What Really Happens to Your Body When You Drink a Glass of Wine Every Night

A nightly glass of red wine is a common ritual, and one that is considered to come with some benefits. But regularly drinking alcohol can also come with downsides that are important to consider as well.
Read on to learn more about what happens to your body when you drink a glass of wine every night.
Defining ‘Moderate Drinking’
According to the U.S. Centers for Disease Control and Prevention (CDC), “moderate drinking” is defined as one drink per day for women and two for men. The U.S. Department of Agriculture (USDA) defines one serving of red table wine as 5 ounces (oz).
Drawbacks of Moderate Red Wine Consumption
Research shows that drinking alcohol comes with health risks, which vary in severity depending on the amount someone drinks regularly.
Mental Health
According to some research, moderate wine consumption (between two and seven drinks per week) may be associated with a lower risk of having depression.
But the same study found that heavy drinking (consuming seven or more drinks per week) is actually linked to a higher risk for depression.
Extra Calories
While one glass of red wine each night isn't likely to cause changes in weight, the caloric content of red wine is still something worth considering.
According to the USDA, one serving of red table wine contains about 125 calories. This means that a nightly glass of red wine could add 875 calories to a person's average weekly intake.
If weight loss or weight maintenance is your goal, try going with two to three glasses of wine per week. If you want to enjoy a glass nightly, try diluting 3 oz of wine with 2 oz of sparkling water.
Sleep
Alcohol is considered a sedative and if you're drinking your glass of wine right before bedtime, it's probably going to make you sleepy — but that's not necessarily good news.
"One of the drawbacks of having a glass of wine every night is that it could affect the quality of sleep," says KeyVion Miller, RDN.
At a low dose, such as one glass per night, you may actually fall asleep faster. But as the alcohol is metabolized and eliminated from your body, research shows you may not be able to stay asleep.
Teeth
The American Dental Association notes that red wine is a source of extrinsic stains on the enamel of teeth.
Alcohol Use Disorder
Not everyone who drinks alcohol will develop alcohol use disorder, and there is a difference between this condition and moderate drinking.
But researchers point out that drinking still carries the potential increased misuse — even among those who are apparently at low risk.
Benefits of Moderate Red Wine Consumption
While there are negative effects associated with alcohol, some research does show that moderate alcohol consumption may have some benefits, namely during meals.
Gut Health
Research has shown that moderate red wine consumption may contribute to increased gut diversity. It's worth noting that white wine showed a lesser (yet still positive) effect, but the same association wasn't found with beer or spirits.
Heart Health
Mayo Clinic says red wine has antioxidants called polyphenols that may protect the lining of the heart's blood vessels, prevent blood clots, and lower the “bad” LDL cholesterol. Other studies, however, have found no connection here, and more research is needed.

Justin Laube, MD
Medical Reviewer
Justin Laube, MD, is a board-certified integrative and internal medicine physician, a teacher, and a consultant with extensive expertise in integrative health, medical education, and trauma healing.
He graduated with a bachelor's in biology from the University of Wisconsin and a medical degree from the University of Minnesota Medical School. During medical school, he completed a graduate certificate in integrative therapies and healing practices through the Earl E. Bakken Center for Spirituality & Healing. He completed his three-year residency training in internal medicine at the University of California in Los Angeles on the primary care track and a two-year fellowship in integrative East-West primary care at the UCLA Health Center for East-West Medicine.
He is currently taking a multiyear personal and professional sabbatical to explore the relationship between childhood trauma, disease, and the processes of healing. He is developing a clinical practice for patients with complex trauma, as well as for others going through significant life transitions. He is working on a book distilling the insights from his sabbatical, teaching, and leading retreats on trauma, integrative health, mindfulness, and well-being for health professionals, students, and the community.
Previously, Dr. Laube was an assistant clinical professor at the UCLA Health Center for East-West Medicine and the David Geffen School of Medicine at UCLA, where he provided primary care and integrative East-West medical consultations. As part of the faculty, he completed a medical education fellowship and received a certificate in innovation in curriculum design and evaluation. He was the fellowship director at the Center for East-West Medicine and led courses for physician fellows, residents, and medical students.

Sarah Pflugradt, PhD, RDN, CSCS
Author
Sarah Pflugradt is a registered dietitian with a PhD in Health and Human Performance. Sarah has authored two books, Live to Eat Well and Better Daily Weight Loss Habits. Sarah's website, Sarah Pflugradt Nutrition, provides easy healthy food ideas, and Fueling Active Kids is a performance nutrition resource for coaches and parents of active kids.