Diabetes and Sexual Dysfunction

It’s not often discussed, but diabetes can lead to sexual dysfunction in both men and women. Erectile dysfunction, decreased sex drive, a decline in fertility, and vaginal dryness may all result from damage to the small blood vessels and nerves caused by chronic hyperglycemia. The body’s sexual response depends on nerve signals that communicate with the brain and adequate blood flow, both of which can be compromised by high blood sugar.
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Does Diabetes Affect Sex Drive?
Dr. Houman says high blood sugar can also cause hormonal imbalances in women, reducing levels of testosterone and estrogen, which also plays a role in sex drive. “Fatigue from uncontrolled diabetes may also reduce interest in sex,” he adds.
Diabetes and Erectile Dysfunction
Treatments for ED
For men with diabetes, there’s a significant ED remedy at hand: better blood sugar control. If your ED is ultimately caused by hyperglycemia, your complications can be lessened or reversed if you can keep your blood sugar in a healthy range.
- avanafil (Stendra)
- sildenafil (Viagra)
- tadalafil (Cialis)
- vardenafil
Other Male Sexual Dysfunction Issues
Beyond ED and low testosterone, there are other sexual complications in men with diabetes.
Retrograde Ejaculation
Like erectile dysfunction, retrograde ejaculation is caused by nerve damage from prolonged high blood sugar levels, says Houman. It can also be precipitated by prostate surgery and certain medications. If the condition is suspected, a urine sample is used to detect semen and diagnose retrograde ejaculation. There are both pharmaceutical and surgical treatments available.
Peyronie’s Disease
Sexual Dysfunction in Women With Diabetes
- Reduction or loss of sexual interest or desire
- Arousal difficulties or vaginal dryness
- Loss of the ability to reach orgasm
The causes of sexual dysfunction are essentially the same for women with diabetes as those for men, but sexual dysfunction in women may also be attributed to gynecologic infections, pregnancy-related issues, menopause, and other health problems, says Dr. Parish.
Treatment for Issues in Women With Diabetes
- Vaginal lubricants and moisturizers, which are available both over-the-counter and in prescription strength, can help with dryness
- Learned techniques such as certain positions or stimulation during sexual interactions
- Kegel exercises for stronger pelvic muscles to help with sexual response
- Counseling to help manage any underlying anxiety, depression, or sexual performance worries
Psychological and Emotional Aspects
Sexual issues related to diabetes can strain intimate relationships, so it’s important to communicate well with your partner.
“Open and honest discussions about sexual concerns can reduce stress and help find alternative ways to maintain intimacy,” Houman says.
He adds that mental health therapy or couples’ counseling can help facilitate these conversations and address anxiety, depression, or relationship stress that can make problems in the bedroom even worse.
It’s also helpful to remember that sexual dysfunction in diabetes is common and treatable. This may encourage you to seek solutions rather than withdraw from intimacy, Houman says.
The Takeaway
- Diabetes is a common cause of sexual dysfunction in both men and women due to poor blood flow, nerve damage, and hormonal imbalances.
- For men, diabetes increases the risk of erectile dysfunction, retrograde ejaculation, and low testosterone. Women may experience low libido, painful intercourse, and difficulties with arousal and orgasm.
- These conditions are treatable with blood sugar management, medical advice, prescription medications, and lifestyle adjustments that can restore sexual health and improve intimacy.
- Improving communication with your partner can also help you deal with sexual dysfunction and strengthen your relationship.
Resources We Trust
- Cleveland Clinic: Low Libido (Low Sex Drive)
- Mayo Clinic: Female Sexual Dysfunction
- Johns Hopkins Medicine: Erectile Dysfunction
- Centers for Disease Control and Prevention: Common Sexual Health Problems and Who Can Help
- American Diabetes Association: Sexual Health
- Sex and Diabetes. American Diabetes Association.
- Elabbady A et al. Studying the Effect of Type 2 Diabetes Mellitus on Prostate-Related Parameters: A Prospective Single Institutional Study. Prostate International. August 2016.
- Low Testosterone. American Diabetes Association.
- Defeudis G et al. Erectile Dysfunction and Diabetes: A Melting Pot of Circumstances and Treatments. Diabetes/Metabolism Research and Reviews. September 2021.
- Definition & Facts for Erectile Dysfunction. National Institute of Diabetes and Digestive and Kidney Diseases. October 2024.
- Chu NV et al. Diabetes and Erectile Dysfunction. Clinical Diabetes. January 2001.
- Rajfer J. Relationship Between Testosterone and Erectile Dysfunction. Reviews in Urology. 2000.
- Ye J et al. Diabetes Mellitus Promotes the Development of Atherosclerosis: The Role of NLRP3. Frontiers in Immunology. June 28, 2022.
- Blood Pressure Drugs and ED: What You Need to Know. Harvard Health Publishing.
- Antidepressants: Which Cause the Fewest Sexual Side Effects? Mayo Clinic. August 24, 2024.
- Erectile Dysfunction: Viagra and Other Oral Medications. Mayo Clinic. June 24, 2023.
- Erectile Dysfunction. Cleveland Clinic. August 28, 2023.
- Mao YS et al. Retrograde Ejaculation as an Initial Presenting Symptom of Type 2 Diabetes Mellitus: A Case Report and Literature Review. Journal of Men’s Health. February 2022.
- Retrograde Ejaculation. Cleveland Clinic. September 28, 2021.
- Habous M et al. Peyronie’s Disease is Common in Poorly Controlled Diabetics But is Not Associated With the Metabolic Syndrome. Urology Annals. July-September 2019.
- Gianazza S et al. Peyronie’s Disease Development and Management in Diabetic Men. Andrology. June 2022.
- Shindel AW et al. Sexual Dysfunction in Diabetes. Endotext. June 8, 2021.
- Massud N et al. Frequency of Sexual Dysfunction in Women With Diabetes Mellitus: A Cross=Sectional Multicenter Study. Journal of Diabetology. July-September 2021.
- Paudel S et al. Systematic Review of Literature Examining Bacterial Urinary Tract Infections in Diabetes. Journal of Diabetes Research. May 17, 2022.
- Female Sexual Dysfunction. Mayo Clinic. October 20, 2024.
- Maiorino MI et al. Diabetes and Sexual Dysfunction: Current Perspectives. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy. March 6, 2014.

Sandy Bassin, MD
Medical Reviewer
Sandy Bassin, MD, is an endocrinology fellow at Mount Sinai in New York City. She is passionate about incorporating lifestyle medicine and plant-based nutrition into endocrinology, particularly for diabetes and obesity management.
She trained at the Geisel School of Medicine at Dartmouth, where she taught culinary medicine classes to patients and medical trainees. She continued her training at the Robert Wood Johnson Medical School.
Dr. Bassin has published reviews of nutrition education in medical training and physical activity in type 2 diabetes in Nutrition Reviews, Endocrine Practice, and the American Journal of Lifestyle Medicine. She has been featured on the Physician to Physician Plant-Based Nutrition podcast and given many presentations on lifestyle interventions in endocrine disorders.
She stays active through yoga and gardening, and loves to cook and be outdoors.

Lauren Bedosky
Author
When she's not writing about health and fitness — her favorite topics being anything related to running and strength training — she's reading up on the latest and greatest news in the field and working on her own health goals.