- CFUs: 40 billion
- Probiotic strains: 16 lactobacillus and bifidobacterium strains
- Other ingredients: Prebiotic fiber
- Form: Capsule
- Serving size: 2 capsules
- Third-party tested: Yes
Douglas Laboratories has been in business for 65 years and conducts regular in-house testing, and its products are certified for current good manufacturing processes (CGMP).

Best for Vegetarians
Future Kind Vegan Probiotic
Pros
- Vegan
- Clinically studied strains for men’s health
- Third-party tested
- CGMP certified
Cons
- Gellan gum may slow digestion
- Poor customer service reported
Key Specs
- CFUs: 30 billion
- Probiotic strains: Bacillus subtilis, Bifidobacterium breve, Bifidobacterium coagulans, B. lactis, Bifidobacterium longum, Lactobacillus casei, L. plantarum, L. rhamnosus, Lactobacillus salivarius, Lactobacillus acidophilus
- Other ingredients: None
- Form: Capsule
- Serving size: 1 capsule
- Third-party tested: Yes
If you follow a vegan lifestyle, Future Kind Vegan Probiotic contains nine bifidobacterium and lactobacillus strains in a vegan formulation that supports a healthy metabolism, digestion, immunity, and more.
This supplement undergoes regular independent testing to ensure that quality and safety standards are maintained. A certificate of analysis is available for transparency and added trustworthiness.
Some customers had difficulty reaching the company when trying to return products and report that shipping was very slow.

Most Budget-Friendly
Now Foods Probiotic-10
Pros
- Most affordable on our list
- Third-party tested
- CGMP certified
Cons
- May cause digestive distress
- Top may not seal tightly
Key Specs
- CFUs: 25 billion
- Probiotic strains: Lactobacillus, bifidobacterium, Streptococcus thermophilus
- Other ingredients: None
- Form: Capsule
- Serving size: 1 capsule
- Third-party tested: Yes
Now Foods Probiotic-10 is our top pick for the most budget-friendly men’s probiotic, as it contains 10 research-backed strains for as little as $8 for a month’s supply. “This budget-friendly probiotic is under $25 a bottle, making it easy on the wallet,” says Lauren Manaker, RDN, owner of Nutrition Now Counseling in Charleston, South Carolina. “It’s made with a blend of 10 strains of bacteria, provided in impressive quantities, with each supplement delivering a potency of 25 billion CFUs through the best-by date.”
All Now Foods probiotics are CGMP certified, ensuring that quality control measures are followed. In addition, the products are certified by Underwriters Laboratories, a reputable organization that requires strict safety, quality, and security standards.
Another factor that sets Now Foods apart is its dedication to charity and reducing malnutrition. It’s one of two founding members of Vitamin Angels, a nonprofit organization that donates essential vitamins to malnourished children worldwide, making the products more accessible to those who need them most.
Some customers report that the top of the container doesn’t always seal tightly, which could reduce its shelf life. A few users complain of worsened bloat and gas after taking this supplement. It’s important to monitor for symptoms when taking any probiotic supplement.

Best for Fertility Support
Needed Sperm Support+
Pros
- Clinically studied strains for fertility
- Sperm health and vitality blend
- Added prebiotics
- Third-party tested
Cons
- Fewer CFU count than other products on our list
Key Specs
- CFUs: 14 billion
- Probiotic strains: L. acidophilus NCFM, B. lactis BI-07, B. lactis BI-04, Bacillus clausii, Bacillus subtilis DE111
- Other ingredients: Pomegranate fruit extract, shilajit extract, NAC, alpha-lipoic acid, ashwagandha root and leaf extract, tongkat ali extract, Tribulus terrestris fruit extract, lycopene, green tea leaf extract, blueberry fruit extract
- Form: Capsule
- Serving size: 2 capsules
- Third-party tested: Yes

Best for Men Over 50
Garden of Life Raw Probiotics
Pros
- Variety of probiotics and nutrients
- Clinically studied strains for digestive, colon, immune health
- Whole-food based
- Third-party tested
Cons
- May not be suitable for people with a lactose intolerance
- Packaging can arrive warm
Key Specs
- CFUs: 85 billion
- Probiotic strains: 32, including lactobacillus, bifidobacterium, Brettanomyces, and saccharomyces strains
- Other ingredients: Digestive enzymes, fruit and vegetable blend, yogurt concentrate, vitamins, minerals
- Form: Capsule
- Serving size: 3 capsules
- Third-party tested: Yes
For men over 50, Garden of Life Raw Probiotics is a smart choice. In addition to a variety of probiotic strains, it contains several vitamins and minerals that can support nutritional health for men over 50.
If you have a vitamin deficiency and aren’t getting enough of your nutrients through food, taking this probiotic and vitamin supplement may help boost your nutrient levels and support your gut health at the same time. However, it’s likely not necessary if your vitamin levels are sufficient or you’re already taking a multivitamin.

Best for Prostate Health
Hyperbiotics Pro-Men Probiotic
Pros
- Six targeted probiotics and curcumin for prostate health
- Contains prebiotics
- Time-release technology for optimal absorption
- Easy-to-swallow tablet
Cons
- Fewest CFUs than all the products on our list
Key Specs
- CFUs: 5 billion
- Probiotic strains: L. acidophilus, L. casei, Lactobacillus fermentum, L. plantarum 6595, Lactobacillus reuteri, B. longum
- Other ingredients: Curcumin, prebiotics
- Form: Tablet
- Serving size: 1 tablet
- Third-party tested: Yes
Every ingredient used in Hyperbiotics products is third-party tested, and the company guarantees that the Pro-Men Probiotic contains at least 1.5 billion viable CFUs at the date of expiration. This probiotic also utilizes a time-release delivery system, which may help the live probiotics survive in the digestive tract.

Best for Weight Loss
Jarrow Formulas Jarro-Dophilus EPS
Pros
- Clinically studied strains for weight loss
- Third-party tested
- Coating to protect from stomach acid
- Vegetarian
Cons
- No prebiotics
- Damages easily
- Trace amounts of dairy and soy
Key Specs
- CFUs: 10 billion
- Probiotic strains: 8 bifidobacterium, lactobacillus, and pediococcus strains
- Other ingredients: None
- Form: Capsule
- Serving size: 2 capsules
- Third-party tested: Yes
This supplement is third-party tested for safety and quality, and is made in a facility certified by the National Sanitation Foundation (NSF), one of the most reputable third-party testing sites. However, it does contain trace amounts of dairy and soy, so those with milk or soy allergies should avoid it.
Some users report that the blister packs are easily damaged. If this happens to you, contact the seller.

Best High Potency
Renew Life Ultimate Flora Men’s Care Probiotic
Pros
- Highest CFU count on our list
- 12 diverse strains for men’s health
- Third-party tested
Cons
- High dose may lead to gas, bloating
- Strong citrusy scent
Key Specs
- CFUs: 90 billion
- Probiotic strains: 12 bifidobacterium and lactobacillus strains, including L. rhamnosus GG
- Other ingredients: None
- Form: Capsule
- Serving size: 1 capsule
- Third-party tested: Yes
Renew Life Ultimate Flora Men’s Care Probiotic contains 90 billion CFUs, with 12 diverse strains for men seeking digestive, colon, immune, and respiratory health support. “Renew Life Men's Care Probiotic Capsules are a good choice for men due to the diverse blend of 12 probiotic strains, including the extensively studied L. rhamnosus GG, which promotes gut health, boosts the immune system, and maintains a healthy gut microbiome,” says Simpson.
These supplements are free of dairy, soy, and gluten, and are third-party verified for probiotic potency and quality. Keep in mind that starting at a high dose like this may lead to gas and bloating, which typically resolves in a few weeks. A few customers also note that the pills have a strong citrus or flowery smell that is a bit overpowering.

Best for Mental Health and Mood
Zenbiome Dual
Pros
- Clinically studied strains for mental health
- Dual-action for digestive and mental health support
- Third-party tested
- Product transparency on the website
Cons
- Practitioner account required to purchase from the manufacturer
- Proprietary blend
Key Specs
- CFUs: 10 billion
- Probiotic strains: Proprietary blend, bifidobacterium species
- Other ingredients: None
- Form: Capsule
- Serving size: 2 capsules
- Third-party tested: Yes
“When consumed in adequate amounts, these probiotics improve gut diversity and may produce a mental health benefit. It provides these benefits by targeting the gut-brain axis, the nerve connection between the brain and gut,” says Archer. While we know there’s a connection between the gut and brain, more robust research is needed to confirm the connection between probiotics and mental health. We particularly appreciate the company’s transparency in sharing specific research studies on ingredients on the product pages.
To purchase directly from the website, you need a practitioner code, which you can get from a doctor, dietitian, or other qualified healthcare professional. You don’t need to this if you purchase on third-party websites such as Pure Formulas. However, it’s always best to speak to a healthcare professional prior to starting probiotics or any other supplement, regardless of where you make your purchase.

Best With a Multivitamin
AG1
Pros
- All-in-one probiotic plus multivitamin
- Contains prebiotics
- Added adaptogens and antioxidants
- Third-party tested
Cons
- Lacking in some vitamins and minerals
- Priciest on our list
Key Specs
- CFUs: 32 billion
- Probiotic strains: L. acidophilus, Bifidobacterium bifidum
- Other ingredients: Vitamins, minerals, adaptogens, antioxidants, mushroom powder, enzymes
- Form: Powder
- Serving size: 1 scoop
- Third-party testing: Yes
If you’re looking for an all-in-one probiotic plus a multivitamin, you may want to consider Athletic Greens, also known as AG1. This product combines a greens powder, multivitamin, probiotic, and prebiotic into a single daily scoop of powder. Greens powders are a dietary supplement to help people reach their daily intake of vitamins and minerals. However, not all greens powders contain probiotics.
AG1 is committed to the testing and safety of its ingredients, as evidenced by the NSF Certified for Sport designation. This certification is provided by one of the most reputable third-party testing agencies for ingredient purity, ensuring that no heavy metals, harmful pesticides, or banned athletic substances are present.

Best Subscription
Ritual Synbiotic+
Pros
- Convenient subscription service
- Contains pre-, pro-, and postbiotics
- Transparency in ingredient sourcing
- Third-party tested
Cons
- Minty taste may not appeal to all
- May cause gas and bloating
Key Specs
- CFUs: 11 billion
- Probiotic strains: L. rhamnosus, Bifidobacterium animalis ssp. lactis (BB-12)
- Other ingredients: Prebiotics, postbiotics
- Form: Capsule
- Serving size: 1 capsule
- Third-party testing: Yes
Signing up for a subscription service is a convenient way to build a consistent health routine to get the most benefits out of your supplements. Ritual Synbiotic+ is a three-in-one synbiotic, with a combination of probiotics, prebiotics, and postbiotics to support gut health.
Ritual products are third-party tested, and the company has a scientific advisory board of medical doctors, registered dietitians, and scientists who conduct ongoing research to ensure the safety, quality, and effectiveness of its products. Ritual values transparency, too; you can find where the ingredients for its products come from on its Traceable Ingredients webpage.
Comparison Table
How We Chose the Best Probiotic Supplements
We consulted with nine qualified nutrition experts, all of whom are registered dietitians, to select the best probiotics for men’s health. These experts are well versed in supplements and do not have any financial conflicts of interest. I’m also a registered dietitian, with over 18 years of experience in health and wellness.
Here are the specific characteristics we used to find the best probiotics for our list:
- Research-studied strains for men’s health
- Number of CFUs
- Addition of prebiotics and other ingredients
- Third-party testing or certification
- Brand trustworthiness
- Positive customer reviews
Here are the nine nutrition experts we consulted for additional expertise and insights:
- Kathryn Durston, RDN
- Caitlin Beale, RDN
- Alyssa Simpson RDN
- Jessica DeGore, RD, CDCES
- Lauren Panoff, RD
- Lauren Manaker, RDN
- Christa Brown, RDN
- Ana Reisdorf, RD
- Amy Archer, RDN
What to Look for When Buying a Probiotic Supplement
When shopping for the best probiotics for men, here are some key features to look for to make the most out of them.
Third-party testing: Our experts all agree that customers should seek out a probiotic that has undergone third-party testing or has been independently tested to ensure its quality, potency, and safety. A few of the most reputable third-party testing agencies are United States Pharmacopeia (USP) and the NSF. Other certifications that attest to quality are CGMP or Clean Label.
Potential allergens: Check for additional ingredients like lactose, gluten, or soy if you have any sensitivities, as these can affect tolerability.
FAQ
Why Trust Everyday Health

Melissa Mitri, MS, RD
Author
Melissa Mitri is a registered dietitian-nutritionist, weight loss specialist, and expert health writer with over 18 years of experience in the health and wellness industry. She owns Melissa Mitri Nutrition, a virtual private practice helping women achieve sustainable weight loss.
Melissa is a freelance writer and editor for dietitians and wellness brands. She helps translate complicated scientific research into easy-to-understand terms for the public. Melissa has written for various publications and websites, such as HealthCanal, WellnessVerge, Nature Made, Garden of Life, the Avocado Board, and more.
Melissa believes everyone has the power to improve their health, one small habit at a time. Her approach to healthy eating focuses on what to eat more of for better health versus what to restrict or eliminate in the diet.
Melissa lives in Connecticut with her husband and two boys, where she enjoys training for half-marathons, reading, and traveling with her family.
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