Abdominal Pain: Is It Appendicitis or Something Else?

Abdominal Pain: Is It Appendicitis or Something Else?

Abdominal Pain: Is It Appendicitis or Something Else?
Thinkstock

Appendicitis develops when your appendix — a small pouch attached to your large intestine — becomes inflamed.

The most obvious sign of appendicitis is a sharp pain in your abdomen, but the symptom can have many other causes.

Here’s everything you need to know about appendicitis belly pain, how it differs from other conditions that cause a similar type of pain, and what to do if you think you have appendicitis.

How Exactly Does Appendicitis Belly Pain Feel?

Most often, the pain you feel when you have appendicitis begins as a dull ache around your belly button that shifts to your lower right abdomen, where your appendix is located.

Additional symptoms that may indicate appendicitis include:

  • Pain that comes on suddenly
  • Pain that becomes significantly worse over a few hours
  • Pain that starts before other co-occurring symptoms, such as fever, nausea, and vomiting
  • Loss of appetite
  • Pain that worsens when you move around, breathe deeply, cough, sneeze, or experience other jarring motions
Signs a healthcare professional might look for include:

  • Pain at “McBurney’s Point” — the area where your appendix is, in the lower right abdomen between your belly button and your hip bone
  • Pain when someone applies and then quickly releases pressure in your lower right abdomen, a symptom called “rebound tenderness”
  • Unconsciously guarding your lower right abdomen when someone tries to touch it
  • Pain when someone applies resistance to your right knee as you try to lift that leg up while lying on your back
  • Aching in your abdomen when you move your bent right knee to the left and right while lying on your back.

“Classic appendicitis pain, which is the migration from the mid-stomach to the McBurney’s point, is a unique feature of appendicitis pain,” says Austin Shuxiao, MD, a board-certified internal medicine doctor and the founder of the mobile IV therapy provider Peach IV in New York City.

“The nature of the pain also shifts, which is unique to appendicitis,” Dr. Shuxiao explains. “Early on, when the pain is mid-abdomen, it is dull. As it migrates to the right lower quadrant, it will become sharper and more intense, because the inflammation is progressing, and irritating more local structures.”

Despite these classic signs, sometimes appendicitis pain can look like other conditions.

Other Causes of Belly Pain vs. Appendicitis

A study that looked at appendectomies over 10 years suggested that more than 8 percent of those performed were conducted on patients who didn’t have appendicitis.

This is because several other health issues can cause pain that’s localized in your lower right abdominal area, making an accurate diagnosis of appendicitis difficult without using blood or imaging tests, such as a computed tomography (CT) scan or an ultrasound.

Ovulation Pain

For women, ovulation pain occurs on either the right or left side of the lower abdomen and can sometimes feel like appendicitis pain. The pain is different in that it doesn't start near the belly button, nor does it get worse with movement.

Constipation

Constipation can cause pain localized in the lower right abdomen, as well as rebound tenderness. But the constipation starts before the abdominal pain, unlike when you have appendicitis — though constipation can be a symptom of appendicitis.

Kidney Infection

A kidney infection can be another cause of lower right abdominal pain — if the right kidney is infected — but this also causes groin pain, back pain, and painful urination.

Kidney Stones

Pain from kidney stones can spread to the lower right abdomen, though it doesn’t start at the belly button; it usually starts below the ribs on one of your sides and back. It also usually comes in waves.

Ovarian Cysts

Ovarian cysts often come with no noticeable symptoms, but for some women, pain can develop. Pain caused by ovarian cysts can be either dull or sharp, intermittent or constant, mild or severe. Sometimes it can be so bad that it causes nausea and vomiting, which are symptoms similar to appendicitis.

Ovarian cysts are also often on one side, depending on which ovary is housing the cyst. If the cyst and thus pain are on the right side, it could be very difficult to determine if the pain is due to an ovarian cyst or appendicitis.

Ectopic Pregnancy

Ectopic pregnancy, in which a fertilized egg gets implanted outside the uterus, can result in right-sided abdominal pain.

Unlike appendicitis, ectopic pregnancy is often marked by cramp-like pain, and sometimes even shoulder and neck pain.

Vaginal bleeding is also a common symptom of an ectopic pregnancy.

Other Common Causes of Abdominal Pain

Aside from appendicitis, some of the most common causes of abdominal pain include:

Your primary care provider — or if symptoms are severe, an emergency room physician — can order lab work and other tests to help determine what is causing your symptoms.

Is Appendicitis Belly Pain an Emergency?

Appendicitis is a medical emergency. If you experience any concerning symptoms such as severe abdominal pain, fever, or nausea, go to the nearest emergency room immediately. A doctor can diagnose appendicitis, prescribe needed treatments, and reduce the chances of complications.

The first step in diagnosis is a physical exam. A doctor will look for those classic appendicitis signs and symptoms, such as migrating pain that settles over McBurney’s Point, rebound pain, and guarding.

If you show these telltale signs, you will likely get a prompt diagnosis of appendicitis.

If not, you may require additional testing. This may include blood work, or a CT (computed tomography) scan, ultrasound, or MRI (magnetic resonance imaging) to rule out other potential causes of abdominal pain.

Treatment for appendicitis usually includes pain medication and antibiotics to clear the infection.

Most people with appendicitis will need to have their infected appendix surgically removed to prevent serious complications like a ruptured appendix.

“In the case of appendicitis, early diagnosis can prevent complications like rupture, which can lead to peritonitis — a life-threatening infection requiring emergency treatment,” says Shuxiao. “Prompt attention can make all the difference.”

The Takeaway

  • Appendicitis pain starts at the belly button and moves down to the lower right side of the abdomen, where it usually becomes severe and is accompanied by nausea, vomiting, and fever.
  • Appendicitis pain can look like other conditions that also cause abdominal pain, such as ovarian cysts, ectopic pregnancy, and even constipation.
  • If you think you are experiencing appendicitis pain, go to the emergency room.
  • Treatment for appendicitis almost always involves surgery to remove the infected appendix.

Common Questions & Answers

What is the most common symptom of appendicitis?
The most common symptom of appendicitis is sharp pain in the abdomen.
Some other possible causes of abdominal pain include gallstones, ovarian cysts, irritable bowel syndrome, urinary tract infection, and Crohn's disease.
The type of pain, such as cramping that is severe but comes and goes in waves, or nonlocalized pain, can indicate the possible cause of abdominal pain.
Signs of appendicitis include pain that starts around the belly button and shifts to the lower right abdomen, sudden onset of pain, loss of interest in eating, and worsening of pain with movement or jarring motions.
Other conditions that can cause lower right abdominal pain include ovulation pain, constipation, kidney infection, kidney stones, and ovarian cysts.

Resources We Trust

Additional reporting by Shelby House, BSN, RN.
EDITORIAL SOURCES
Everyday Health follows strict sourcing guidelines to ensure the accuracy of its content, outlined in our editorial policy. We use only trustworthy sources, including peer-reviewed studies, board-certified medical experts, patients with lived experience, and information from top institutions.
Resources
  1. Appendicitis. Mayo Clinic. January 18, 2025.
  2. Appendicitis. Cleveland Clinic. May 9, 2023.
  3. Chaochankit W et al. Negative appendectomy rate in patients diagnosed with acute appendicitis. BMC Surgery. November 22, 2022.
  4. Ovulation Pain. Cleveland Clinic. February 9, 2023.
  5. Constipation. Johns Hopkins Medicine. June 16, 2025.
  6. Symptoms & Causes of Kidney Infection (Pyelonephritis). National Institute of Diabetes and Digestive and Kidney Diseases. October 2024.
  7. Symptoms & Causes of Kidney Stones. National Institute of Diabetes and Digestive and Kidney Diseases. May 2017.
  8. Mobeen S et al. Ovarian Cyst. StatPearls. June 5, 2023.
  9. Ectopic Pregnancy. MedlinePlus. March 31, 2024.
  10. Abdominal Pain. Cleveland Clinic. April 18, 2022.
  11. Symptoms and Causes of Appendicitis. National Institute of Diabetes and Digestive and Kidney Diseases. July 2021.
Allison Buttarazzi, MD

Allison Buttarazzi, MD

Medical Reviewer

Allison Buttarazzi, MD, is board-certified in internal medicine and lifestyle medicine, and is a certified health and well-being coach. In her primary care practice, Dr. Buttarazzi focuses on lifestyle medicine to help her patients improve their health and longevity, and her passion is helping patients prevent and reverse chronic diseases (like heart disease, high blood pressure, and diabetes) by improving their lifestyle habits.

She is a graduate of Tufts University School of Medicine and completed a residency at Maine Medical Center. Diagnosed with celiac disease during medical school, she realized the power of improving one's health through diet and lifestyle habits, which she later incorporated into her practice.

Joseph Bennington-Castro

Author

Joseph Bennington-Castro is a science writer based in Hawaii. He has written well over a thousand articles for the general public on a wide range topics, including health, astronomy, archaeology, renewable energy, biomaterials, conservation, history, animal behavior, artificial intelligence, and many others.

In addition to writing for Everyday Health, Bennington-Castro has also written for publications such as Scientific American, National Geographic online, USA Today, Materials Research Society, Wired UK, Men's Journal, Live Science, Space.com, NBC News Mach, NOAA Fisheries, io9.com, and Discover.