Protein and Blood Sugar

When eaten in moderation, protein has an overwhelmingly positive effect on metabolic health, helping slow the digestion of sugars and other carbohydrates, as well as aiding with weight management and muscle health. But protein can contribute to a gradual increase in glucose levels in people who eat very large amounts of it, and low-carb dieters may notice a blood sugar rise after heavy meals.
If you use insulin to manage diabetes, you may want to take your protein consumption into consideration when determining your mealtime doses.
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Does Protein Impact Blood Sugar?
For most people, protein stabilizes blood sugar rather than raises it, both by replacing carbohydrates and by slowing down their digestion.
Since it takes several hours to digest protein, it can help you stay fuller longer and regulate your blood sugar levels after you eat a meal or snack with carbohydrates, explains Toby Smithson, RDN, the senior manager of nutrition and wellness at the American Diabetes Association. She says the combination of lean protein and complex carbohydrates, like whole grains, starchy vegetables, and legumes, may offset the blood sugar effects of the carbs.
Protein and Metabolic Health
- Keep your blood sugar levels more stable after you eat
- Help you stay fuller longer and manage your weight
- Aid in building and maintaining muscle mass
- Support wound-healing, which in turn reduces infection risk
“Research shows that replacing animal protein with plant protein can help with blood glucose management,” Smithson says.
How Much Protein Should You Eat?
That said, your individual needs may depend on factors like your age, activity level, gender, muscle mass, and any other medical conditions you may have. For example, you may need more protein if you’re very active or less if you have kidney disease.
It also makes sense for those with diabetes to eat protein at all or most of their daily meals and snacks.
“To feel satisfied between meals and minimize large spikes in blood sugar, spacing protein-rich foods throughout the day can be helpful,” says Brown.
Does Fat Raise Blood Sugar?
“Fats are useful for slowing down digestion, meaning that sugar [from carbohydrates] also gets absorbed at a slower rate and blood sugar levels do not rise as rapidly,” Brown says.
When you’re choosing a protein source, be mindful of its fat content. Limit proteins like red meat and full fat dairy, which are typically high in saturated fat. Instead, reach for protein options like beans, legumes, low-fat dairy, nuts or nut butters, lean poultry, seafood, or soy.
Insulin Management Strategies for Protein
Although most people don’t need to worry about the blood sugar rise that large amounts of protein can cause, people with type 1 or type 2 diabetes who use insulin before meals may want to account for this effect.
It’s rare for protein to have a major impact on your blood sugar. But if you suspect that’s the case for you, Smithson recommends monitoring your blood glucose levels for post-meal trends.
“Having this data will give a person information to share with their healthcare provider and help people make informed decisions about their insulin management,” Smithson says.
If your blood sugar is rising too much after meals, you and your healthcare provider can decide on an action plan to keep your levels under control. You might opt to:
- Use additional insulin. If meals with extra protein (or fat) cause blood sugar spikes, you might need to use more insulin than your carbohydrate ratio predicts. Research suggests starting with an additional 30 percent.
- Use multiple injections for one meal. Take some insulin before you start eating, or soon afterward, to counteract the fast blood sugar rise caused by carbohydrates. Also take more insulin one or more hours later to counteract the gradual rise caused by protein. “Some people will split their mealtime insulin dose into two parts to account for a delayed increase in blood sugar levels, and others will preemptively add 10 to 20 percent to the amount of insulin they are taking,” Brown says.
- Ask about an insulin pump. Insulin pumps allow users to program complex insulin doses that are administered gradually over a period of hours — ideal to match the slow protein glucose rise.
- Ask about automated insulin delivery (AID). The latest insulin pumps can interact with a continuous glucose monitor (CGM) to automatically adjust your insulin delivery rate, says Brown. These may be able to detect and counteract a gradual delayed glucose spike without any input from the user at all.
The Takeaway
- Protein is digested more slowly than carbohydrates, and this can help stabilize blood sugar levels, particularly when protein is paired with complex carbs found in whole grains, vegetables, and legumes.
- Very large amounts of protein or protein in an extremely low-carb diet may lead to blood sugar spikes in some people.
- Eating enough protein has other benefits for those with diabetes. It can help you stay fuller longer, manage your weight, and maintain and build muscle mass, all of which lower the risk for long-term complications from the disease.
- People with diabetes, particularly those who use insulin, should monitor blood glucose levels before and after meals to determine how protein impacts your blood sugar.
Resources We Trust
- Cleveland Clinic: How to Follow a Diabetes-Friendly Diet
- Mayo Clinic: Diabetes Management: How Lifestyle, Daily Routine Affect Blood Sugar
- Mass General Brigham: How to Control Blood Sugar With Diet
- American Diabetes Association: Protein Food for Diabetes
- Johns Hopkins Medicine: Facts About Diabetes
- Amino Acids. Cleveland Clinic. December 22, 2021.
- Nuttall FQ et al. Dietary Protein and the Blood Glucose Concentration. Diabetes. April 16, 2013.
- Let’s Talk About Protein for People With Diabetes. American Diabetes Association. February 24, 2025.
- Ketogenic Diet. StatPearls. June 16, 2023.
- Viguiliouk E et al. Effect of Replacing Animal Protein with Plant Protein on Glycemic Control in Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Nutrients. December 1, 2015.
- How Much Protein Do You Need Every Day? Harvard Health Publishing. June 22, 2023.
- When It Comes to Protein, How Much Is Too Much? Harvard Health Publishing. July 23, 2024.
- What Is the Diabetes Plate? American Diabetes Association. January 15, 2025.
- Controlling Blood Glucose Levels Through Diet. Utah State University. March 1, 2023.
- Bell KJ et al. Impact of Fat, Protein, and Glycemic Index on Postprandial Glucose Control in Type 1 Diabetes: Implications for Intensive Diabetes Management in the Continuous Glucose Monitoring Era. Diabetes Care. June 2015.
- What Is Fat? American Diabetes Association.
- Manage Blood Sugar. Centers for Disease Control and Prevention. May 15, 2024.
- Sulik B et al. Carb Counting for Bolus Insulin Dosing: Consider Fat and Protein Content of Diet as Well. Cleveland Clinic Journal of Medicine. 2021.
- Paterson MA et al. High-Protein Meals Require 30% Additional Insulin to Prevent Delayed Postprandial Hyperglycaemia . Diabetic Medicine. April 16, 2020.
- Furthner D et al. The Role of Protein and Fat Intake on Insulin Therapy in Glycaemic Control of Paediatric Type 1 Diabetes: A Systematic Review and Research Gaps. Nutrients. October 11, 2021.

Reyna Franco, RDN
Medical Reviewer
Reyna Franco, RDN, is a New York City–based dietitian-nutritionist, certified specialist in sports dietetics, and certified personal trainer. She is a diplomate of the American College of Lifestyle Medicine and has a master's degree in nutrition and exercise physiology from Columbia University.
In her private practice, she provides medical nutrition therapy for weight management, sports nutrition, diabetes, cardiac disease, renal disease, gastrointestinal disorders, cancer, food allergies, eating disorders, and childhood nutrition. To serve her diverse patients, she demonstrates cultural sensitivity and knowledge of customary food practices. She applies the tenets of lifestyle medicine to reduce the risk of chronic disease and improve health outcomes for her patients.
Franco is also a corporate wellness consultant who conducts wellness counseling and seminars for organizations of every size. She taught sports nutrition to medical students at the Albert Einstein College of Medicine, taught life cycle nutrition and nutrition counseling to undergraduate students at LaGuardia Community College, and precepts nutrition students and interns. She created the sports nutrition rotation for the New York Distance Dietetic Internship program.
She is the chair of the American College of Lifestyle Medicine's Registered Dietitian-Nutritionist Member Interest Group. She is also the treasurer and secretary of the New York State Academy of Nutrition and Dietetics, having previously served in many other leadership roles for the organization, including as past president, awards committee chair, and grant committee chair, among others. She is active in the local Greater New York Dietetic Association and Long Island Academy of Nutrition and Dietetics, too.
